Rescue of cAMP response element-binding protein signaling reversed spatial memory retention impairments induced by subanesthetic dose of propofol

CNS Neuroscience and Therapeutics

Volumn 19, Issue 7, 2013, Pages 484-493

  Zhang, Hao ^a   Zhang, Shao Bo ^a   Zhang, Qing Qing ^a   Liu, Meng ^a   He, Xing Ying ^a   Zou, Zui ^a   Sun, Hai Jing ^a   You, Zhen Dong ^a,b   Shi, Xue Yin ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Amnesia; CREB signaling; Propofol; Rolipram

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; PROPOFOL; ROLIPRAM;

ANESTHESIA COMPLICATION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HIPPOCAMPUS; LATENT PERIOD; LEARNING; LOW DRUG DOSE; MALE; MAZE TEST; MEMORY CONSOLIDATION; MEMORY DISORDER; MOTOR PERFORMANCE; NONHUMAN; PREMEDICATION; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; RAT; ROTAROD TEST; SEDATION; SIGNAL TRANSDUCTION; SPATIAL MEMORY; TASK PERFORMANCE;

ANESTHETICS, INTRAVENOUS; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CUES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; HYPNOTICS AND SEDATIVES; MALE; MAP KINASE SIGNALING SYSTEM; MAZE LEARNING; MEMORY; MEMORY DISORDERS; PHOSPHODIESTERASE INHIBITORS; PHOSPHORYLATION; POSTURAL BALANCE; PROPOFOL; PROTO-ONCOGENE PROTEINS C-AKT; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; ROLIPRAM; SIGNAL TRANSDUCTION; SPACE PERCEPTION;

EID: 84879010304     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12088     Document Type: Article

References (51)

1. Veselis RA. Memory: A guide for anaesthetists. Best Pract Res Clin Anaesthesiol 2007;21:297-312.
2. Ren Y, Zhang FJ, Xue QS, Zhao X, Yu BW. Bilateral inhibition of gamma-aminobutyric acid type A receptor function within the basolateral amygdala blocked propofol-induced amnesia and activity-regulated cytoskeletal protein expression inhibition in the hippocampus. Anesthesiology 2008;109:775-781.
3. Wang DS, Orser BA. Inhibition of learning and memory by general anesthetics. Can J Anaesth 2011;58:167-177.
4. Veselis RA, Pryor KO, Reinsel RA, Mehta M, Pan H, Johnson R Jr. Low-dose propofol-induced amnesia is not due to a failure of encoding: Left inferior prefrontal cortex is still active. Anesthesiology 2008;109:213-224.
5. Veselis RA, Pryor KO, Reinsel RA, Li Y, Mehta M, Johnson R Jr. Propofol and midazolam inhibit conscious memory processes very soon after encoding: An event-related potential study of familiarity and recollection in volunteers. Anesthesiology 2009;110:295-312.
6. Pryor KO, Reinsel RA, Mehta M, Li Y, Wixted JT, Veselis RA. Visual P2-N2 complex and arousal at the time of encoding predict the time domain characteristics of amnesia for multiple intravenous anesthetic drugs in humans. Anesthesiology 2010;113:313-326.
7. Alkire MT, Guzowski JF. Hypothesis: Suppression of memory protein formation underlies anesthetic-induced amnesia. Anesthesiology 2008;109:768-770.
8. Burgess N, Maguire EA, O'Keefe J. The human hippocampus and spatial and episodic memory. Neuron 2002;35:625-641.
9. Crystal JD. Episodic-like memory in animals. Behav Brain Res 2010;215:235-243.
10. Neves G, Cooke SF, Bliss TV. Synaptic plasticity, memory and the hippocampus: A neural network approach to causality. Nat Rev Neurosci 2008;9:65-75.
11. Vorhees CV, Williams MT. Morris water maze: Procedures for assessing spatial and related forms of learning and memory. Nat Protoc 2006;1:848-858.
12. D'Hooge R, De Deyn PP. Applications of the Morris water maze in the study of learning and memory. Brain Res Brain Res Rev 2001;36:60-90.
13. Alberini CM. Transcription factors in long-term memory and synaptic plasticity. Physiol Rev 2009;89:121-145.
14. Barco A, Marie H. Genetic approaches to investigate the role of CREB in neuronal plasticity and memory. Mol Neurobiol 2011;44:330-349.
15. Nguyen PV. CREB and the enhancement of long-term memory. Trends Neurosci 2001;24:314.
16. Suzuki A, Fukushima H, Mukawa T, et al. Upregulation of CREB-mediated transcription enhances both short- and long-term memory. J Neurosci 2011;31:8786-8802.
17. Kawashima T, Okuno H, Nonaka M, et al. Synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons. Proc Natl Acad Sci U S A 2009;106:316-321.
18. Korb E, Finkbeiner S. Arc in synaptic plasticity: From gene to behavior. Trends Neurosci 2011;34:591-598.
19. Vecsey CG, Baillie GS, Jaganath D, et al. Sleep deprivation impairs cAMP signalling in the hippocampus. Nature 2009;461:1122-1125.
20. Barad M, Bourtchouladze R, Winder DG, Golan H, Kandel E. Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory. Proc Natl Acad Sci USA 1998;95:15020-15025.
21. Monti B, Berteotti C, Contestabile A. Subchronic rolipram delivery activates hippocampal CREB and arc, enhances retention and slows down extinction of conditioned fear. Neuropsychopharmacology 2006;31:278-286.
22. Alkire MT, Vazdarjanova A, Dickinson-Anson H, White NS, Cahill L. Lesions of the basolateral amygdala complex block propofol-induced amnesia for inhibitory avoidance learning in rats. Anesthesiology 2001;95:708-715.
23. Zhang HT, O'Donnell JM. Phosphodiesterase-4 as a pharmacological target mediating antidepressant and cognitive effects on behavior, Phosphodiesterases in Health and Disease. London, UK: CRC Press, 2007;539-558.
24. Giorgi M, Modica A, Pompili A, Pacitti C, Gasbarri A. The induction of cyclic nucleotide phosphodiesterase 4 gene (PDE4D) impairs memory in a water maze task. Behav Brain Res 2004;154:99-106.
25. Krause W, Kuhne G. Pharmacokinetics of rolipram in the rhesus and cynomolgus monkeys, the rat and the rabbit. Studies on species differences. Xenobiotica 1988;18:561-571.
26. Laalou FZ, de Vasconcelos AP, Oberling P, Jeltsch H, Cassel JC, Pain L. Involvement of the basal cholinergic forebrain in the mediation of general (propofol) anesthesia. Anesthesiology 2008;108:888-896.
27. Gamou S, Fukuda S, Ogura M, Sakamoto H, Morita S. Microinjection of propofol into the perifornical area induces sedation with decreasing cortical acetylcholine release in rats. Anesth Analg 2010;111:395-402.
28. Feldman LA, Shapiro ML, Nalbantoglu J. A novel, rapidly acquired and persistent spatial memory task that induces immediate early gene expression. Behav Brain Funct 2010;6:35.
29. Ward CP, McCarley RW, Strecker RE. Experimental sleep fragmentation impairs spatial reference but not working memory in Fischer/Brown Norway rats. J Sleep Res 2009;18:238-244.
30. Stanley JL, Lincoln RJ, Brown TA, McDonald LM, Dawson GR, Reynolds DS. The mouse beam walking assay offers improved sensitivity over the mouse rotarod in determining motor coordination deficits induced by benzodiazepines. J Psychopharmacol 2005;19:221-227.
31. Boix J, Cauli O, Felipo V. Developmental exposure to polychlorinated biphenyls 52, 138 or 180 affects differentially learning or motor coordination in adult rats. Mechanisms involved. Neuroscience 2010;167:994-1003.
32. Engeland CG, Vanderwolf CH, Gelb AW. Rats show unimpaired learning within minutes after recovery from single bolus propofol anesthesia. Can J Anaesth 1999;46:586-592.
33. Kurokawa H, Murray PA, Damron DS. Propofol attenuates beta-adrenoreceptor-mediated signal transduction via a protein kinase C-dependent pathway in cardiomyocytes. Anesthesiology 2002;96:688-698.
34. Kozinn J, Mao L, Arora A, Yang L, Fibuch EE, Wang JQ. Inhibition of glutamatergic activation of extracellular signal-regulated protein kinases in hippocampal neurons by the intravenous anesthetic propofol. Anesthesiology 2006;105:1182-1191.
35. Wang Y, Kikuchi T, Sakai M, Wu JL, Sato K, Okumura F. Age-related modifications of effects of ketamine and propofol on rat hippocampal acetylcholine release studied by in vivo brain microdialysis. Acta Anaesthesiol Scand 2000;44:112-117.
36. Florian C, Mons N, Roullet P. CREB antisense oligodeoxynucleotide administration into the dorsal hippocampal CA3 region impairs long- but not short-term spatial memory in mice. Learn Mem 2006;13:465-472.
37. Bernabeu R, Bevilaqua L, Ardenghi P, et al. Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats. Proc Natl Acad Sci USA 1997;94:7041-7046.
38. Kida S, Josselyn SA, Pena de Ortiz S, et al. CREB required for the stability of new and reactivated fear memories. Nat Neurosci 2002;5:348-355.
39. Vutskits L, Lysakowski C, Czarnetzki C, Jenny B, Copin JC, Tramer MR. Plasma concentrations of brain-derived neurotrophic factor in patients undergoing minor surgery: A randomized controlled trial. Neurochem Res 2008;33:1325-1331.
40. Linnarsson S, Björklund A, Ernfors P. Learning Deficit in BDNF Mutant Mice. Eur J Neurosci 1997;9:2581-2587.
41. Montkowski A, Holsboer F. Intact spatial learning and memory in transgenic mice with reduced BDNF. NeuroReport 1997;8:779-782.
42. Heldt SA, Stanek L, Chhatwal JP, Ressler KJ. Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories. Mol Psychiatry 2007;12:656-670.
43. Lu Y, Christian K, Lu B. BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory? Neurobiol Learn Mem 2008;89:312-323.
44. Guzowski JF, Lyford GL, Stevenson GD, et al. Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. J Neurosci 2000;20:3993-4001.
45. Grandoch M, Roscioni SS, Schmidt M. The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function. Br J Pharmacol 2010;159:265-284.
46. Yu X, Guo L, Yin G, Zong X, Ai Y. Effect of non-specific HCN1 blocker CsCl on spatial learning and memory in mouse. J Huazhong Univ Sci Technolog Med Sci 2006;26:164-166.
47. Perez-Torres S, Miro X, Palacios JM, Cortes R, Puigdomenech P, Mengod G. Phosphodiesterase type 4 isozymes expression in human brain examined by in situ hybridization histochemistry and[3H]rolipram binding autoradiography. Comparison with monkey and rat brain. J Chem Neuroanat 2000;20:349-374.
48. Ahmed T, Frey JU. Expression of the specific type IV phosphodiesterase gene PDE4B3 during different phases of long-term potentiation in single hippocampal slices of rats in vitro. Neuroscience 2003;117:627-638.
49. Sanou J, Ilboudo D, Goodall G, Bourdalle-Badie C, Erny P. Evaluation of cognitive functions after anesthesia with propofol. Ann Fr Anesth Reanim 1996;15:1155-1161.
50. Padmanabhan U, Leslie K, Eer AS, Maruff P, Silbert BS. Early cognitive impairment after sedation for colonoscopy: The effect of adding midazolam and/or fentanyl to propofol. Anesth Analg 2009;109:1448-1455.
51. Collado MC, Beleta J, Martinez E, et al. Functional and biochemical evidence for diazepam as a cyclic nucleotide phosphodiesterase type 4 inhibitor. Br J Pharmacol 1998;123:1047-1054.