Hydrogen peroxide inhibits transforming growth factor-β1-induced cell cycle arrest by promoting Smad3 linker phosphorylation through activation of Akt-ERK1/2-linked signaling pathway

Biochemical and Biophysical Research Communications

Volumn 435, Issue 4, 2013, Pages 634-639

  Choi, Jiyeon ^a   Park, Seong Ji ^a   Jo, Eun Ji ^a   Lee, Hui Young ^a   Hong, Suntaek ^b   Kim, Seong Jin ^c   Kim, Byung Chul ^a  

^a Kangwon National University   (South Korea)

^b Gachon University   (South Korea)

^c CHA University   (South Korea)

Author keywords

Growth inhibition; H2O2; Smad3 linker phosphorylation; TGF 1

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2,3 DIHYDRO 2 OXO 3 (4,5,6,7 TETRAHYDRO 1H INDOL 2 YLMETHYLENE) 1H INDOLE 5 SULFONIC ACID DIMETHYLAMIDE; 4 (4 FLUOROPHENYL) 2 (4 NITROPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CALPHOSTIN C; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN INHIBITOR; PROTEIN KINASE B; PROTEIN P15; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VIRUS VECTOR; XMD 892;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOSTASIS; DNA TRANSFECTION; ENZYME ACTIVATION; GENE INDUCTION; GROWTH INHIBITION; HEPATOBLASTOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; CELL CYCLE CHECKPOINTS; ENZYME ACTIVATION; HEP G2 CELLS; HUMANS; HYDROGEN PEROXIDE; MAP KINASE SIGNALING SYSTEM; MINK; PHOSPHORYLATION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84878994375     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.05.035     Document Type: Article

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