Phosphoinositide 3-kinase/Akt signaling is essential for prostaglandin E2-induced osteogenic differentiation of rat tendon stem cells

Biochemical and Biophysical Research Communications

Volumn 435, Issue 4, 2013, Pages 514-519

  Liu, Junpeng ^a   Chen, Lei ^a   Tao, Xu ^a   Tang, Kanglai ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Bone morphogenetic protein 2; Osteoblast differentiation; Phosphoinositide 3 kinase Akt signaling; Prostaglandin E2; Tendon stem cells

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; OSTEOCALCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E2; PROTEIN KINASE B; SMAD PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; STAGE SPECIFIC EMBRYO ANTIGEN 4; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; EXTRACELLULAR MATRIX; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; STEM CELL; TENDON STEM CELL; UPREGULATION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; CELLS, CULTURED; DINOPROSTONE; OSTEOGENESIS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STEM CELLS; TENDONS;

RATTUS;

EID: 84878987506     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.11.083     Document Type: Article

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