Stearidonic and γ-linolenic acids in echium oil improves glucose disposal in insulin resistant monkeys

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 89, Issue 1, 2013, Pages 39-45

  Kavanagh, K ^a   Flynn, D M ^a   Jenkins, K A ^a   Wilson, M D ^a   Chilton, F H ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Diabetes; Echium oil; Fish oil; Gamma Linolenic acid; Polyunsaturated fatty acids; Stearidonic acid

Indexed keywords

BIOLOGICAL MARKER; DIHOMO GAMMA LINOLENIC ACID; ECHIUM OIL; FISH OIL; GAMMA LINOLENIC ACID; GLUCOSE; OIL; POLYUNSATURATED FATTY ACID; SAFFLOWER OIL; STEARIDONIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOACCUMULATION; CARDIOVASCULAR DISEASE; CHLOROCEBUS; CONTROLLED STUDY; DIABETES MELLITUS; DIET SUPPLEMENTATION; DISEASE MARKER; ERYTHROCYTE; FATTY ACID ANALYSIS; FATTY ACID BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; INSULIN RESISTANCE; LIPID COMPOSITION; MUSCLE LEVEL; NONHUMAN; PRIORITY JOURNAL; THERAPY EFFECT;

ANIMALS; ECHIUM; ERYTHROCYTES; FATTY ACIDS, OMEGA-3; FATTY ACIDS, UNSATURATED; GAMMA-LINOLENIC ACID; GLUCOSE; HAPLORHINI; INSULIN RESISTANCE; MUSCLE, SKELETAL; PLANT OILS;

CARTHAMUS TINCTORIUS; CERCOPITHECUS AETHIOPS; ECHIUM;

EID: 84878982475     PISSN: 09523278     EISSN: 15322823     Source Type: Journal    
DOI: 10.1016/j.plefa.2013.04.003     Document Type: Article

References (43)

1. Knowler W.C., Barrett-Connor E., Fowler S.E., Hamman R.F., Lachin J.M., Walker E.A., Nathan D.M. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med. 2002, 346:393-403.
2. McAuley K.A., Williams S.M., Mann J.I., Goulding A., Chisholm A., Wilson N., Story G., McLay R.T., Harper M.J., Jones I.E. Intensive lifestyle changes are necessary to improve insulin sensitivity: a randomized controlled trial. Diabetes Care 2002, 25:445-452.
3. Karlstrom B.E., Jarvi A.E., Byberg L., Berglund L.G., Vessby B.O. Fatty fish in the diet of patients with type 2 diabetes: comparison of the metabolic effects of foods rich in n-3 and n-6 fatty acids. Am. J. Clin. Nutr. 2011, 94:26-33.
4. Djousse L., Biggs M.L., Lemaitre R.N., King I.B., Song X., Ix J.H., Mukamal K.J., Siscovick D.S., Mozaffarian D. Plasma omega-3 fatty acids and incident diabetes in older adults. Am. J. Clin. Nutr. 2011, 94:527-533.
5. Meyer K.A., Kushi L.H., Jacobs D.R. Folsom AR: dietary fat and incidence of type 2 diabetes in older iowa women. Diabetes Care 2001, 24:1528-1535.
6. Montori V.M., Farmer A., Wollan P.C., Dinneen S.F. Fish oil supplementation in type 2 diabetes: a quantitative systematic review. Diabetes Care 2000, 23:1407-1415.
7. Villegas R., Xiang Y.B., Elasy T., Li H.L., Yang G., Cai H., Ye F., Gao Y.T., Shyr Y., Zheng W., Shu X.O. Fish, shellfish, and long-chain n-3 fatty acid consumption and risk of incident type 2 diabetes in middle-aged Chinese men and women. Am. J. Clin. Nutr. 2011, 94:543-551.
8. Giacco R., Cuomo V., Vessby B., Uusitupa M., Hermansen K., Meyer B.J., Riccardi G., Rivellese A.A. Fish oil, insulin sensitivity, insulin secretion and glucose tolerance in healthy people: is there any effect of fish oil supplementation in relation to the type of background diet and habitual dietary intake of n-6 and n-3 fatty acids?. Nutr. Metab. Cardiovasc. Dis. 2007, 17:572-580.
9. Iggman D., Arnlov J., Vessby B., Cederholm T., Sjogren P., Riserus U. Adipose tissue fatty acids and insulin sensitivity in elderly men. Diabetologia 2010, 53:850-857.
10. Krachler B., Norberg M., Eriksson J.W., Hallmans G., Johansson I., Vessby B., Weinehall L., Lindahl B. Fatty acid profile of the erythrocyte membrane preceding development of type 2 diabetes mellitus. Nutr. Metab. Cardiovasc. Dis. 2008, 18:503-510.
11. Bosch J., Gerstein H.C., Dagenais G.R., Diaz R., Dyal L., Jung H., Maggiono A.P., Probstfield J., Ramachandran A., Riddle M.C., Ryden L.E., Yusuf S. N-3 fatty acids and cardiovascular outcomes in patients with dysglycemia. N. Engl. J. Med. 2012, 367:309-318.
12. Mori T.A., Woodman R.J., Burke V., Puddey I.B., Croft K.D., Beilin L.J. Effect of eicosapentaenoic acid and docosahexaenoic acid on oxidative stress and inflammatory markers in treated-hypertensive type 2 diabetic subjects. Free Radic. Biol. Med. 2003, 35:772-781.
13. Mantzioris E., James M.J., Gibson R.A., Cleland L.G. Dietary substitution with an alpha-linolenic acid-rich vegetable oil increases eicosapentaenoic acid concentrations in tissues. Am. J. Clin. Nutr. 1994, 59:1304-1309.
14. Huang Y.S., Smith R.S., Redden P.R., Cantrill R.C., Horrobin D.F. Modification of liver fatty acid metabolism in mice by n-3 and n-6 delta 6-desaturase substrates and products. Biochim. Biophys. Acta 1991, 1082:319-327.
15. Yamazaki K., Fujikawa M., Hamazaki T., Yano S., Shono T. Comparison of the conversion rates of alpha-linolenic acid (18:3(n-3)) and stearidonic acid (18:4(n-3)) to longer polyunsaturated fatty acids in rats. Biochim. Biophys. Acta 1992, 1123:18-26.
16. Surette M.E., Edens M., Chilton F.H., Tramposch K.M. Dietary echium oil increases plasma and neutrophil long-chain (n-3) fatty acids and lowers serum triacylglycerols in hypertriglyceridemic humans. J. Nutr. 2004, 134:1406-1411.
17. Whelan J., Gouffon J., Zhao Y. Effects of dietary stearidonic acid on biomarkers of lipid metabolism. J. Nutr. 2012, 142:630S-634S.
18. James M.J., Ursin V.M., Cleland L.G. Metabolism of stearidonic acid in human subjects: comparison with the metabolism of other n-3 fatty acids. Am. J. Clin. Nutr. 2003, 77:1140-1145.
19. Metcalfe L.D.S.A., Pelka J.R. Rapid preparation of fatty acid esters from lipid gas chromatography analysis. Anal. Chem. 1966, 38:514-515.
20. Hotamisligil G.S., Murray D.L., Choy L.N., Spiegelman B.M. Tumor necrosis factor alpha inhibits signaling from the insulin receptor. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:4854-4858.
21. Hotamisligil G.S., Peraldi P., Budavari A., Ellis R., White M.F., Spiegelman B.M. Irs-1-mediated inhibition of insulin receptor tyrosine kinase activity in tnf-alpha- and obesity-induced insulin resistance. Science 1996, 271:665-668.
22. Wu J.H., Micha R., Imamura F., Pan A., Biggs M.L., Ajaz O., Djousse L.F.B.H., Mozaffarian D. Omega-3 fatty acids and incident type 2 diabetes: a systematic review and meta-analysis. Br J Nutr. 2012, 107(2):S214-227.
23. Brown A.L., Zhu X., Rong S., Shewale S., Seo J., Boudyguina E., Gebre A.K., Alexander-Miller M.A., Parks J.S. Omega-3 fatty acids ameliorate atherosclerosis by favorably altering monocyte subsets and limiting monocyte recruitment to aortic lesions. Arterioscler. Thromb. Vasc. Biol. 2012, 32:2122-2130.
24. Pacht E.R., DeMichele S.J., Nelson J.L., Hart J., Wennberg A.K., Gadek J.E. Enteral nutrition with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome. Crit Care Med. 2003, 31:491-500.
25. Surette M.E., Koumenis I.L., Edens M.B., Tramposch K.M., Chilton F.H. Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects. Clin. Ther. 2003, 25:948-971.
26. Weaver K.L., Ivester P., Seeds M., Case L.D., Arm J.P., Chilton F.H. Effect of dietary fatty acids on inflammatory gene expression in healthy humans. J. Biol. Chem. 2009, 284:15400-15407.
27. Kapoor R., Huang Y.S. Gamma linolenic acid: an antiinflammatory omega-6 fatty acid. Curr. Pharm. Biotechnol. 2006, 7:531-534.
28. Arisaka M., Arisaka O., Yamashiro Y. Fatty acid and prostaglandin metabolism in children with diabetes mellitus. II. The effect of evening primrose oil supplementation on serum fatty acid and plasma prostaglandin levels. Prostaglandins Leukot. Essent. Fatty Acids 1991, 43:197-201.
29. Takai S., Jin D., Kawashima H., Kimura M., Shiraishi-Tateishi A., Tanaka T., Kakutani S., Tanaka K., Kiso Y., Miyazaki M. Anti-atherosclerotic effects of dihomo-gamma-linolenic acid in apoe-deficient mice. J. Atheroscler. Thromb. 2009, 16:480-489.
30. Jones D.A., Fitzpatrick F.A. Suicide Inactivation of thromboxane a2 synthase. Characteristics of mechanism-based inactivation with isolated enzyme and intact platelets. J. Biol. Chem. 1990, 265:20166-20171.
31. Chopra J., Webster R.O. Pge1 inhibits neutrophil adherence and neutrophil-mediated injury to cultured endothelial cells. Am. Rev. Respir. Dis. 1988, 138:915-920.
32. Abraham E., Park Y.C., Covington P., Conrad S.A., Schwartz M. Liposomal prostaglandin e1 in acute respiratory distress syndrome: a placebo-controlled, randomized, double-blind, multicenter clinical trial. Crit. Care Med. 1996, 24:10-15.
33. Palombo J.D., DeMichele S.J., Boyce P.J., Lydon E.E., Liu J.W., Huang Y.S., Forse R.A., Mizgerd J.P., Bistrian B.R. Effect of short-term enteral feeding with eicosapentaenoic and gamma-linolenic acids on alveolar macrophage eicosanoid synthesis and bactericidal function in rats. Crit. Care Med. 1999, 27:1908-1915.
34. Andreassi M., Forleo P., Di Lorio A., Masci S., Abate G., Amerio P. Efficacy of gamma-linolenic acid in the treatment of patients with atopic dermatitis. J. Int. Med. Res. 1997, 25:266-274.
35. Henz B.M., Jablonska S., van de Kerkhof P.C., Stingl G., Blaszczyk M., Vandervalk P.G., Veenhuizen R., Muggli R., Raederstorff D. Double-blind, multicentre analysis of the efficacy of borage oil in patients with atopic eczema. Br. J. Dermatol. 1999, 140:685-688.
36. Zurier R.B., Rossetti R.G., Jacobson E.W., DeMarco D.M., Liu N.Y., Temming J.E., White B.M., Laposata M. Gamma-linolenic acid treatment of rheumatoid arthritis. A randomized, placebo-controlled trial. Arthritis Rheum. 1996, 39:1808-1817.
37. Khamaisi M., Rudich A., Beeri I., Pessler D., Friger M., Gavrilov V., Tritschler H., Bashan N. Metabolic effects of gamma-linolenic acid-alpha-lipoic acid conjugate in streptozotocin diabetic rats. Antioxid. Redox Signal 1999, 1:523-535.
38. Takahashi Y., Ide T., Fujita H. Dietary gamma-linolenic acid in the form of borage oil causes less body fat accumulation accompanying an increase in uncoupling protein 1 mrna level in brown adipose tissue. Comp. Biochem. Physiol. B Biochem. Mol Biol. 2000, 127:213-222.
39. Sergeant S., Hugenschmidt C.E., Rudock M.E., Ziegler J.T., Ivester P., Ainsworth H.C., Vaidya D., Case L.D., Langefeld C.D., Freedman B.I., Bowden D.W., Mathias R.A., Chilton F.H. Differences in arachidonic acid levels and fatty acid desaturase (fads) gene variants in african americans and european americans with diabetes or the metabolic syndrome. Br. J. Nutr. 2012, 107:547-555.
40. Forrest L.M., Boudyguina E., Wilson M.D., Parks J.S. Echium oil reduces atherosclerosis in apob100-only LDLrKO mice. Atherosclerosis 2012, 220:118-121.
41. Zhang P., Boudyguina E., Wilson M.D., Gebre A.K., Parks J.S. Echium oil reduces plasma lipids and hepatic lipogenic gene expression in apob100-only LDL receptor knockout mice. J. Nutr. Biochem. 2008, 19:655-663.
42. Lemke S.L., Vicini J.L., Su H., Goldstein D.A., Nemeth M.A., Krul E.S., Harris W.S. Dietary intake of stearidonic acid-enriched soybean oil increases the omega-3 index: randomized, double-blind clinical study of efficacy and safety. Am. J. Clin. Nutr. 2010, 92:766-775.
43. Kitessa S.M., Young P., Nattrass G., Gardner G., Pearce K., Pethick D.W. When balanced for precursor fatty acid supply echium oil is not superior to linseed oil in enriching lamb tissues with long-chain n-3 pufa. Br. J. Nutr. 2011, 1-9.