메뉴 건너뛰기




Volumn 33, Issue 11, 2013, Pages 2260-2274

MicroRNA 9-3p targets β1 integrin to sensitize claudin-low breast cancer cells to MEK inhibition

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CLAUDIN; MICRORNA 9; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; SELUMETINIB; SMALL INTERFERING RNA; TRAMETINIB;

EID: 84878980752     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00269-13     Document Type: Article
Times cited : (47)

References (60)
  • 4
    • 65949106827 scopus 로고    scopus 로고
    • The plasticity of oncogene addiction: implications for targeted therapies directed to receptor tyrosine kinases
    • 2 p following 458
    • Pillay V, Allaf L, Wilding AL, Donoghue JF, Court NW, Greenall SA, Scott AM, Johns TG. 2009. The plasticity of oncogene addiction: implications for targeted therapies directed to receptor tyrosine kinases. Neoplasia 11:448-458, 2 p following 458.
    • (2009) Neoplasia , vol.11 , pp. 448-458
    • Pillay, V.1    Allaf, L.2    Wilding, A.L.3    Donoghue, J.F.4    Court, N.W.5    Greenall, S.A.6    Scott, A.M.7    Johns, T.G.8
  • 5
    • 79952654970 scopus 로고    scopus 로고
    • Molecular stratification of triple-negative breast cancers
    • Perou CM. 2010. Molecular stratification of triple-negative breast cancers. Oncologist 15(Suppl. 5):39-48.
    • (2010) Oncologist , vol.15 , Issue.SUPPL. 5 , pp. 39-48
    • Perou, C.M.1
  • 11
    • 77249135213 scopus 로고    scopus 로고
    • Three-dimensional overlay culture models of human breast cancer reveal a critical sensitivity to mitogenactivated protein kinase kinase inhibitors
    • Li Q, Chow AB, Mattingly RR. 2010. Three-dimensional overlay culture models of human breast cancer reveal a critical sensitivity to mitogenactivated protein kinase kinase inhibitors. J. Pharmacol. Exp. Ther. 332: 821-828.
    • (2010) J. Pharmacol. Exp. Ther. , vol.332 , pp. 821-828
    • Li, Q.1    Chow, A.B.2    Mattingly, R.R.3
  • 20
    • 0034306997 scopus 로고    scopus 로고
    • Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
    • Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR. 2000. Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev. 14:2501-2514.
    • (2000) Genes Dev. , vol.14 , pp. 2501-2514
    • Sears, R.1    Nuckolls, F.2    Haura, E.3    Taya, Y.4    Tamai, K.5    Nevins, J.R.6
  • 27
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: a sensitive and quantitative DNA methylation assay
    • Xiong Z, Laird PW. 1997. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res. 25:2532-2534.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2
  • 28
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network.
    • Cancer Genome Atlas Network. 2012. Comprehensive molecular portraits of human breast tumours. Nature 490:61-70.
    • (2012) Nature , vol.490 , pp. 61-70
  • 29
    • 0024335963 scopus 로고
    • Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression
    • Werb Z, Tremble PM, Behrendtsen O, Crowley E, Damsky CH. 1989. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J. Cell Biol. 109:877-889.
    • (1989) J. Cell Biol. , vol.109 , pp. 877-889
    • Werb, Z.1    Tremble, P.M.2    Behrendtsen, O.3    Crowley, E.4    Damsky, C.H.5
  • 30
    • 79951938163 scopus 로고    scopus 로고
    • DNA methylation of tumor suppressor miRNA genes: a lesson from the miR-34 family
    • Wong KY, Yu L, Chim CS. 2011. DNA methylation of tumor suppressor miRNA genes: a lesson from the miR-34 family. Epigenomics 3:83-92.
    • (2011) Epigenomics , vol.3 , pp. 83-92
    • Wong, K.Y.1    Yu, L.2    Chim, C.S.3
  • 31
    • 79960075244 scopus 로고    scopus 로고
    • MicroRNA-9: functional evolution of a conserved small regulatory RNA
    • Yuva-Aydemir Y, Simkin A, Gascon E, Gao F-B. 2011. MicroRNA-9: functional evolution of a conserved small regulatory RNA. RNA Biol. 8:557-564.
    • (2011) RNA Biol. , vol.8 , pp. 557-564
    • Yuva-Aydemir, Y.1    Simkin, A.2    Gascon, E.3    Gao, F.-B.4
  • 32
    • 79952267171 scopus 로고    scopus 로고
    • MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors
    • Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S. 2011. MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J. Neurosci. 31:3407-3422.
    • (2011) J. Neurosci. , vol.31 , pp. 3407-3422
    • Shibata, M.1    Nakao, H.2    Kiyonari, H.3    Abe, T.4    Aizawa, S.5
  • 33
    • 78651425546 scopus 로고    scopus 로고
    • MicroRNA-9 reveals regional diversity of neural progenitors along the anterior-posterior axis
    • Bonev B, Pisco A, Papalopulu N. 2011. MicroRNA-9 reveals regional diversity of neural progenitors along the anterior-posterior axis. Dev. Cell 20:19-32.
    • (2011) Dev. Cell , vol.20 , pp. 19-32
    • Bonev, B.1    Pisco, A.2    Papalopulu, N.3
  • 35
    • 78649832226 scopus 로고    scopus 로고
    • A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation
    • Laneve P, Gioia U, Andriotto A, Moretti F, Bozzoni I, Caffarelli E. 2010. A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation. Nucleic Acids Res. 38:6895-6905.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 6895-6905
    • Laneve, P.1    Gioia, U.2    Andriotto, A.3    Moretti, F.4    Bozzoni, I.5    Caffarelli, E.6
  • 36
    • 58149375393 scopus 로고    scopus 로고
    • The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease
    • Packer AN, Xing Y, Harper SQ, Jones L, Davidson BL. 2008. The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. J. Neurosci. 28:14341-14346.
    • (2008) J. Neurosci. , vol.28 , pp. 14341-14346
    • Packer, A.N.1    Xing, Y.2    Harper, S.Q.3    Jones, L.4    Davidson, B.L.5
  • 38
    • 81855224576 scopus 로고    scopus 로고
    • Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy
    • Kasinski AL, Slack FJ. 2011. Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat. Rev. Cancer 11:849-864.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 849-864
    • Kasinski, A.L.1    Slack, F.J.2
  • 40
    • 80052870189 scopus 로고    scopus 로고
    • Differential micro-RNA expression in primary CNS and nodal diffuse large B-cell lymphomas
    • Fischer L, Hummel M, Korfel A, Lenze D, Joehrens K, Thiel E. 2011. Differential micro-RNA expression in primary CNS and nodal diffuse large B-cell lymphomas. Neuro. Oncol. 13:1090-1098.
    • (2011) Neuro. Oncol. , vol.13 , pp. 1090-1098
    • Fischer, L.1    Hummel, M.2    Korfel, A.3    Lenze, D.4    Joehrens, K.5    Thiel, E.6
  • 41
    • 84860746857 scopus 로고    scopus 로고
    • Clinicopathological and prognostic significance of microRNA-107 and its relationship to DICER1 mRNA expression in gastric cancer
    • Inoue T, Iinuma H, Ogawa E, Inaba T, Fukushima R. 2012. Clinicopathological and prognostic significance of microRNA-107 and its relationship to DICER1 mRNA expression in gastric cancer. Oncol. Rep. 27: 1759-1764.
    • (2012) Oncol. Rep. , vol.27 , pp. 1759-1764
    • Inoue, T.1    Iinuma, H.2    Ogawa, E.3    Inaba, T.4    Fukushima, R.5
  • 42
    • 78650668809 scopus 로고    scopus 로고
    • miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells
    • Zhou H, Huang X, Cui H, Luo X, Tang Y, Chen S, Wu L, Shen N. 2010. miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells. Blood 116: 5885-5894.
    • (2010) Blood , vol.116 , pp. 5885-5894
    • Zhou, H.1    Huang, X.2    Cui, H.3    Luo, X.4    Tang, Y.5    Chen, S.6    Wu, L.7    Shen, N.8
  • 44
    • 59449094255 scopus 로고    scopus 로고
    • Volociximab, a chimeric monoclonal antibody that specifically binds alpha5beta1 integrin: a phase I, pharmacokinetic, and biological correlative study
    • Ricart AD, Tolcher AW, Liu G, Holen K, Schwartz G, Albertini M, Weiss G, Yazji S, Ng C, Wilding G. 2008. Volociximab, a chimeric monoclonal antibody that specifically binds alpha5beta1 integrin: a phase I, pharmacokinetic, and biological correlative study. Clin. Cancer Res. 14:7924-7929.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 7924-7929
    • Ricart, A.D.1    Tolcher, A.W.2    Liu, G.3    Holen, K.4    Schwartz, G.5    Albertini, M.6    Weiss, G.7    Yazji, S.8    Ng, C.9    Wilding, G.10
  • 47
    • 0037457423 scopus 로고    scopus 로고
    • Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice
    • Stoeltzing O, Liu W, Reinmuth N, Fan F, Parry GC, Parikh AA, McCarty MF, Bucana CD, Mazar AP, Ellis LM. 2003. Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice. Int. J. Cancer 104:496-503.
    • (2003) Int. J. Cancer , vol.104 , pp. 496-503
    • Stoeltzing, O.1    Liu, W.2    Reinmuth, N.3    Fan, F.4    Parry, G.C.5    Parikh, A.A.6    McCarty, M.F.7    Bucana, C.D.8    Mazar, A.P.9    Ellis, L.M.10
  • 49
    • 70350731216 scopus 로고    scopus 로고
    • Preclinical evaluation of the novel smallmolecule integrin alpha5beta1 inhibitor JSM6427 in monkey and rabbit models of choroidal neovascularization
    • Zahn G, Vossmeyer D, Stragies R, Wills M, Wong CG, Löffler KU, Adamis AP, Knolle J. 2009. Preclinical evaluation of the novel smallmolecule integrin alpha5beta1 inhibitor JSM6427 in monkey and rabbit models of choroidal neovascularization. Arch. Ophthalmol. 127:1329-1335.
    • (2009) Arch. Ophthalmol. , vol.127 , pp. 1329-1335
    • Zahn, G.1    Vossmeyer, D.2    Stragies, R.3    Wills, M.4    Wong, C.G.5    Löffler, K.U.6    Adamis, A.P.7    Knolle, J.8
  • 51
    • 0034744538 scopus 로고    scopus 로고
    • Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEKextracellular signal-regulated kinase signaling pathway
    • Woods D, Cherwinski H, Venetsanakos E, Bhat A, Gysin S, Humbert M, Bray PF, Saylor VL, McMahon M. 2001. Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEKextracellular signal-regulated kinase signaling pathway. Mol. Cell. Biol. 21:3192-3205.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3192-3205
    • Woods, D.1    Cherwinski, H.2    Venetsanakos, E.3    Bhat, A.4    Gysin, S.5    Humbert, M.6    Bray, P.F.7    Saylor, V.L.8    McMahon, M.9
  • 52
    • 0002460807 scopus 로고    scopus 로고
    • Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling
    • Aguirre Ghiso JA, Kovalski K, Ossowski L. 1999. Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling. J. Cell Biol. 147:89-104.
    • (1999) J. Cell Biol. , vol.147 , pp. 89-104
    • Aguirre Ghiso, J.A.1    Kovalski, K.2    Ossowski, L.3
  • 56
    • 0032487829 scopus 로고    scopus 로고
    • Amplification of Ki-ras and elevation of MAP kinase activity during mammary tumor progression in C3(1)/SV40 Tag transgenic mice
    • Liu ML, Von Lintig FC, Liyanage M, Shibata MA, Jorcyk CL, Ried T, Boss GR, Green JE. 1998. Amplification of Ki-ras and elevation of MAP kinase activity during mammary tumor progression in C3(1)/SV40 Tag transgenic mice. Oncogene 17:2403-2411.
    • (1998) Oncogene , vol.17 , pp. 2403-2411
    • Liu, M.L.1    Von Lintig, F.C.2    Liyanage, M.3    Shibata, M.A.4    Jorcyk, C.L.5    Ried, T.6    Boss, G.R.7    Green, J.E.8
  • 59
    • 33845981503 scopus 로고    scopus 로고
    • Novel c-MYC target genes mediate differential effects on cell proliferation and migration
    • Cappellen D, Schlange T, Bauer M, Maurer F, Hynes NE. 2007. Novel c-MYC target genes mediate differential effects on cell proliferation and migration. EMBO Rep. 8:70-76.
    • (2007) EMBO Rep. , vol.8 , pp. 70-76
    • Cappellen, D.1    Schlange, T.2    Bauer, M.3    Maurer, F.4    Hynes, N.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.