Hollow fiber based affinity selection combined with high performance liquid chromatography-mass spectroscopy for rapid screening lipase inhibitors from lotus leaf

Analytica Chimica Acta

Volumn 785, Issue , 2013, Pages 75-81

  Tao, Yi ^a   Zhang, Yufeng ^a   Wang, Yi ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Hollow fiber; Indirect affinity selection mass spectrometry screening; Lipase inhibitor; Lotus leaf; Medicinal plants

Indexed keywords

AFFINITY SELECTION; BINDING CAPABILITY; ENZYME CONCENTRATIONS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRIES; HOLLOW FIBER; LOTUS LEAF; MEDICINAL PLANTS; POLYPROPYLENE HOLLOW FIBER;

CHROMATOGRAPHY; DRUG PRODUCTS; FATTY ACIDS; FIBERS; FLAVONOIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIGANDS; MASS SPECTROMETRY; PHENOLS; PLANTS (BOTANY); POLYPROPYLENES;

LIPASES;

ENZYME INHIBITOR; FLAVONOID; HESPERIDIN; KAEMPFEROL 3 O BETA DEXTRO GLUCURONIDE; LIPASE INHIBITOR; QUERCETIN 3 O BETA DEXTRO ARABINOPYRANOSYL (1-2) BETA DEXTRO GALACTOPYRANOSIDE; QUERCETIN 3 O BETA DEXTRO GLUCURONIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; ENZYME BINDING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOLLOW FIBER; INCUBATION TIME; IONIC STRENGTH; LIGAND BINDING; LOTUS; MASS SPECTROMETRY; PH; PHASE SEPARATION; PLANT LEAF; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; TEMPERATURE SENSITIVITY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; ENZYMES, IMMOBILIZED; FLAVONOIDS; HESPERIDIN; HYDROGEN-ION CONCENTRATION; LIPASE; LOTUS; OSMOLAR CONCENTRATION; PLANT LEAVES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

SUS;

EID: 84878971537     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2013.04.058     Document Type: Article

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