Direct affinity screening chromatography-mass spectrometry assay for identification of antibacterial agents from natural product sources

Analytica Chimica Acta

Volumn 713, Issue , 2012, Pages 103-110

  Schug, Kevin A ^a   Wang, Evelyn ^a   Shen, Sijia ^a   Rao, Sunaina ^a   Smith, Stephanie M ^a   Hunt, Laura ^a   Mydlarz, Laura D ^a  

^a UNIVERSITY OF TEXAS AT ARLINGTON   (United States)

Author keywords

Dynamic titration; Electrospray ionization; Natural products; Noncovalent interactions; Pseudoplexaura porosa

Indexed keywords

ANTIBACTERIAL AGENT; CHROMATOGRAPHY-MASS SPECTROMETRY; DRUG DISCOVERY; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; ELECTROSPRAYS; FLOW INJECTION; GRAM POSITIVE BACTERIAL CELLS; NATURAL PRODUCTS; NEGATIVE CONTROL; NEW CHEMICAL ENTITIES; NON-COVALENT COMPLEXES; NON-COVALENT INTERACTION; PROOF OF PRINCIPLES; PSEUDOPLEXAURA POROSA;

AMINO ACIDS; CELL MEMBRANES; DRUG INTERACTIONS; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; TITRATION;

ELECTROSPRAY IONIZATION;

ANTIINFECTIVE AGENT; CHLORAMPHENICOL; GENTAMICIN; NATURAL PRODUCT; NEOMYCIN; PSEUDOPLEXAURA POROSA EXTRACT; RISTOCETIN; SPECTINOMYCIN; TEICOPLANIN; TETRACYCLINE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; CONTROLLED STUDY; CORAL; DRUG BINDING; DRUG DETERMINATION; DRUG ISOLATION; ELECTROSPRAY MASS SPECTROMETRY; FLOW INJECTION ANALYSIS; FRACTIONATION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PSEUDOPLEXAURA POROSA; QUANTITATIVE STUDY; SCREENING TEST; TITRIMETRY; VALIDATION PROCESS;

ALANINE; ANIMALS; ANTHOZOA; ANTI-BACTERIAL AGENTS; BIOLOGICAL AGENTS; CHROMATOGRAPHY, AFFINITY; GRAM-POSITIVE BACTERIA; LYSINE; OLIGOPEPTIDES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

ANTHOZOA; BACTERIA (MICROORGANISMS); GORGONIA; POSIBACTERIA; PSEUDOPLEXAURA POROSA;

EID: 84855186868     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2011.11.038     Document Type: Article

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