메뉴 건너뛰기




Volumn 220, Issue 2, 2013, Pages 172-180

The Fusarium toxin deoxynivalenol (DON) modulates the LPS induced acute phase reaction in pigs

Author keywords

Acute phase reaction; Acute phase response; Clinical signs; Cytokines; Deoxynivalenol; Lipopolysaccharide; Pathophysiology; Pig

Indexed keywords

BILIRUBIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; VOMITOXIN;

EID: 84878964961     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.04.005     Document Type: Article
Times cited : (16)

References (35)
  • 2
    • 0026098115 scopus 로고
    • Plasma concentrations of endotoxin following jugular or portal injections of endotoxin and following gastrointestinal ischemia due to hemorrhage
    • Bottoms G.D., Gimarc S., Pfeifer C. Plasma concentrations of endotoxin following jugular or portal injections of endotoxin and following gastrointestinal ischemia due to hemorrhage. Circulatory Shock 1991, 33:1-6.
    • (1991) Circulatory Shock , vol.33 , pp. 1-6
    • Bottoms, G.D.1    Gimarc, S.2    Pfeifer, C.3
  • 3
    • 0019501763 scopus 로고
    • Measurement of zinc flux through plasma in normal and endotoxin-stressed pigs and the effects of Zn supplementation during stress
    • Chesters J.K., Will M. Measurement of zinc flux through plasma in normal and endotoxin-stressed pigs and the effects of Zn supplementation during stress. British Journal of Nutrition 1981, 46:119-130.
    • (1981) British Journal of Nutrition , vol.46 , pp. 119-130
    • Chesters, J.K.1    Will, M.2
  • 5
    • 79952158502 scopus 로고    scopus 로고
    • Vulnerability of polarised intestinal porcine epithelial cells to mycotoxin deoxynivalenol depends on the route of application
    • Diesing A.K., Nossol C., Dänicke S., Walk N., Post A., Kahlert S., Rothkötter H.J., Kluess J. Vulnerability of polarised intestinal porcine epithelial cells to mycotoxin deoxynivalenol depends on the route of application. PLoS ONE 2011, 6:e17472.
    • (2011) PLoS ONE , vol.6
    • Diesing, A.K.1    Nossol, C.2    Dänicke, S.3    Walk, N.4    Post, A.5    Kahlert, S.6    Rothkötter, H.J.7    Kluess, J.8
  • 6
    • 80053603016 scopus 로고    scopus 로고
    • The Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) in animal feeding
    • Döll S., Dänicke S. The Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) in animal feeding. Preventive Veterinary Medicine 2011, 102:132-145.
    • (2011) Preventive Veterinary Medicine , vol.102 , pp. 132-145
    • Döll, S.1    Dänicke, S.2
  • 7
    • 58149279284 scopus 로고    scopus 로고
    • Deoxynivalenol-induced cytotoxicity, cytokines and related genes in unstimulated or lipopolysaccharide stimulated primary porcine macrophages
    • Döll S., Schrickx J.A., Dänicke S., Fink-Gremmels J. Deoxynivalenol-induced cytotoxicity, cytokines and related genes in unstimulated or lipopolysaccharide stimulated primary porcine macrophages. Toxicology Letters 2009, 184:97-106.
    • (2009) Toxicology Letters , vol.184 , pp. 97-106
    • Döll, S.1    Schrickx, J.A.2    Dänicke, S.3    Fink-Gremmels, J.4
  • 8
    • 68349144573 scopus 로고    scopus 로고
    • Interactions of deoxynivalenol and lipopolysaccharides on cytokine excretion and mRNA expression in porcine hepatocytes and Kupffer cell enriched hepatocyte cultures
    • Döll S., Schrickx J.A., Dänicke S., Fink-Gremmels J. Interactions of deoxynivalenol and lipopolysaccharides on cytokine excretion and mRNA expression in porcine hepatocytes and Kupffer cell enriched hepatocyte cultures. Toxicology Letters 2009, 190:96-105.
    • (2009) Toxicology Letters , vol.190 , pp. 96-105
    • Döll, S.1    Schrickx, J.A.2    Dänicke, S.3    Fink-Gremmels, J.4
  • 9
    • 8844247487 scopus 로고    scopus 로고
    • Opinion of the scientific panel on contaminants in the food chain on a request from the commission related to deoxynivalenol (DON) as undesirable substance in animal feed
    • EFSA Available at:
    • EFSA Opinion of the scientific panel on contaminants in the food chain on a request from the commission related to deoxynivalenol (DON) as undesirable substance in animal feed. The EFSA Journal 2004, 73:1-41. Available at:. http://www.efsa.eu.int/.
    • (2004) The EFSA Journal , vol.73 , pp. 1-41
  • 10
    • 0025354406 scopus 로고
    • Laboratory models of sepsis and septic shock
    • Fink M.P., Heard S.O. Laboratory models of sepsis and septic shock. Journal of Surgical Research 1990, 49:186-196.
    • (1990) Journal of Surgical Research , vol.49 , pp. 186-196
    • Fink, M.P.1    Heard, S.O.2
  • 12
    • 33645872701 scopus 로고    scopus 로고
    • Bioavailability of the Fusarium toxin deoxynivalenol (DON) from naturally contaminated wheat for the pig
    • Goyarts T., Dänicke S. Bioavailability of the Fusarium toxin deoxynivalenol (DON) from naturally contaminated wheat for the pig. Toxicology Letters 2006, 163:171-182.
    • (2006) Toxicology Letters , vol.163 , pp. 171-182
    • Goyarts, T.1    Dänicke, S.2
  • 13
    • 33749582285 scopus 로고    scopus 로고
    • Effects of the Fusarium toxin deoxynivalenol from naturally contaminated wheat given subchronically or as one single dose on the in vivo protein synthesis of peripheral blood lymphocytes and plasma proteins in the pig
    • Goyarts T., Grove N., Dänicke S. Effects of the Fusarium toxin deoxynivalenol from naturally contaminated wheat given subchronically or as one single dose on the in vivo protein synthesis of peripheral blood lymphocytes and plasma proteins in the pig. Food and Chemical Toxicology 2006, 44:1953-1965.
    • (2006) Food and Chemical Toxicology , vol.44 , pp. 1953-1965
    • Goyarts, T.1    Grove, N.2    Dänicke, S.3
  • 14
    • 0027729864 scopus 로고
    • Relationship between tumor necrosis factor-alpha and neutrophils in endotoxin-induced liver injury
    • Hewett J.A., Jean P.A., Kunkel S.L., Roth R.A. Relationship between tumor necrosis factor-alpha and neutrophils in endotoxin-induced liver injury. American Journal of Physiology 1993, 265:G1011-G1015.
    • (1993) American Journal of Physiology , vol.265
    • Hewett, J.A.1    Jean, P.A.2    Kunkel, S.L.3    Roth, R.A.4
  • 15
    • 0027751698 scopus 로고
    • Hepatic and extrahepatic pathobiology of bacterial lipopolysaccharides
    • Hewett J.A., Roth R.A. Hepatic and extrahepatic pathobiology of bacterial lipopolysaccharides. Pharmacological Reviews 1993, 45:381-411.
    • (1993) Pharmacological Reviews , vol.45 , pp. 381-411
    • Hewett, J.A.1    Roth, R.A.2
  • 16
    • 0036534738 scopus 로고    scopus 로고
    • Endotoxin potentiation of trichothecene-induced lymphocyte apoptosis is mediated by up-regulation of glucocorticoids
    • Islam Z., Moon Y.S., Zhou H.R., King L.E., Fraker P.J., Pestka J.J. Endotoxin potentiation of trichothecene-induced lymphocyte apoptosis is mediated by up-regulation of glucocorticoids. Toxicology and Applied Pharmacology 2002, 180:43-55.
    • (2002) Toxicology and Applied Pharmacology , vol.180 , pp. 43-55
    • Islam, Z.1    Moon, Y.S.2    Zhou, H.R.3    King, L.E.4    Fraker, P.J.5    Pestka, J.J.6
  • 17
    • 0038155518 scopus 로고    scopus 로고
    • Role of IL-1(beta) in endotoxin potentiation of deoxynivalenol-induced corticosterone response and leukocyte apoptosis in mice
    • Islam Z., Pestka J.J. Role of IL-1(beta) in endotoxin potentiation of deoxynivalenol-induced corticosterone response and leukocyte apoptosis in mice. Toxicological Sciences 2003, 74:93-102.
    • (2003) Toxicological Sciences , vol.74 , pp. 93-102
    • Islam, Z.1    Pestka, J.J.2
  • 18
    • 31444448616 scopus 로고    scopus 로고
    • LPS priming potentiates and prolongs proinflammatory cytokine response to the trichothecene deoxynivalenol in the mouse
    • Islam Z., Pestka J.J. LPS priming potentiates and prolongs proinflammatory cytokine response to the trichothecene deoxynivalenol in the mouse. Toxicology and Applied Pharmacology 2006, 211:53-63.
    • (2006) Toxicology and Applied Pharmacology , vol.211 , pp. 53-63
    • Islam, Z.1    Pestka, J.J.2
  • 22
    • 0342723791 scopus 로고    scopus 로고
    • Nitric oxide in the pathogenesis of vascular disease
    • Li H., Förstermann U. Nitric oxide in the pathogenesis of vascular disease. Journal of Pathology 2000, 190:244-254.
    • (2000) Journal of Pathology , vol.190 , pp. 244-254
    • Li, H.1    Förstermann, U.2
  • 23
    • 0032044405 scopus 로고    scopus 로고
    • Statistical analysis of repeated measures data using SAS procedures
    • Littell R.C., Henry P.R., Ammerman C.B. Statistical analysis of repeated measures data using SAS procedures. Journal of Animal Science 1998, 76:1216-1231.
    • (1998) Journal of Animal Science , vol.76 , pp. 1216-1231
    • Littell, R.C.1    Henry, P.R.2    Ammerman, C.B.3
  • 25
    • 0037388879 scopus 로고    scopus 로고
    • Inflammatory mediator production in swine following endotoxin challenge with or without co-administration of dexamethasone
    • Myers M.J., Farrell D.E., Palmer D.C., Post L.O. Inflammatory mediator production in swine following endotoxin challenge with or without co-administration of dexamethasone. International Immunopharmacology 2003, 3:571-579.
    • (2003) International Immunopharmacology , vol.3 , pp. 571-579
    • Myers, M.J.1    Farrell, D.E.2    Palmer, D.C.3    Post, L.O.4
  • 26
    • 4444268646 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox
    • Pestka J.J., Zhou H.R., Moon Y., Chung Y.J. Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox. Toxicology Letters 2004, 153:61-73.
    • (2004) Toxicology Letters , vol.153 , pp. 61-73
    • Pestka, J.J.1    Zhou, H.R.2    Moon, Y.3    Chung, Y.J.4
  • 30
    • 11344279695 scopus 로고    scopus 로고
    • Bench-to-bedside review: sepsis is a disease of the microcirculation
    • Spronk P.E., Zandstra D.F., Ince C. Bench-to-bedside review: sepsis is a disease of the microcirculation. Critical Care 2004, 8:462-468.
    • (2004) Critical Care , vol.8 , pp. 462-468
    • Spronk, P.E.1    Zandstra, D.F.2    Ince, C.3
  • 32
    • 33846468553 scopus 로고    scopus 로고
    • The Commission of the European Communities Commission recommendation of 17 August 2006 on the presence of deoxynivalenol, zearalenone, ochratotin A, T-2 and HT-2 and fumonisins in products intended for animal feeding
    • The Commission of the European Communities Commission recommendation of 17 August 2006 on the presence of deoxynivalenol, zearalenone, ochratotin A, T-2 and HT-2 and fumonisins in products intended for animal feeding. Official Journal of the European Union L 2006, 229:7-9.
    • (2006) Official Journal of the European Union L , vol.229 , pp. 7-9
  • 33
    • 0027333425 scopus 로고
    • Tumor necrosis factor, other cytokines and disease
    • Tracey K.J., Cerami A. Tumor necrosis factor, other cytokines and disease. Annual Review of Cell Biology 1993, 9:317-343.
    • (1993) Annual Review of Cell Biology , vol.9 , pp. 317-343
    • Tracey, K.J.1    Cerami, A.2
  • 34
    • 0033952517 scopus 로고    scopus 로고
    • Lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol) synergistically induce apoptosis in murine lymphoid organs
    • Zhou H.R., Harkema J.R., Hotchkiss J.A., Yan D., Roth R.A., Pestka J.J. Lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol) synergistically induce apoptosis in murine lymphoid organs. Toxicological Sciences 2000, 53:253-263.
    • (2000) Toxicological Sciences , vol.53 , pp. 253-263
    • Zhou, H.R.1    Harkema, J.R.2    Hotchkiss, J.A.3    Yan, D.4    Roth, R.A.5    Pestka, J.J.6
  • 35
    • 0033612199 scopus 로고    scopus 로고
    • Amplified proinflammatory cytokine expression and toxicity in mice coexposed to lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol)
    • Zhou H.R., Harkema J.R., Yan D., Pestka J.J. Amplified proinflammatory cytokine expression and toxicity in mice coexposed to lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol). Journal of Toxicology and Environmental Health Part A 1999, 57:115-136.
    • (1999) Journal of Toxicology and Environmental Health Part A , vol.57 , pp. 115-136
    • Zhou, H.R.1    Harkema, J.R.2    Yan, D.3    Pestka, J.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.