Blocking TNF-α enhances Pseudomonas aeruginosa-induced mortality in burn mice through induction of IL-1β

Cytokine

Volumn 63, Issue 1, 2013, Pages 58-66

  Tsay, Tzyy Bin ^a   Yang, Ming Chieh ^b   Chen, Pei Hsuan ^b   Lai, Kuan Hung ^a   Huang, Hung Tu ^c   Hsu, Ching Mei ^d   Chen, Lee Wei ^b,e  

^a ZUOYING ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^b KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Burn; IL 1 ; NF B; Pseudomonas; Tumor necrosis factor

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COUNT; BURN; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; ENZYME ACTIVITY; INTRACELLULAR SIGNALING; LUNG INJURY; LUNG PERMEABILITY; MALE; MEMBRANE PERMEABILITY; MICROANGIOPATHY; MORTALITY; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PSEUDOMONAS INFECTION; PULMONARY MICROVASCULAR DYSFUNCTION; SURVIVAL RATE; THERMAL INJURY;

ANIMALS; BURNS; COLONY COUNT, MICROBIAL; DNA; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; LUNG; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; PEROXIDASE; PROTEIN BINDING; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RECEPTORS, INTERLEUKIN-1; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; SIGNAL TRANSDUCTION; TEMPERATURE; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; BACTERIA (MICROORGANISMS); MUS; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 84878951042     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2013.04.002     Document Type: Article

References (21)

1. Russell J.A. Management of sepsis. New Engl J Med 2006, 355:1699-1713.
2. Taneja N., Emmanuel R., Chari P.S., Sharma M. A prospective study of hospital-acquired infections in burn patients at a tertiary care referral centre in North India. Burns 2004, 30:665-669.
3. Li X., Xiang J., Liao Z. Statistical analysis of 4547 burn patients and the mortality in different periods. Chung Hua Cheng Hsing Shao Shang Wai Ko Tsa Chih. 1995, 11:335-338.
4. Lorente J.A., Marshall J.C. Neutralization of tumor necrosis factor in preclinical models of sepsis. Shock 2005, 24(Suppl 1):107-119.
5. Fisher C.J., Agosti J.M., Opal S.M., Lowry S.F., Balk R.A., Sadoff J.C., et al. Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The soluble TNF receptor sepsis study group. New Engl J Med 1996, 334:1697-1702.
6. Greten F.R., Arkan M.C., Bollrath J., Hsu L.C., Goode J., Miething C., et al. NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell 2007, 130:918-931.
7. Zhuang J., Xu J., Zhang C., Xu F. IL-1beta acutely increases pulmonary SP and permeability without associated changes in airway resistance and ventilation in anesthetized rats. Respirat Physiol Neurobiol 2011, 175:12-19.
8. Walker H.L., Mason A.D. A standard animal burn. J Trauma 1968, 8:1049-1051.
9. Brusselaers N, Monstrey S, Snoeij T, Vandijck D, Lizy C, Hoste E, et al. Morbidity and mortality of bloodstream infections in patients with severe burn injury. Am J Crit Care. vol. 19, p. e81-7.
10. Magnotti L.J., Upperman J.S., Xu D.Z., Lu Q., Deitch E.A. Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock. Ann Surg 1998, 228:518-527.
11. Patterson C.E., Rhoades R.A., Garcia J.G. Evans blue dye as a marker of albumin clearance in cultured endothelial monolayer and isolated lung [see comments]. J Appl Physiol 1992, 72:865-873.
12. Li N., Karin M. Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms. Proc Natl Acad Sci USA 1998, 95:13012-13017.
13. Liu Z.G. Molecular mechanism of TNF signaling and beyond. Cell Res 2005, 15:24-27.
14. Gosselin D., DeSanctis J., Boule M., Skamene E., Matouk C., Radzioch D. Role of tumor necrosis factor alpha in innate resistance to mouse pulmonary infection with Pseudomonas aeruginosa. Infect Immunol 1995, 63:3272-3278.
15. Mortelliti M.P., Manning H.L. Acute respiratory distress syndrome. Am Fam Physic 2002, 65:1823-1830.
16. Tsay T.B., Yang M.C., Chen P.H., Lin C.T., Hsu C.M., Chen L.W. TNF-alpha decreases infection-induced lung injury in burn through negative regulation of TLR4/iNOS. J Surg Res 2013, 179:106-114.
17. Chen L.W., Egan L., Li Z.W., Greten F.R., Kagnoff M.F., Karin M. The two faces of IKK and NF-kappaB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion. Nat Med 2003, 9:575-581.
18. Pascual V., Allantaz F., Arce E., Punaro M., Banchereau J. Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade. J Exp Med 2005, 201:1479-1486.
19. Farley K.S., Wang L., Mehta S. Septic pulmonary microvascular endothelial cell injury: role of alveolar macrophage NADPH oxidase. Am J Physiol Lung Cell Mol Physiol 2009, 296:L480-L488.
20. Al-Sadi R, Ye D, Said HM, Ma TY. IL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-kappaB pathway. Am J Pathol vol. 177, p. 2310-22.
21. Chen L.W., Chang W.J., Wang J.S., Hsu C.M. Thermal injury-induced peroxynitrite production and pulmonary inducible nitric oxide synthase expression depend on JNK/AP-1 signaling. Crit Care Med 2006, 34:142-150.