Morbidity and mortality of bloodstream infections in patients with severe burn injury

American Journal of Critical Care

Volumn 19, Issue 6, 2010, Pages

  Brusselaers, Nele ^a,b   Monstrey, Stan ^a,b   Snoeij, Thomas ^b   Vandijck, Dominique ^a,b   Lizy, Christelle ^b   Hoste, Eric ^a,b   Lauwaert, Stefaan ^a   Colpaert, Kirsten ^a,b   Vandekerckhove, Linos ^a,b   Vogelaers, Dirk ^a,b,c   Blot, Stijn ^a,b,c  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c UNIVERSITY COLLEGE GHENT   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BACTEREMIA; BELGIUM; BURN; CANDIDIASIS; COHORT ANALYSIS; ECONOMICS; FEMALE; GRAM NEGATIVE INFECTION; GRAM POSITIVE INFECTION; HEALTH CARE COST; HUMAN; INJURY SCALE; LENGTH OF STAY; MALE; MICROBIOLOGY; MIDDLE AGED; MORTALITY; PATHOPHYSIOLOGY; RETROSPECTIVE STUDY;

ADULT; AGED; BACTEREMIA; BELGIUM; BURNS; CANDIDIASIS; COHORT STUDIES; FEMALE; GRAM-NEGATIVE BACTERIAL INFECTIONS; GRAM-POSITIVE BACTERIAL INFECTIONS; HEALTH CARE COSTS; HUMANS; LENGTH OF STAY; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TRAUMA SEVERITY INDICES; YOUNG ADULT;

EID: 78249288766     PISSN: 10623264     EISSN: None     Source Type: Journal    
DOI: 10.4037/ajcc2010341     Document Type: Article

References (45)

1. Brusselaers N, Hoste EA, Monstrey S, et al. Outcome and changes over time in survival following severe burns from 1985 to 2004. Intensive Care Med. 2005;31(12):1648-1653.
2. Bang RL, Gang RK, Sanyal SC, Mokaddas E, Ebrahim MK. Burn septicaemia: an analysis of 79 patients. Burns. 1998; 24(4):354-361.
3. Bang RL, Sharma PN, Sanyal SC, Al Najjadah I. Septicaemia after burn injury: a comparative study. Burns. 2002;28(8): 746-751.
4. Barret J P, Herndon DN. Effects of burn wound excision on bacterial colonization and invasion. Plast Reconstr Surg. 2003;111(2):744-750.
5. Santucci SG, Gobara S, Santos CR, Fontana C, Levin AS. Infections in a burn intensive care unit: experience of seven years. J Hosp Infect. 2003;53(1):6-13.
6. Lawrence JC. Burn bacteriology during the last 50 years. Burns. 1992;18(suppl 2):S23-S29.
7. Brusselaers N, Lafaire C, Ortiz S, Jacquemin D, Monstrey S. The consensus of the surgical treatment of burn injuries in Belgium. Acta Chir Belg. 2008;108(6):645-650.
8. Pruitt BA Jr, McManus AT, Kim SH, Goodwin CW. Burn wound infections: current status. World J Surg. 1998; 22(2):135-145.
9. Bang RL, Sharma PN, Sanyal SC, Bang S, Ebrahim MK. Burn septicaemia in kuwait: associated demographic and clinical factors. Med Princ Pract. 2004;13(3):136-141.
10. Bang RL, Sharma PN, Gang RK, Ghoneim IE, Ebrahim MK. Burn mortality during 1982 to 1997 in kuwait. Eur J Epidemiol. 2000;16(8):731-739.
11. Tsai WP, Chen CL, Ko WC, Pan SC. Stenotrophomonas maltophilia bacteremia in burn patients. Burns. 2006;32(2): 155-158.
12. Ressner RA, Murray CK, Griffith ME, Rasnake MS, Hospenthal DR, Wolf SE. Outcomes of bacteremia in burn patients involved in combat operations overseas. J Am Coll Surg. 2008; 206(3):439-444.
13. Blot S, Depuydt P, Vandewoude K, De Bacquer D. Measuring the impact of multidrug resistance in nosocomial infection. Curr Opin Infect Dis. 2007;20(4):391-396.
14. Wisplinghoff H, Perbix W, Seifert H. Risk factors for nosocomial bloodstream infections due to Acinetobacter baumannii: a case-control study of adult burn patients. Clin Infect Dis. 1999;28(1):59-66.
15. Vinsonneau C, Benyamina M, Baixench M T, et al. Effects of candidaemia on outcome of burns. Burns. 2009;35(4):561-564.
16. Hoste EA, Blot SI, Lameire NH, Vanholder RC, De Bacquer D, Colardyn FA. Effect of nosocomial bloodstream infection on the outcome of critically ill patients with acute renal failure treated with renal replacement therapy. J Am Soc Nephrol. 2004;15(2):454-462.
17. Blot S, De Bacquer D, Hoste E, et al. Influence of matching for exposure time on estimates of attributable mortality caused by nosocomial bacteremia in critically ill patients. Infect Control Hosp Epidemiol. 2005;26(4):352-356.
18. Vandewoude KH, Blot SI, Benoit D, Colardyn F, Vogelaers D. Invasive aspergillosis in critically ill patients: attributable mortality and excesses in length of ICU stay and ventilator dependence. J Hosp Infect. 2004;56(4):269-276.
19. Falagas ME, Apostolou KE, Pappas VD. Attributable mortality of candidemia: a systematic review of matched cohort and case-control studies. Eur J Clin Microbiol Infect Dis. 2006; 25(7):419-425.
20. Costanza MC. Matching. Prev Med. 1995;24(5):425-433.
21. Grimes DA, Schulz KF. Cohort studies: marching towards outcomes. Lancet. 2002;359(9303):341-345.
22. Blot S, Brusselaers N, Monstrey S, et al; Belgian Outcome in Burn Injury Study Group. Development and validation of a model for prediction of mortality in patients with acute burn injury. Br J Surg. 2009;96(1):111-117.
23. Brusselaers N, Juhász I, Erdei I, Monstrey S, Blot S. Evaluation of mortality following severe burns injury in Hungary: external validation of a prediction model developed on Belgian burn data. Burns. 2009;35(7):1009-1014.
24. Blot SI, Depuydt P, Annemans L, et al. Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections. Clin Infect Dis. 2005;41(11): 1591-1598.
25. Blot SI, Vandewoude KH, Colardyn FA. Clinical impact of nosocomial Klebsiella bacteremia in critically ill patients. Eur J Clin Microbiol Infect Dis. 2002;21(6):471-473.
26. Depuydt P, Benoit D, Vogelaers D, et al. Outcome in bacteremia associated with nosocomial pneumonia and the impact of pathogen prediction by tracheal surveillance cultures. Intensive Care Med. 2006;32(11):1773-1781.
27. Blot S, Janssens R, Claeys G, et al. Effect of fluconazole consumption on long-term trends in candidal ecology. J Antimicrob Chemother. 2006;58(2):474-477.
28. Holley A, Dulhunty J, Blot S, et al. Temporal trends, risk factors and outcomes in albicans and non-albicans candi-daemia: an international epidemiological study in four multidisciplinary intensive care units. Int J Antimicrob Agents. 2009;33(6):554.e1-554.e7.
29. Bloemsma GC, Dokter J, Boxma H, Oen IM. Mortality and causes of death in a burn centre. Burns. 2008;34(8):1103-1107.
30. McGwin G Jr, George RL, Cross JM, Rue LW. Improving the ability to predict mortality among burn patients. Burns. 2008(34):320-327.
31. Saffle JR, Davis B, Williams P. Recent outcomes in the treatment of burn injury in the United States: a report from the American Burn Association Patient Registry. J Burn Care Rehabil. 1995;16(3 pt 1):219-232.
32. Blot S, Vandewoude K, Hoste E, et al. Absence of excess mortality in critically ill patients with nosocomial Escherichia coli bacteremia. Infect Control Hosp Epidemiol. 2003;24(12): 912-915.
33. Blot SI, Vandewoude KH, Colardyn FA. Evaluation of outcome in critically ill patients with nosocomial enterobacter bacteremia: results of a matched cohort study. Chest. 2003; 123(4):1208-1213.
34. Rello J, Ochagavia A, Sabanes E, et al. Evaluation of outcome of intravenous catheter-related infections in critically ill patients. Am J Respir Crit Care Med. 2000;162(3 Pt 1): 1027-1030.
35. Soufir L, Timsit J F, Mahe C, Carlet J, Regnier B, Chevret S. Attributable morbidity and mortality of catheter-related septicemia in critically ill patients: a matched, risk-adjusted, cohort study. Infect Control Hosp Epidemiol. 1999;20(6):396-401.
36. Garrouste-Orgeas M, Timsit J F, Tafflet M, et al; OUTCOMEREA Study Group. Excess risk of death from intensive care unit-acquired nosocomial bloodstream infections: a reappraisal [published correction appears in Clin Infect Dis. 2006;42(12):1818] Clin Infect Dis. 2006;42(8):1118-1126.
37. Falagas ME, Kopterides P, Siempos II. Attributable mortality of Acinetobacter baumannii infection among critically ill patients. Clin Infect Dis. 2006;43(3):389.
38. Blot S, Cankurtaran M, Petrovic M, et al. Epidemiology and outcome of nosocomial bloodstream infection in elderly critically ill patients: a comparison between middle-aged, old, and very old patients. Crit Care Med. 2009;37(5):1634-1641.
39. Kim PW, Perl TM, Keelaghan E F, et al. Risk of mortality with a bloodstream infection is higher in the less severely ill at admission. Am J Respir Crit Care Med. 2005;171(6):616-620.
40. Herruzo R, Banegas JR, Cruz JJ, Garcia-Torres V, Fernandez-Aceñero MJ. The etiology of bacteremia or pneumonia as a prognostic factor for death in burn patients, after a 10-day in intensive care unit. J Burn Care Res. 2008. DOI: 10.1097/BCR.obo13e3181711115.
41. Blot S, Vandewoude K. Early detection of systemic infections. Acta Clin Belg. 2004;59(1):20-23.
42. Kollef M. Appropriate empirical antibacterial therapy for nosocomial infections: getting it right the first time. Drugs. 2003;63(20):2157-2168.
43. Blot S. Limiting the attributable mortality of nosocomial infection and multidrug resistance in intensive care units. Clin Microbiol Infect. 2008;14(1):5-13.
44. Myny D, Depuydt P, Colardyn F, Blot S. Ventilator-associated pneumonia in a tertiary care ICU: analysis of risk factors for acquisition and mortality. Acta Clin Belg. 2005;60(3):114-121.
45. Ryan CM, Schoenfeld DA, Thorpe WP, Sheridan RL, Cassem EH, Tompkins RG. Objective estimates of the probability of death from burn injuries. N Engl J Med. 1998;338(6):362-366.