Investigation of NADH binding, hydride transfer, and NAD+ dissociation during NADH oxidation by mitochondrial complex i using modified nicotinamide nucleotides

Biochemistry

Volumn 52, Issue 23, 2013, Pages 4048-4055

  Birrell, James A ^a   Hirst, Judy ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FLAVIN MONONUCLEOTIDES; KINETIC ISOTOPE EFFECTS; MITOCHONDRIAL COMPLEX; MITOCHONDRIAL MATRIX; PROTON-MOTIVE FORCES; REACTIVE OXYGEN SPECIES; SUPEROXIDE PRODUCTION; TRANSITION STATE ENERGIES;

AMIDES; DISSOCIATION; HYDRIDES; ISOTOPES; NUCLEOTIDES; OXIDATION; OXYGEN;

BINDING ENERGY;

ADENOSINE; NICOTINAMIDE NUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ANIMAL CELL; ARTICLE; BINDING KINETICS; CHEMICAL REACTION; CONTROLLED STUDY; DISSOCIATION CONSTANT; ELECTRON TRANSPORT; ENZYME SUBSTRATE; INHIBITION KINETICS; MITOCHONDRION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT;

ADENOSINE; ADENOSINE DIPHOSPHATE; ADENOSINE DIPHOSPHATE RIBOSE; ADENOSINE MONOPHOSPHATE; ANIMALS; BINDING, COMPETITIVE; CATTLE; COENZYMES; ELECTRON TRANSPORT COMPLEX I; FLAVINS; HYDROGEN; KINETICS; MITOCHONDRIA, HEART; MODELS, MOLECULAR; NAD; NICOTINAMIDE MONONUCLEOTIDE; OXIDATION-REDUCTION; PROTEIN BINDING;

EID: 84878930284     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3016873     Document Type: Article

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