Methylenebis(sulfonamide) linked nicotinamide adenine dinucleotide analogue as an inosine monophosphate dehydrogenase inhibitor

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 11, 2007, Pages 3152-3155

  Chen, Liqiang ^a   Gao, Guangyao ^a   Bonnac, Laurent ^a   Wilson, Daniel J ^a   Bennett, Eric M ^a   Jayaram, Hiremagalur N ^b   Pankiewicz, Krzysztof W ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

IMPDH; Inosine monophosphate dehydrogenase; Methylenebis(sulfonamide); NAD analogue; Pyrophosphate mimics

Indexed keywords

2,4 DIMETHOXYBENZYL; INOSINATE DEHYDROGENASE INHIBITOR; METHYLENEBIS(SULFONAMIDE); NICOTINAMIDE ADENINE DINUCLEOTIDE; SULFONAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; MITSUNOBU REACTION; SYNTHESIS;

ENZYME INHIBITORS; HUMANS; IMP DEHYDROGENASE; MOLECULAR STRUCTURE; NAD; SULFONAMIDES;

EID: 34247859240     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.03.035     Document Type: Article

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