Structural flexibility of CaV1.2 and CaV2.2 I-II proximal linker fragments in solution

Biophysical Journal

Volumn 104, Issue 11, 2013, Pages 2392-2400

  Almagor, Lior ^a   Avinery, Ram ^a   Hirsch, Joel A ^a   Beck, Roy ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL N TYPE; GUANYLATE KINASE; L TYPE CALCIUM CHANNEL ALPHA(1C); L-TYPE CALCIUM CHANNEL ALPHA(1C); SOLUTION AND SOLUBILITY;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; RABBIT; SOLUTION AND SOLUBILITY;

ANIMALS; CALCIUM CHANNELS, L-TYPE; CALCIUM CHANNELS, N-TYPE; GUANYLATE KINASE; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RABBITS; SOLUTIONS;

EID: 84878888255     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2013.04.034     Document Type: Article

References (32)

1. S.W. Jones Overview of voltage-dependent calcium channels J. Bioenerg. Biomembr. 30 1998 299 312
2. Z. Buraei, and J.A. Yang The β subunit of voltage-gated Ca2+ channels Physiol. Rev. 90 2010 1461 1506
3. Y.H. Chen, and M.H. Li J. Yang Structural basis of the α1-β subunit interaction of voltage-gated Ca2+ channels Nature 429 2004 675 680
4. Y. Opatowsky, and C.C. Chen J.A. Hirsch Structural analysis of the voltage-dependent calcium channel β subunit functional core and its complex with the α1 interaction domain Neuron 42 2004 387 399
5. F. Van Petegem, and K.A. Clark D.L. Minor Jr. Structure of a complex between a voltage-gated calcium channel β-subunit and an α-subunit domain Nature 429 2004 671 675
6. 2+ channels J. Neurosci. 28 2008 14176 14188
7. 2+ channels FEBS Lett. 579 2005 3907 3912
8. I. Vitko, and A. Shcheglovitov E. Perez-Reyes Orientation of the calcium channel β relative to the α(1)2.2 subunit is critical for its regulation of channel activity PLoS ONE 3 2008 e3560
9. F. Findeisen, and D.L. Minor Jr. Disruption of the IS6-AID linker affects voltage-gated calcium channel inactivation and facilitation J. Gen. Physiol. 133 2009 327 343
10. 2+ channel intracellular linker: a structure-function analysis J. Neurosci. 32 2012 7602 7613
11. L. Almagor, and O. Chomsky-Hecht J.A. Hirsch Ca(V)1.2 I-II linker structure and Timothy syndrome Channels (Austin) 6 2012 468 472
12. Y.L. Li, and R. Beck M. Divinagracia Scatterless hybrid metal-single-crystal slit for small-angle X-ray scattering and high-resolution X-ray diffraction J. Appl. Cryst. 41 2008 1134 1139
13. J. Gabadinho, and A. Beteva S.M. McSweeney MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments J. Synchrotron Radiat. 17 2010 700 707
14. P.V. Konarev, and V.V. Volkov D.I. Svergun PRIMUS: a Windows PC-based system for small-angle scattering data analysis J. Appl. Cryst. 36 2003 1277 1282
15. D. Svergun Determination of the regularization parameter in indirect-transform methods using perceptual criteria J. Appl. Cryst. 25 1992 495 503
16. M.V. Petoukhov, and P.V. Konarev D.I. Svergun ATSAS 2.1 - towards automated and web-supported small-angle scattering data analysis J. Appl. Cryst. 40 2007 s223 s228
17. D.I. Svergun, and M.H.J. Koch Small-angle scattering studies of biological macromolecules in solution Rep. Prog. Phys. 66 2003 1735 1782
18. A. Guinier La diffraction des rayons X aux tres petits angles: application a l'etude de phenomenes ultramicroscopiques Ann. Phys. (Paris) 12 1939 161 237
19. P. Bernadó, and E. Mylonas D.I. Svergun Structural characterization of flexible proteins using small-angle X-ray scattering J. Am. Chem. Soc. 129 2007 5656 5664
20. D. Svergun, C. Barberato, and M.H.J. Koch CRYSOL - a program to evaluate x-ray solution scattering of biological macromolecules from atomic coordinates J. Appl. Cryst. 28 1995 768 773
21. A. Roy, A. Kucukural, and Y. Zhang I-TASSER: a unified platform for automated protein structure and function prediction Nat. Protoc. 5 2010 725 738
22. S. Doniach Changes in biomolecular conformation seen by small angle X-ray scattering Chem. Rev. 101 2001 1763 1778
23. R. Linding, and L.J. Jensen R.B. Russell Protein disorder prediction: implications for structural proteomics Structure 11 2003 1453 1459
24. R. Linding, and R.B. Russell T.J. Gibson GlobPlot: exploring protein sequences for globularity and disorder Nucleic Acids Res. 31 2003 3701 3708
25. K.T. O'Neil, and W.F. DeGrado A thermodynamic scale for the helix-forming tendencies of the commonly occurring amino acids Science 250 1990 646 651
26. T.P. Creamer, and G.D. Rose α-Helix-forming propensities in peptides and proteins Proteins 19 1994 85 97
27. B.J. Spink, and S. Sivaramakrishnan J.A. Spudich Long single α-helical tail domains bridge the gap between structure and function of myosin VI Nat. Struct. Mol. Biol. 15 2008 591 597
28. P.J. Knight, and K. Thirumurugan M. Peckham The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head J. Biol. Chem. 280 2005 34702 34708
29. M. Peckham, and P.J. Knight When a predicted coiled coil is really a single α-helix, in myosins and other proteins Soft Matter 5 2009 2493 2503
30. S. Sivaramakrishnan, and B.J. Spink J.A. Spudich Dynamic charge interactions create surprising rigidity in the ER/K α-helical protein motif Proc. Natl. Acad. Sci. USA 105 2008 13356 13361
31. D. Süveges, and Z. Gáspári L. Nyitray Charged single α-helix: a versatile protein structural motif Proteins 74 2009 905 916
32. I. Splawski, and K.W. Timothy M.T. Keating Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism Cell 119 2004 19 31