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Volumn 6, Issue 6, 2012, Pages 468-472

Cav1.2 I-II linker structure and Timothy syndrome

Author keywords

Timothy syndrome; Voltage dependent calcium channels; Voltage dependent inactivation; helix

Indexed keywords

CALCIUM CHANNEL; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT CALCIUM CHANNEL 1.2;

EID: 84871439392     PISSN: 19336950     EISSN: 19336969     Source Type: Journal    
DOI: 10.4161/chan.22078     Document Type: Article
Times cited : (8)

References (9)
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  • 2
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    • Splawski, I.1    Timothy, K.W.2    Sharpe, L.M.3    Decher, N.4    Kumar, P.5    Bloise, R.6
  • 4
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    • The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels
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    • Barrett CF, Tsien RW. The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels. Proc Natl Acad Sci U S A 2008; 105:2157-62; PMID:18250309; http://dx.doi.org/10.1073/pnas.0710501105.
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    • discussion 8086-8; PMID:15863612
    • Splawski I, Timothy KW, Decher N, Kumar P, Sachse FB, Beggs AH, et al. Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations. Proc Natl Acad Sci U S A 2005; 102:8089-96, discussion 8086-8; PMID:15863612; http://dx.doi.org/10.1073/pnas.0502506102.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 8089-8096
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  • 6
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    • Introduction into Ca(v)2.1 of the homologous mutation of Ca(v)1.2 causing the Timothy syndrome questions the role of V421 in the phenotypic definition of P-type Ca(2+) channel
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    • Cens T, Leyris JP, Charnet P. Introduction into Ca(v)2.1 of the homologous mutation of Ca(v)1.2 causing the Timothy syndrome questions the role of V421 in the phenotypic definition of P-type Ca(2+) channel. Pf lugers Arch 2008; 457:417-30; PMID:18536931; http://dx.doi.org/10.1007/s00424-008-0534-1.
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  • 7
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    • Yarotskyy V, Gao G, Peterson BZ, Elmslie KS. The Timothy syndrome mutation of cardiac CaV1.2 (L-type) channels: multiple altered gating mechanisms and pharmacological restoration of inactivation. J Physiol 2009; 587:551-65; PMID:19074970; http://dx.doi.org/10.1113/jphysiol.2008.161737.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.