Synthesis and biological evaluation of novel series of thieno[2,3-d] pyrimidine derivatives as anticancer and antimicrobial agents

Medicinal Chemistry Research

Volumn 22, Issue 7, 2013, Pages 3289-3308

  Habib, Nargues S ^a   Soliman, Raafat ^a   El Tombary, Alaa A ^a   El Hawash, Soad A ^a   Shaaban, Omaima G ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Anticancer; Antimicrobial; Synthesis; Thieno 2,3 d pyrimidine

Indexed keywords

2 (4 CHLOROPHENYLCARBAMOYLMETHYLTHIO) 5 METHYL 4 OXO 3 PHENYL 3,4 DIHYDROTHIENO[2,3 D]PYRIMIDINE 6 CARBOXAMIDE; 3 (2 HYDROXYETHYL) 5 METHYL 4 OXO 3,4 DIHYDROTHIENO [2,3 D]PYRIMIDINE 6 CARBOXAMIDE; 3 (3 BENZYL 4 PHENYLTHIAZOL 2(3H) YLIDENEAMINO) 2,5 DIMETHYL 4 OXO 3,4 DIHYDROTHIENO[2,3 D]PYRIMIDINE 6 CARBOXAMIDE; AMPICILLIN; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTINEOPLASTIC AGENT; CLOTRIMAZOLE; THIENO[2,3 D]PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BRAIN CANCER; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CANDIDA ALBICANS; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY CANCER; LC 50; LEUKEMIA; LUNG NON SMALL CELL CANCER; MELANOMA; MINIMUM INHIBITORY CONCENTRATION; OVARY CANCER; PROSTATE CANCER; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA;

EID: 84878855463     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0324-3     Document Type: Article

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