Synthesis of tetrahydrobenzothieno[2,3-d]pyrimidine and tetrahydrobenzothieno[3,2-e]-[1,2,4]triazolo[4,3-c]pyrimidine derivatives as potential antimicrobial agents

Scientia Pharmaceutica

Volumn 77, Issue 4, 2009, Pages 755-773

  Soliman, Raafat ^a   Habib, Nargues S ^a   El Tombary, Alaa A ^a   El Hawash, Soad A M ^a   Shaaban, Omaima G ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Antimicrobial activity; Pyrazole; Synthesis; Tetrahydrobenzothieno 2,3 d pyrimidine; Triazolotetrahydrobenzothienopyrimidine

Indexed keywords

3 (3 CHLOROPHENYL) 8,9,10,11 TETRAHYDRO[1]BENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE; 3 (4 NITROPHENYL) 8,9,10,11 TETRAHYDRO[1]BENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE; 4 (3 METHYL 5 PHENYL 1H PYRAZOL 1 YL) 5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDINE; 4 (4 BENZYLPIPERAZIN 1 YL) 5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDINE; 4 (4 BENZYLPIPERIDIN 1 YL) 5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDINE; 4 (MORPHOLIN 4 YL) 5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDINE; 4 (PIPERIDIN 1 YL) 5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDINE; 4 [2 (PYRIDIN 4 YLMETHYLIDENE)HYDRAZINO] 5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDINE; 4 [2 (THIOPHEN 3 YLMETHYLIDENE)HYDRAZINO] 5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDINE; 4 [2 [(1,3 DIPHENYL 1H PYRAZOL 5 YL)METHYLIDENE]HYDRAZINO] 5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDINE; 4 HYDRAZINO 5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDINE; ACETAMIDE DERIVATIVE; AMPICILLIN; ANTIINFECTIVE AGENT; CLOTRIMAZOLE; ETHYL 5 PHENYL 1 (5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDIN 4 YL) 1H PYRAZOL 3 CARBOXYLATE; N (4 CHLOROPHENYL) 2 (8,9,10,11 TETRAHYDRO[1]BENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDIN 3 YLSULFANYL)ACETAMIDE; N (4 METHYLPHENYL) 2 (8,9,10,11 TETRAHYDRO[1]BENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDIN 3 YLSULFANYL)ACETAMIDE; N PHENYL 2 (8,9,10,11 TETRAHYDRO[1]BENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDIN 3 YLSULFANYL)ACETAMIDE; PYRIMIDINE DERIVATIVE; TETRAHYDROBENZOTHIENO[2,3 D]PYRIMIDINE DERIVATIVE; TETRAHYDROBENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; BACTERIOSTASIS; CANDIDA ALBICANS; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG SYNTHESIS; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 74549201524     PISSN: 00368709     EISSN: 22180532     Source Type: Journal    
DOI: 10.3797/scipharm.0904-17     Document Type: Article

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