Aryl hydrocarbon receptor-mediated disruption of contact inhibition is associated with connexin43 downregulation and inhibition of gap junctional intercellular communication

Archives of Toxicology

Volumn 87, Issue 3, 2013, Pages 491-503

  Andrysík, Zdeněk ^a,c   Procházková, Jiřina ^a,b   Kabátková, Markéta ^a   Umannová, Lenka ^a,b   Šimečková, Pavlína ^b   Kohoutek, Jiří ^b   Kozubík, Alois ^a   MacHala, Miroslav ^b   Vondráček, Jan ^a,b  

^a INSTITUTE OF BIOPHYSICS   (Czech Republic)

^b VETERINARY RESEARCH INSTITUTE   (Czech Republic)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

Aryl hydrocarbon receptor; Connexin43; Contact inhibition; Gap junctions; Liver epithelial cells

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CONNEXIN 43; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROTEASOME; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CELL PROLIFERATION; CONTACT INHIBITION; CONTACT INHIBITION DISRUPTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME DEGRADATION; EPITHELIUM CELL; G1 PHASE CELL CYCLE CHECKPOINT; GAP JUNCTION; GENE SILENCING; GENETIC TRANSCRIPTION; LIVER CELL; LIVER LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; RAT; TUMOR GROWTH;

ANIMALS; BENZ(A)ANTHRACENES; CARCINOGENS; CELL COMMUNICATION; CELL LINE; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CONNEXIN 43; CONTACT INHIBITION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; EPITHELIAL CELLS; FLUORENES; GAP JUNCTIONS; GENE KNOCKDOWN TECHNIQUES; INDOLES; LIGANDS; LIVER; LIVER NEOPLASMS; PHLOROGLUCINOL; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RECEPTORS, ARYL HYDROCARBON; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TETRACHLORODIBENZODIOXIN; TIME FACTORS; TRANSFECTION;

EID: 84878836095     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0963-7     Document Type: Article

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