The advantages of microflow LC-MS/MS compared with conventional HPLC-MS/MS for the analysis of methotrexate from human plasma

Bioanalysis

Volumn 5, Issue 11, 2013, Pages 1387-1396

  Christianson, Chad C ^a   Johnson, Casey J L ^a   Needham, Shane R ^a  

^a Alturas Analytics Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHOTREXATE; SOLVENT;

ACCURACY; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; COST; DRUG DETERMINATION; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTERMETHOD COMPARISON; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROFLOW LIQUID CHROMATOGRAPHY; VALIDATION PROCESS;

ANTIMETABOLITES, ANTINEOPLASTIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EQUIPMENT DESIGN; HUMANS; LIMIT OF DETECTION; METHOTREXATE; TANDEM MASS SPECTROMETRY;

EID: 84878832740     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.13.73     Document Type: Article

References (33)

1. Lin Y, Schiavo S, Orjala J, Vouros P, Kautz R. Microscale LC-MS-NMR platform applied to the identification of active cyanobacterial metabolites. Anal. Chem. 80(21), 8045-8054 (2008
2. Ramanathan R, Zhong R, Blumenkrantz N, Chowdhury SK, Alton KB. Response normalized liquid chromatography nanospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom. 18(10), 1891-1899 (2007
3. Valaskovic G, Utley L, Lee J, Wu J. Ultra-low flow nanospray for the normalization of conventional liquid chromatography/mass spectrometry through equimolar response: Standard-free quantitative estimation of metabolite levels in drug discovery. Rapid Commun. Mass Spectrom. 20(7), 1087-1096 (2006
4. Wickremsinhe E, Singh G, Ackermann B, Gillespie T, Chaudhary A. A review of nanoelectrospray ionization applications for drug metabolism and pharmacokinetics. Curr. Drug Metab. 7(8), 913-928 (2006
5. Valaskovic G Kelleher N. Miniaturized formats for efficient mass spectrometry-based proteomics and therapeutic development. Curr. Top. Med. Chem. 2(1), 1-12, (2002
6. Juraschek R, Dulcks T, Karas M. Nanoelectrospray -more than just a minimized-flow-electrospray ionization source. J. Am. Soc. Mass Spectrom. 10(4), 300-308 (1999
7. Gang E, Annan M, Spooner N, Vouros P. Reduction of signal suppression effects in esi-ms using a nanosplitting device. Anal. Chem. 73(23), 5635-5644 (2001
8. Armenta S, Garrigues S, de la Guardia M. Green analytical chemistry. Trends Analyt. Chem. 27(6), 497-511 (2008
9. Chen H, Wang Y, Lin W. Analysis of ethylated thymidine adducts in human leukocyte DNA by stable isotope dilution nanoflow liquid chromatography- nanospray ionization tandem mass spectrometry. Anal. Chem. 84(5), 2521-2527 (2012
10. Zhang X, Hojlund K, Luo M, Meyer C, Geetha T, Yi Z. Novel tyrosine phosphorylation sites in rat skeletal muscle revealed by phosphopeptide enrichment and HPLC-ESI-MS/MS. J. Proteomics 75(13), 4017-4026 (2012
11. Gates P, Lopes N. Characterization of flavonoid aglycones by negative ion chip-based nanospray tandem mass spectrometry. Int. J. Anal. Chem. 2012, 259217 (2012
12. Eckert P, Roach P, Laskin A, Laskin J. Chemical characterization of crude petroleum using nanospray desorption electrospray ionization couple with high-resolution mass spectrometry. J. Chrom. B 1217(29), 4808-4814 (2010
13. Hoogland F, Boon J. Analytical mass spectrometry of poly(ethylene glycol) additives in artists' acrylic emulsion media, artists' paints, and microsamples from acrylic paintings using MALDI-MS and nanospray-ESI-MS. Int. J. Mass Spectrom. 284(1-3), 72-80 (2009
14. Horn P, Joshi U, Behrendt A, Chapman K, Verbeck G. On-stage liquid-phase lipid microextraction coupled to nanospray mass spectrometry for detailed, nano-scale lipid analysis. Rapid Commun. Mass Spectrom. 26(8), 957-962 (2012
15. Laskin J, Heath B, Roach P, Cazares L, Semmes O. Tissue imaging using nanospray desorption electrospray ionization mass spectrometry. Anal. Chem. 84(1), 141-148 (2012
16. Wilm M, Mann M, Electrospray and taylor-cone theory, dole's beam of macromolecules at last. Int. J. Mass Spectrom. Ion Process. 136(2-3), 167-180 (1994
17. Christianson C, Needham S. Hobbs S. Comparison of traditional HPLC-MS/MS sensitivity to the sensitivity of micro flow liquid chromatography-MS/MS. Proceedings of the American Society of Mass Spectrometry Conference. Denver, CO, USA, 5-9 June 2011
18. Sangster T, Oliver M. Challenges faced by the modern bioanalytical laboratory. Bioanalysis 4(19), 2329-2333 (2012
19. Wojcik R, Dada O, Sadilek M, Dovichi N. Simplified capillary electrophoresis nanospray sheath-flow interface for high efficiency and sensitive peptide analysis. Rapid Commun. Mass Spectrom. 24(17), 2554-2560 (2010
20. Gapeev A, Berton A, Fabris D. Current-controlled nanospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom. 20(7) 1334-1341 (2009
21. Michalski A, Damoc E, Lange O et al. Ultra high resolution linear ion trap orbitrap mass spectrometer (orbitrap elite) facilitates top down LC-MS/MS and versatile peptide fragmentation modes. Mol. Cell Proteomics 11(3), doi:10.1074/mcp.O111.013698 (2012
22. Love D, Stratton E, Stocum M. Best practices for companion diagnostics and therapeutic development: Translating between the stakeholders. Mol. Diagnost. Personal. Med. 29(6), 689-694 (2012
23. Christians U, Klepacki J, Shokati T, Klawitter J, Klawitter J. Mass spectrometry-based multiplexing for the analysis of biomarkers in drug development and clinical diagnostics -how much is too much?. Microchem. J. 105, 32-38 (2012
24. Heemskerk A, Busnel J, Schoenmaker B et al. Ultra-low flow electrospray ionization-mass spectrometry for improve ionization efficiency in phosphoproteomics. Anal. Chem. 84(10), 4552-4559 (2012
25. Kleiman M, Saqi Y, Bloch N, Aqur Z. Use of virtual patient populations for rescuing discontinued drug candidates and for reducing the number of patients in clinical trials. Altern. Lab. Anim. 37(Suppl. 1), 39-45 (2009
26. Spooner N, Rakesh L, Barfield M. Dried blood spots as a sample collection technique for the determination of pharmacokinetics in clinical studies: Considerations for the validation of a quantitative bioanalytical method. Anal. Chem. 81(4), 1557-1563 (2009
27. Lun V. Green management practices and firm performance: A case of container terminal operations. Environ. Supply Chain Manage. 55(6), 559-566 (2011
28. Khan Z, Tripathi R, Mishra B. Methotrexate: A detailed review on drug delivery and clinical aspects. Expert Opin. Drug Deliv. 9(2), 151-169 (2012
29. US Department of Health and Services, US FDA, Center for Drug Evaluation and Research. Guidance for Industry: Bioanalytical Method Validation. FDA, Rockville, MD, USA (2001
30. Viswanathan C, Bansal S, Booth B et al. Workshop/conference report-quantitative bioanalytical methods validation and implementation: Best practices for chromatographic and ligand binding assays. AAPS J. 9(1), E30-E42 (2007
31. Snyder LR, Kirkland JJ, Glajch JL. Practical HPLC Method Development (2nd Edition). John Wiley & Sons, Inc., NY, USA, 47-49 (1997
32. Christianson C, Laine D, Zimmer J et al. Development and validation of an HPLC-MS/MS method for the analysis of dexamethasone from pig synovial fluid using dried matrix spotting. Bioanalysis 2(11), 1829-1837 (2010
33. Schneider BB, Guo X, Fell LM, Covey TR. Stable gradient nanoflow LC-MS. J. Am. Soc. Mass Spectrom. 16(9), 1545-1551 (2005