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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 13, 2013, Pages 3942-3946

Discovery of N-(4′-(indol-2-yl)phenyl)sulfonamides as novel inhibitors of HCV replication

(16) Chen, Guangming a Ren, Hongyu a Turpoff, Anthony a Arefolov, Alexander a Wilde, Richard a Takasugi, James a Khan, Atiyya a Almstead, Neil a Gu, Zhengxian a Komatsu, Takashi a Freund, Connie a Breslin, Jamie a Colacino, Joseph a Hedrick, Jean a Weetall, Marla a Karp, Gary M a

a PTC THERAPEUTICS (United States)

Author keywords

HCV inhibitors; N (Indol 2 yl)phenyl sulfonamide; Replicon; Structure activity relationship

Indexed keywords

2 PHENYLINDOLE DERIVATIVE; SULFONAMIDE;

ARTICLE; CYTOTOXICITY; DRUG BIOAVAILABILITY; DRUG HALF LIFE; DRUG POTENCY; DRUG SYNTHESIS; GENOTYPE; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; LIVER MICROSOME; NONHUMAN; RAT; REPLICON; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; BIOLOGICAL AVAILABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; HEPACIVIRUS; HUMANS; INDOLES; MICROBIAL SENSITIVITY TESTS; MICROSOMES, LIVER; MOLECULAR STRUCTURE; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; VIRUS REPLICATION;

HEPATITIS C VIRUS; RATTUS;

EID: 84878826680 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.04.050 Document Type: Article

Times cited : (20)

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