Loss of Otx2 in the adult retina disrupts retinal pigment epithelium function, causing photoreceptor degeneration

Journal of Neuroscience

Volumn 33, Issue 24, 2013, Pages 9890-9904

  Housset, Michael ^a,b   Samuel, Alexander ^a,b   Ettaiche, Mohamed ^c   Bemelmans, Alexis ^d   Béby, Francis ^e   Billon, Nathalie ^a,b   Lamonerie, Thomas ^a,b  

^a CENTRE DE BIOCHIMIE   (France)

^b CNRS   (France)

^c INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^d INSTITUT DE RADIOBIOLOGIE CELLULAIRE ET MOLÉCULAIRE   (France)

^e HOP UNIV DES ENFANTS REINE FABIOLA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR OTX2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DARK ADAPTATION; ELECTRORETINOGRAPHY; GENE CONTROL; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MELANOGENESIS; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RETINA PIGMENT DEGENERATION;

AGE FACTORS; ANIMALS; ASTROCYTES; CHROMATIN IMMUNOPRECIPITATION; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; LENTIVIRUS; MALE; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OTX TRANSCRIPTION FACTORS; PHOTORECEPTOR CELLS; PROTEIN BINDING; RETINA; RETINAL DEGENERATION; RETINAL PIGMENT EPITHELIUM; RNA, MESSENGER;

EID: 84878826576     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1099-13.2013     Document Type: Article

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