-
1
-
-
0025763419
-
Max: A helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc
-
E.M. Blackwood, and R.N. Eisenman Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc Science 251 1991 1211 1217
-
(1991)
Science
, vol.251
, pp. 1211-1217
-
-
Blackwood, E.M.1
Eisenman, R.N.2
-
2
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature 455 2008 1061 1068
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
3
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
H.R. Christofk, M.G. Vander Heiden, M.H. Harris, A. Ramanathan, R.E. Gerszten, R. Wei, M.D. Fleming, S.L. Schreiber, and L.C. Cantley The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth Nature 452 2008 230 233
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
4
-
-
40749099894
-
Pyruvate kinase M2 is a phosphotyrosine-binding protein
-
H.R. Christofk, M.G. Vander Heiden, N. Wu, J.M. Asara, and L.C. Cantley Pyruvate kinase M2 is a phosphotyrosine-binding protein Nature 452 2008 181 186
-
(2008)
Nature
, vol.452
, pp. 181-186
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Wu, N.3
Asara, J.M.4
Cantley, L.C.5
-
5
-
-
76649102764
-
The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
-
C.V. Clower, D. Chatterjee, Z. Wang, L.C. Cantley, M.G. Vander Heiden, and A.R. Krainer The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism Proc. Natl. Acad. Sci. USA 107 2010 1894 1899
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 1894-1899
-
-
Clower, C.V.1
Chatterjee, D.2
Wang, Z.3
Cantley, L.C.4
Vander Heiden, M.G.5
Krainer, A.R.6
-
6
-
-
84867424108
-
Therapeutic targeting of Myc-reprogrammed cancer cell metabolism
-
C.V. Dang Therapeutic targeting of Myc-reprogrammed cancer cell metabolism Cold Spring Harb. Symp. Quant. Biol. 76 2011 369 374
-
(2011)
Cold Spring Harb. Symp. Quant. Biol.
, vol.76
, pp. 369-374
-
-
Dang, C.V.1
-
7
-
-
84859171807
-
MYC on the path to cancer
-
C.V. Dang MYC on the path to cancer Cell 149 2012 22 35
-
(2012)
Cell
, vol.149
, pp. 22-35
-
-
Dang, C.V.1
-
8
-
-
75149150660
-
HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
-
C.J. David, M. Chen, M. Assanah, P. Canoll, and J.L. Manley HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer Nature 463 2010 364 368
-
(2010)
Nature
, vol.463
, pp. 364-368
-
-
David, C.J.1
Chen, M.2
Assanah, M.3
Canoll, P.4
Manley, J.L.5
-
9
-
-
37449024702
-
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
-
R.J. DeBerardinis, J.J. Lum, G. Hatzivassiliou, and C.B. Thompson The biology of cancer: metabolic reprogramming fuels cell growth and proliferation Cell Metab. 7 2008 11 20
-
(2008)
Cell Metab.
, vol.7
, pp. 11-20
-
-
Deberardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
Thompson, C.B.4
-
10
-
-
79952501323
-
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
-
L.W. Finley, A. Carracedo, J. Lee, A. Souza, A. Egia, J. Zhang, J. Teruya-Feldstein, P.I. Moreira, S.M. Cardoso, and C.B. Clish SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization Cancer Cell 19 2011 416 428
-
(2011)
Cancer Cell
, vol.19
, pp. 416-428
-
-
Finley, L.W.1
Carracedo, A.2
Lee, J.3
Souza, A.4
Egia, A.5
Zhang, J.6
Teruya-Feldstein, J.7
Moreira, P.I.8
Cardoso, S.M.9
Clish, C.B.10
-
11
-
-
35949002429
-
Malignant astrocytic glioma: Genetics, biology, and paths to treatment
-
F.B. Furnari, T. Fenton, R.M. Bachoo, A. Mukasa, J.M. Stommel, A. Stegh, W.C. Hahn, K.L. Ligon, D.N. Louis, and C. Brennan Malignant astrocytic glioma: genetics, biology, and paths to treatment Genes Dev. 21 2007 2683 2710
-
(2007)
Genes Dev.
, vol.21
, pp. 2683-2710
-
-
Furnari, F.B.1
Fenton, T.2
Bachoo, R.M.3
Mukasa, A.4
Stommel, J.M.5
Stegh, A.6
Hahn, W.C.7
Ligon, K.L.8
Louis, D.N.9
Brennan, C.10
-
12
-
-
78249255491
-
FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis
-
B. Gan, C. Lim, G. Chu, S. Hua, Z. Ding, M. Collins, J. Hu, S. Jiang, E. Fletcher-Sananikone, and L. Zhuang FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis Cancer Cell 18 2010 472 484
-
(2010)
Cancer Cell
, vol.18
, pp. 472-484
-
-
Gan, B.1
Lim, C.2
Chu, G.3
Hua, S.4
Ding, Z.5
Collins, M.6
Hu, J.7
Jiang, S.8
Fletcher-Sananikone, E.9
Zhuang, L.10
-
13
-
-
69149097363
-
The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis
-
D. Guo, I.J. Hildebrandt, R.M. Prins, H. Soto, M.M. Mazzotta, J. Dang, J. Czernin, J.Y. Shyy, A.D. Watson, and M. Phelps The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis Proc. Natl. Acad. Sci. USA 106 2009 12932 12937
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12932-12937
-
-
Guo, D.1
Hildebrandt, I.J.2
Prins, R.M.3
Soto, H.4
Mazzotta, M.M.5
Dang, J.6
Czernin, J.7
Shyy, J.Y.8
Watson, A.D.9
Phelps, M.10
-
14
-
-
77649216053
-
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy
-
D. Guo, R.M. Prins, J. Dang, D. Kuga, A. Iwanami, H. Soto, K.Y. Lin, T.T. Huang, D. Akhavan, and M.B. Hock EGFR signaling through an Akt-SREBP-1- dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy Sci. Signal. 2 2009 ra82
-
(2009)
Sci. Signal.
, vol.2
, pp. 82
-
-
Guo, D.1
Prins, R.M.2
Dang, J.3
Kuga, D.4
Iwanami, A.5
Soto, H.6
Lin, K.Y.7
Huang, T.T.8
Akhavan, D.9
Hock, M.B.10
-
15
-
-
84861101004
-
An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway
-
D. Guo, F. Reinitz, M. Youssef, C. Hong, D. Nathanson, D. Akhavan, D. Kuga, A.N. Amzajerdi, H. Soto, and S. Zhu An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway Cancer Discov. 1 2011 442 456
-
(2011)
Cancer Discov.
, vol.1
, pp. 442-456
-
-
Guo, D.1
Reinitz, F.2
Youssef, M.3
Hong, C.4
Nathanson, D.5
Akhavan, D.6
Kuga, D.7
Amzajerdi, A.N.8
Soto, H.9
Zhu, S.10
-
16
-
-
0028011993
-
Differential expression of myc, max and RB1 genes in human gliomas and glioma cell lines
-
H.E. Hirvonen, R. Salonen, M.M. Sandberg, E. Vuorio, I. Västrik, E. Kotilainen, and H. Kalimo Differential expression of myc, max and RB1 genes in human gliomas and glioma cell lines Br. J. Cancer 69 1994 16 25
-
(1994)
Br. J. Cancer
, vol.69
, pp. 16-25
-
-
Hirvonen, H.E.1
Salonen, R.2
Sandberg, M.M.3
Vuorio, E.4
Västrik, I.5
Kotilainen, E.6
Kalimo, H.7
-
17
-
-
33748136848
-
The MAX-interacting transcription factor network
-
P.J. Hurlin, and J. Huang The MAX-interacting transcription factor network Semin. Cancer Biol. 16 2006 265 274
-
(2006)
Semin. Cancer Biol.
, vol.16
, pp. 265-274
-
-
Hurlin, P.J.1
Huang, J.2
-
18
-
-
79955398591
-
Otto Warburg's contributions to current concepts of cancer metabolism
-
W.H. Koppenol, P.L. Bounds, and C.V. Dang Otto Warburg's contributions to current concepts of cancer metabolism Nat. Rev. Cancer 11 2011 325 337
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 325-337
-
-
Koppenol, W.H.1
Bounds, P.L.2
Dang, C.V.3
-
19
-
-
78649711427
-
The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes
-
A.J. Levine, and A.M. Puzio-Kuter The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes Science 330 2010 1340 1344
-
(2010)
Science
, vol.330
, pp. 1340-1344
-
-
Levine, A.J.1
Puzio-Kuter, A.M.2
-
20
-
-
0026601537
-
Alternative forms of Max as enhancers or suppressors of Myc-ras cotransformation
-
T.P. Mäkelä, P.J. Koskinen, I. Västrik, and K. Alitalo Alternative forms of Max as enhancers or suppressors of Myc-ras cotransformation Science 256 1992 373 377
-
(1992)
Science
, vol.256
, pp. 373-377
-
-
Mäkelä, T.P.1
Koskinen, P.J.2
Västrik, I.3
Alitalo, K.4
-
21
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
V.K. Mootha, C.M. Lindgren, K.F. Eriksson, A. Subramanian, S. Sihag, J. Lehar, P. Puigserver, E. Carlsson, M. Ridderstråle, and E. Laurila PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes Nat. Genet. 34 2003 267 273
-
(2003)
Nat. Genet.
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstråle, M.9
Laurila, E.10
-
22
-
-
77249101567
-
Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence
-
A. Mukasa, J. Wykosky, K.L. Ligon, L. Chin, W.K. Cavenee, and F. Furnari Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence Proc. Natl. Acad. Sci. USA 107 2010 2616 2621
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 2616-2621
-
-
Mukasa, A.1
Wykosky, J.2
Ligon, K.L.3
Chin, L.4
Cavenee, W.K.5
Furnari, F.6
-
23
-
-
70449717544
-
Methods for analysis of brain tumor stem cell and neural stem cell self-renewal
-
I. Nakano, and H.I. Kornblum Methods for analysis of brain tumor stem cell and neural stem cell self-renewal Methods Mol. Biol. 568 2009 37 56
-
(2009)
Methods Mol. Biol.
, vol.568
, pp. 37-56
-
-
Nakano, I.1
Kornblum, H.I.2
-
24
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
D.W. Parsons, S. Jones, X. Zhang, J.C. Lin, R.J. Leary, P. Angenendt, P. Mankoo, H. Carter, I.M. Siu, and G.L. Gallia An integrated genomic analysis of human glioblastoma multiforme Science 321 2008 1807 1812
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
Mankoo, P.7
Carter, H.8
Siu, I.M.9
Gallia, G.L.10
-
25
-
-
77950490438
-
MADS+: Discovery of differential splicing events from Affymetrix exon junction array data
-
S. Shen, C.C. Warzecha, R.P. Carstens, and Y. Xing MADS+: discovery of differential splicing events from Affymetrix exon junction array data Bioinformatics 26 2010 268 269
-
(2010)
Bioinformatics
, vol.26
, pp. 268-269
-
-
Shen, S.1
Warzecha, C.C.2
Carstens, R.P.3
Xing, Y.4
-
26
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
A. Subramanian, P. Tamayo, V.K. Mootha, S. Mukherjee, B.L. Ebert, M.A. Gillette, A. Paulovich, S.L. Pomeroy, T.R. Golub, E.S. Lander, and J.P. Mesirov Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles Proc. Natl. Acad. Sci. USA 102 2005 15545 15550
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
27
-
-
79952749503
-
Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
-
Q. Sun, X. Chen, J. Ma, H. Peng, F. Wang, X. Zha, Y. Wang, Y. Jing, H. Yang, and R. Chen Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth Proc. Natl. Acad. Sci. USA 108 2011 4129 4134
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 4129-4134
-
-
Sun, Q.1
Chen, X.2
Ma, J.3
Peng, H.4
Wang, F.5
Zha, X.6
Wang, Y.7
Jing, Y.8
Yang, H.9
Chen, R.10
-
28
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
M.G. Vander Heiden, L.C. Cantley, and C.B. Thompson Understanding the Warburg effect: the metabolic requirements of cell proliferation Science 324 2009 1029 1033
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
29
-
-
0027339541
-
Alternative mRNA forms and open reading frames of the max gene
-
I. Västrik, P.J. Koskinen, R. Alitalo, and T.P. Mäkelä Alternative mRNA forms and open reading frames of the max gene Oncogene 8 1993 503 507
-
(1993)
Oncogene
, vol.8
, pp. 503-507
-
-
Västrik, I.1
Koskinen, P.J.2
Alitalo, R.3
Mäkelä, T.P.4
-
30
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Cancer Genome Atlas Research Network
-
R.G. Verhaak, K.A. Hoadley, E. Purdom, V. Wang, Y. Qi, M.D. Wilkerson, C.R. Miller, L. Ding, T. Golub, J.P. Mesirov Cancer Genome Atlas Research Network Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1 Cancer Cell 17 2010 98 110
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
Miller, C.R.7
Ding, L.8
Golub, T.9
Mesirov, J.P.10
|