The different clinical effects of anti-BLyS, anti-APRIL and anti-CD20 antibodies point at a critical pathogenic role of γ-herpesvirus infected b cells in the marmoset EAE model

Journal of Neuroimmune Pharmacology

Volumn 8, Issue 3, 2013, Pages 727-738

  Anwar Jagessar, S ^a,b   Fagrouch, Zahra ^a   Heijmans, Nicole ^a   Bauer, Jan ^c   Laman, Jon D ^b   Oh, Luke ^d   Migone, Thi ^d   Verschoor, Ernst J ^a   T'Hart, Bert A ^a,b,e  

^a BIOMEDICAL PRIMATE RESEARCH CENTRE   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d GLAXOSMITHKLINE   (United States)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

B cell; CalHV3; EBV; Experimental autoimmune encephalomyelitis; Marmoset; Multiple sclerosis

Indexed keywords

APRIL MONOCLONAL ANTIBODY; APRIL PROTEIN; B CELL ACTIVATING FACTOR; B CELL ACTIVATING FACTOR MONOCLONAL ANTIBODY; CD20 ANTIGEN; CD20 MONOCLONAL ANTIBODY; CD40 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 17; MONOCLONAL ANTIBODY; MYELIN AND LYMPHOCYTE PROTEIN; PLACEBO; UNCLASSIFIED DRUG; VIRUS DNA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CALLITRICHINAE; CELL GROWTH; CELL SURVIVAL; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; FEMALE; GAMMAHERPESVIRINAE; HERPES VIRUS INFECTION; IMMUNOTHERAPY; LYMPHOCYTE DEPLETION; LYMPHOCYTE TRANSFORMATION; LYMPHOID ORGAN; MALE; MENINGITIS; MULTIPLE SCLEROSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE ACTIVATION; VIRUS LOAD; VIRUS VIRULENCE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD20; B-CELL ACTIVATING FACTOR; B-LYMPHOCYTE SUBSETS; CALLITHRIX; CELL SURVIVAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GAMMAHERPESVIRINAE; HUMANS; MALE; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13;

EID: 84878792591     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-013-9448-6     Document Type: Article

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