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Volumn 6, Issue 5, 2013, Pages 960-971

Inhibition of N-terminal ATPase on HSP90 attenuates colitis through enhanced Treg function

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMINO TERMINAL TELOPEPTIDE; CD45RB ANTIGEN; DEXTRAN SULFATE; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HEAT SHOCK TRANSCRIPTION FACTOR 1; INTERLEUKIN 10; TANESPIMYCIN;

EID: 84878762023     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2012.134     Document Type: Article
Times cited : (46)

References (39)
  • 1
    • 0035180067 scopus 로고    scopus 로고
    • Control of intestinal inflammation by regulatory T cells
    • Singh, B. et al. Control of intestinal inflammation by regulatory T cells. Immunol. Rev. 182, 190-200 (2001
    • (2001) Immunol. Rev , vol.182 , pp. 190-200
    • Singh, B.1
  • 2
    • 0037446531 scopus 로고    scopus 로고
    • Cutting edge: Cure of colitis by CD4+CD25+ regulatory T cells
    • Mottet, C., Uhlig, H.H. & Powrie, F. Cutting edge: Cure of colitis by CD4+CD25+ regulatory T cells. J. Immunol. 170, 3939-3943 (2003
    • (2003) J. Immunol , vol.170 , pp. 3939-3943
    • Mottet, C.1    Uhlig, H.H.2    Powrie, F.3
  • 3
    • 0029586031 scopus 로고
    • Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)
    • Duchmann, R. et al. Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin. Exp. Immunol. 102, 448-455 (1995
    • (1995) Clin. Exp. Immunol , vol.102 , pp. 448-455
    • Duchmann, R.1
  • 4
    • 79956094244 scopus 로고    scopus 로고
    • Histone deacetylase 6 and heat shock protein 90 control the functions of foxp3+ T-regulatory cells
    • de Zoeten, E.F. et al. Histone deacetylase 6 and heat shock protein 90 control the functions of foxp3+ T-regulatory cells. Mol. Cell. Biol. 31, 2066-2078 (2011
    • (2011) Mol. Cell. Biol , vol.31 , pp. 2066-2078
    • De Zoeten, E.F.1
  • 5
    • 0034292391 scopus 로고    scopus 로고
    • Exaggerated human monocyte IL-10 concomitant to minimal TNF-Alpha induction by heatshock protein 27 (Hsp27) suggests Hsp27 is primarily an antiinflammatory stimulus
    • De, A.K., Kodys, K.M., Yeh, B.S. &Miller-Graziano, C. Exaggerated human monocyte IL-10 concomitant to minimal TNF-Alpha induction by heatshock protein 27 (Hsp27) suggests Hsp27 is primarily an antiinflammatory stimulus. J. Immunol. 165, 3951-3958 (2000
    • (2000) J. Immunol , vol.165 , pp. 3951-3958
    • De, A.K.1    Kodys, K.M.2    Yeh, B.S.3    Miller-Graziano, C.4
  • 6
    • 34848829167 scopus 로고    scopus 로고
    • Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis
    • Chatterjee, A. et al. Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis. Am. J. Respir. Crit. Care Med. 176, 667-675 (2007
    • (2007) Am. J. Respir. Crit. Care Med , vol.176 , pp. 667-675
    • Chatterjee, A.1
  • 7
    • 0037023695 scopus 로고    scopus 로고
    • Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6
    • Xie, Y., Chen, C., Stevenson, M.A., Auron, P.E. & Calderwood, S.K. Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6. J. Biol. Chem. 277, 11802-11810 (2002
    • (2002) J. Biol. Chem , vol.277 , pp. 11802-11810
    • Xie, Y.1    Chen, C.2    Stevenson, M.A.3    Auron, P.E.4    Calderwood, S.K.5
  • 8
    • 53149106311 scopus 로고    scopus 로고
    • Release of heat shock protein 70 and the effects of extracellular heat shock protein 70 on the production of IL-10 in fibroblast-like synoviocytes
    • Luo, X. et al. Release of heat shock protein 70 and the effects of extracellular heat shock protein 70 on the production of IL-10 in fibroblast-like synoviocytes. Cell Stress Chaperones 13, 365-373 (2008
    • (2008) Cell Stress Chaperones , vol.13 , pp. 365-373
    • Luo, X.1
  • 10
    • 34347380806 scopus 로고    scopus 로고
    • Heat shock protein gene 70-2 polymorphismis differentially associated with the clinical phenotypes of ulcerative colitis and Crohn's disease
    • Nam, S.Y. et al. Heat shock protein gene 70-2 polymorphismis differentially associated with the clinical phenotypes of ulcerative colitis and Crohn's disease. J. Gastroenterol. Hepatol. 22, 1032-1038 (2007
    • (2007) J. Gastroenterol. Hepatol , vol.22 , pp. 1032-1038
    • Nam, S.Y.1
  • 11
    • 34548171423 scopus 로고    scopus 로고
    • Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis
    • Tanaka, K. et al. Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis. J. Biol. Chem. 282, 23240-23252 (2007
    • (2007) J. Biol. Chem , vol.282 , pp. 23240-23252
    • Tanaka, K.1
  • 12
    • 0032555685 scopus 로고    scopus 로고
    • Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1
    • Zou, J., Guo, Y., Guettouche, T., Smith, D.F. & Voellmy, R. Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1. Cell 94, 471-480 (1998
    • (1998) Cell , vol.94 , pp. 471-480
    • Zou, J.1    Guo, Y.2    Guettouche, T.3    Smith, D.F.4    Voellmy, R.5
  • 13
    • 0033890818 scopus 로고    scopus 로고
    • Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding agents
    • Bagatell, R. et al. Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding agents. Clin. Cancer Res. 6, 3312-3318 (2000
    • (2000) Clin. Cancer Res , vol.6 , pp. 3312-3318
    • Bagatell, R.1
  • 14
    • 0035887917 scopus 로고    scopus 로고
    • Induction of IL-10 and inhibition of experimental arthritis are specific features of microbial heat shock proteins that are absent for other evolutionarily conserved immunodominant proteins
    • Prakken, B.J. et al. Induction of IL-10 and inhibition of experimental arthritis are specific features of microbial heat shock proteins that are absent for other evolutionarily conserved immunodominant proteins. J. Immunol. 167, 4147-4153 (2001
    • (2001) J. Immunol , vol.167 , pp. 4147-4153
    • Prakken, B.J.1
  • 15
    • 34347380341 scopus 로고    scopus 로고
    • Inhibition of Hsp90 attenuates inflammation in endotoxininduced uveitis
    • Poulaki, V. et al. Inhibition of Hsp90 attenuates inflammation in endotoxininduced uveitis. FASEB J. 21, 2113-2123 (2007
    • (2007) FASEB J , vol.21 , pp. 2113-2123
    • Poulaki, V.1
  • 16
    • 33750945303 scopus 로고    scopus 로고
    • The heat-shock protein 90 inhibitor 17-Allylamino-17- demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis
    • Dello Russo, C. et al. The heat-shock protein 90 inhibitor 17-Allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis. J. Neurochem. 99, 1351-1362 (2006
    • (2006) J. Neurochem , vol.99 , pp. 1351-1362
    • Dello Russo, C.1
  • 17
    • 0034711270 scopus 로고    scopus 로고
    • The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone
    • Marcu, M.G., Chadli, A., Bouhouche, I., Catelli, M. & Neckers, L.M. The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone. J. Biol. Chem. 275, 37181-37186 (2000
    • (2000) J. Biol. Chem , vol.275 , pp. 37181-37186
    • Marcu, M.G.1    Chadli, A.2    Bouhouche, I.3    Catelli, M.4    Neckers, L.M.5
  • 18
    • 84859756563 scopus 로고    scopus 로고
    • Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy
    • Tomasello, G. et al. Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy. Eur. J. Histochem. 55, e38 (2011
    • (2011) Eur. J. Histochem , vol.55
    • Tomasello, G.1
  • 19
    • 0031895351 scopus 로고    scopus 로고
    • The hsp90-based chaperone system: Involvement in signal transduction from a variety of hormone and growth factor receptors
    • Pratt, W.B. The hsp90-based chaperone system: Involvement in signal transduction from a variety of hormone and growth factor receptors. Proc. Soc. Exp. Biol. Med. 217, 420-434 (1998
    • (1998) Proc. Soc. Exp. Biol. Med , vol.217 , pp. 420-434
    • Pratt, W.B.1
  • 20
    • 0028179230 scopus 로고
    • Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity
    • Powrie, F., Correa-Oliveira, R., Mauze, S. & Coffman, R.L. Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. J. Exp. Med. 179, 589-600 (1994
    • (1994) J. Exp. Med , vol.179 , pp. 589-600
    • Powrie, F.1    Correa-Oliveira, R.2    Mauze, S.3    Coffman, R.L.4
  • 21
    • 0031993130 scopus 로고    scopus 로고
    • Interleukin 10 is a growth factor for a population of regulatory T cells
    • Asseman,C. & Powrie, F. Interleukin 10 is a growth factor for a population of regulatory T cells. Gut 42, 157-158 (1998
    • (1998) Gut , vol.42 , pp. 157-158
    • Asseman, C.1    Powrie, F.2
  • 22
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman, C., Mauze, S., Leach, M.W., Coffman, R.L. & Powrie, F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190, 995-1004 (1999
    • (1999) J. Exp. Med , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 23
    • 84863717726 scopus 로고    scopus 로고
    • Flt3 ligand expands CD103(+) dendritic cells and FoxP3(+) T regulatory cells, and attenuates Crohn's-like murine ileitis
    • Collins, C.B. et al. Flt3 ligand expands CD103(+) dendritic cells and FoxP3(+) T regulatory cells, and attenuates Crohn's-like murine ileitis. Gut 61, 1154-1162 (2012
    • (2012) Gut , vol.61 , pp. 1154-1162
    • Collins, C.B.1
  • 24
    • 0037315208 scopus 로고    scopus 로고
    • Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery
    • Pratt, W.B. & Toft, D.O. Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery. Exp. Biol. Med. (Maywood) 228, 111-133 (2003
    • (2003) Exp. Biol. Med. (Maywood , vol.228 , pp. 111-133
    • Pratt, W.B.1    Toft, D.O.2
  • 25
    • 58449116889 scopus 로고    scopus 로고
    • IL-10 is critically involved in mycobacterial HSP70 induced suppression of proteoglycan-induced arthritis
    • Wieten, L. et al. IL-10 is critically involved in mycobacterial HSP70 induced suppression of proteoglycan-induced arthritis. PLoS One 4, e41862009
    • PLoS One , vol.4
    • Wieten, L.1
  • 26
    • 82955169612 scopus 로고    scopus 로고
    • A compound that inhibits the HOPHsp90 complex formation and has unique killing effects in breast cancer cell lines
    • Pimienta, G.,Herbert, K.M. & Regan, L. A compound that inhibits the HOPHsp90 complex formation and has unique killing effects in breast cancer cell lines. Mol. Pharm. 8, 2252-2261 (2011
    • (2011) Mol. Pharm , vol.8 , pp. 2252-2261
    • Pimienta, G.1    Herbert, K.M.2    Regan, L.3
  • 27
    • 75449114277 scopus 로고    scopus 로고
    • Inhibition ofHDAC9 increases Tregulatory cell function and prevents colitis in mice
    • de Zoeten, E.F., Wang, L., Sai, H., Dillmann, W.H. & Hancock, W.W. Inhibition ofHDAC9 increases Tregulatory cell function and prevents colitis in mice. Gastroenterology 138, 583-594 (2010
    • (2010) Gastroenterology , vol.138 , pp. 583-594
    • De Zoeten, E.F.1    Wang, L.2    Sai, H.3    Dillmann, W.H.4    Hancock, W.W.5
  • 28
    • 54449101793 scopus 로고    scopus 로고
    • Heat shock transcription factor 1-Activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones
    • Fujikake, N. et al. Heat shock transcription factor 1-Activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones. J. Biol. Chem. 283, 26188-26197 (2008
    • (2008) J. Biol. Chem , vol.283 , pp. 26188-26197
    • Fujikake, N.1
  • 29
    • 8244262440 scopus 로고    scopus 로고
    • Effect of preinduction of heat shock proteins on acetic acid-induced colitis in rats
    • Otani, S. et al. Effect of preinduction of heat shock proteins on acetic acid-induced colitis in rats. Dig. Dis. Sci. 42, 833-846 (1997
    • (1997) Dig. Dis. Sci , vol.42 , pp. 833-846
    • Otani, S.1
  • 30
    • 34548416641 scopus 로고    scopus 로고
    • HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
    • Boyault, C. et al. HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates. Genes Dev. 21, 2172-2181 (2007
    • (2007) Genes Dev , vol.21 , pp. 2172-2181
    • Boyault, C.1
  • 31
    • 84866742738 scopus 로고    scopus 로고
    • HSF1 Is a Transcriptional Activator of IL-10 Gene Expression in RAW264.7 Macrophages
    • Zhang, H. et al. HSF1 Is a Transcriptional Activator of IL-10 Gene Expression in RAW264.7 Macrophages. Inflammation 35, 1558-1566 (2012
    • (2012) Inflammation , vol.35 , pp. 1558-1566
    • Zhang, H.1
  • 32
    • 67651063544 scopus 로고    scopus 로고
    • A role for HSP70 in protecting against indomethacininduced gastric lesions
    • Suemasu, S. et al. A role for HSP70 in protecting against indomethacininduced gastric lesions. J. Biol. Chem. 284, 19705-19715 (2009
    • (2009) J. Biol. Chem , vol.284 , pp. 19705-19715
    • Suemasu, S.1
  • 33
    • 0032949624 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce HSP70 in human monocytes
    • Housby, J.N. et al. Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce HSP70 in human monocytes. Cytokine 11, 347-358 (1999
    • (1999) Cytokine , vol.11 , pp. 347-358
    • Housby, J.N.1
  • 34
    • 33644872354 scopus 로고    scopus 로고
    • Phosphorylation of HSF1 by MAPK-Activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding
    • Wang, X. et al. Phosphorylation of HSF1 by MAPK-Activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding. J. Biol. Chem. 281, 782-791 (2006
    • (2006) J. Biol. Chem , vol.281 , pp. 782-791
    • Wang, X.1
  • 35
    • 35648990033 scopus 로고    scopus 로고
    • Diverse effects of Stat1 on the regulation of hsp90alpha gene under heat shock
    • Chen, X.S. et al. Diverse effects of Stat1 on the regulation of hsp90alpha gene under heat shock. J. Cell. Biochem. 102, 1059-1066 (2007
    • (2007) J. Cell. Biochem , vol.102 , pp. 1059-1066
    • Chen, X.S.1
  • 36
    • 79251588744 scopus 로고    scopus 로고
    • EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity
    • Yun, T.J. et al. EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity. J. Immunol. 186, 563-575 (2011
    • (2011) J. Immunol , vol.186 , pp. 563-575
    • Yun, T.J.1
  • 37
    • 40749161986 scopus 로고    scopus 로고
    • Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally
    • Zhang, Y. et al. Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally. Mol. Cell. Biol. 28, 1688-1701 (2008
    • (2008) Mol. Cell. Biol , vol.28 , pp. 1688-1701
    • Zhang, Y.1
  • 38
    • 33947622744 scopus 로고    scopus 로고
    • Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism
    • Smith, P. et al. Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism. J. Immunol. 178, 4557-4566 (2007
    • (2007) J. Immunol , vol.178 , pp. 4557-4566
    • Smith, P.1
  • 39
    • 80054852928 scopus 로고    scopus 로고
    • Retinoic acid attenuates ileitis by restoring the balance between t-helper 17 and t regulatory cells
    • Collins, C.B. et al. Retinoic acid attenuates ileitis by restoring the balance between T-helper 17 and T regulatory cells. Gastroenterology 141, 1821-1831 (2011
    • (2011) Gastroenterology , vol.141 , pp. 1821-1831
    • Collins, C.B.1


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