Cystatin C properties crucial for uptake and inhibition of intracellular target enzymes

Journal of Biological Chemistry

Volumn 288, Issue 23, 2013, Pages 17019-17029

  Wallin, Hanna ^a   Abrahamson, Magnus ^a   Ekstrom̈, Ulf ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CELL HOMOGENATE; CHARGED RESIDUES; CYSTEINE PROTEASE; CYSTEINE PROTEASE INHIBITORS; INTRACELLULAR ENZYME; INTRACELLULAR TARGET ENZYMES; PROSTATE CANCER CELLS; UPTAKE PROPERTIES;

AMINO ACIDS; CYTOLOGY; DISEASES; ENZYME ACTIVITY; ENZYME INHIBITION; EXPERIMENTS; PROTEINS;

CELLS;

CYSTATIN C; PROTEINASE;

AMINO ACID SUBSTITUTION; ARTICLE; BREAST ADENOCARCINOMA; CELL FREE SYSTEM; CELL STRAIN MCF 7; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME STRUCTURE; HUMAN; HUMAN CELL; INTERNALIZATION; MALE; METASTASIS; MICROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN FUNCTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TUMOR INVASION; WILD TYPE;

BREAST CANCER; CATHEPSIN B; CYSTEINE PROTEASE; ENDOCYTOSIS; LEGUMAIN; PROTEASE INHIBITOR; PROTEIN CHEMISTRY;

AMINO ACID SUBSTITUTION; BINDING SITES; CATHEPSIN D; CELL LINE, TUMOR; CYSTATIN C; CYSTEINE ENDOPEPTIDASES; HUMANS; LYSOSOMES; MUTATION, MISSENSE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOPLASMS;

EID: 84878759123     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.453449     Document Type: Article

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