Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone

Journal of Biological Chemistry

Volumn 288, Issue 23, 2013, Pages 16815-16826

  Schiefner, André ^a   Sinz, Quirin ^b   Neumaier, Irmgard ^a   Schwab, Wilfried ^b   Skerra, Arne ^a  

^a Munich Center for Integrated Protein Science   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCATALYTIC PROCESS; CRYSTALLOGRAPHIC ANALYSIS; ENOLATE INTERMEDIATES; ENZYMATIC FORMATION; MOLECULAR MECHANISM; PLANT SECONDARY METABOLISM; PROTEIN ENGINEERING; REACTIVE PRECURSORS;

CATALYSIS; FLAVOR COMPOUNDS; FRUITS; GENETIC ENGINEERING; REACTION PRODUCTS;

ENZYMES;

4 HYDROXY 2,5 DIMETHYL 3 (2H)FURANONE; ENONE OXIDOREDUCTASE; FLAVORING AGENT; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL LABELING; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME MECHANISM; ION TRANSPORT; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; REACTION TIME; STRAWBERRY; TAUTOMERIZATION; X RAY;

DEHYDROGENASE; ENONE OXIDOREDUCTASE; ENZYME MECHANISMS; ENZYME STRUCTURE; FURANEOL; NADPH; SECONDARY METABOLISM; X-RAY CRYSTALLOGRAPHY;

CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; FRAGARIA; FURANS; NAD(P)H DEHYDROGENASE (QUINONE); NADP; PLANT PROTEINS; PROTEIN FOLDING;

FRAGARIA X ANANASSA;

EID: 84878752841     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.453852     Document Type: Article

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