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Volumn 963, Issue , 2013, Pages 327-338

Nesfatin-1: Its role in the diagnosis and treatment of obesity and some psychiatric disorders

Author keywords

Calcium; EF hand; Nesfatin 1; Nucleobindin 2; Obesity

Indexed keywords

ANTIOBESITY AGENT; INSULIN; LEPTIN; MELANIN CONCENTRATING HORMONE; MELANOCORTIN; MESSENGER RNA; NESFAIN 1 RECEPTOR AGONIST; NESFATIN 1; NESFATIN 1 RELATED PEPTIDE; NUCLEOBINDIN 2; PEPTIDE; PROOPIOMELANOCORTIN; UNCLASSIFIED DRUG; CALCIUM BINDING PROTEIN; DNA BINDING PROTEIN; NERVE PROTEIN; NUCLEOBINDIN;

EID: 84878748689     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-230-8_20     Document Type: Chapter
Times cited : (13)

References (33)
  • 1
    • 18344390264 scopus 로고    scopus 로고
    • The brain-adipose axis
    • Shimizu H, Mori M (2005) The brain-adipose axis. Nutr Neurosci 8:7–20.
    • (2005) Nutr Neurosci , vol.8 , pp. 7-20
    • Shimizu, H.1    Mori, M.2
  • 2
    • 3543001598 scopus 로고    scopus 로고
    • Troglitazone reduces plasma leptin concentration but increases hunger in NIDDM patients
    • Shimizu H, Tsuchiya T, Sato N et al (1998) Troglitazone reduces plasma leptin concentration but increases hunger in NIDDM patients. Diabetes Care 21:1470–1474.
    • (1998) Diabetes Care , vol.21 , pp. 1470-1474
    • Shimizu, H.1    Tsuchiya, T.2    Sato, N.3
  • 3
    • 33749859790 scopus 로고    scopus 로고
    • Identi fication of nesfatin-1 as a satiety molecule in the hypothalamus
    • Oh-I S, Shimizu H, Satoh T et al (2006) Identi fication of nesfatin-1 as a satiety molecule in the hypothalamus. Nature 443:709–712.
    • (2006) Nature , vol.443 , pp. 709-712
    • Oh-I, S.1    Shimizu, H.2    Satoh, T.3
  • 4
    • 77954526102 scopus 로고    scopus 로고
    • Troglitazone, a ligand of peroxisome proliferator-activated receptor-g, stabilizes NUCB2 (Nesfatin) mRNA by activating the ERK1/2 pathway: Isolation and characterization of the human NUCB2 gene
    • Yamada M, Horiguchi K, Umezawa R et al (2010) Troglitazone, a ligand of peroxisome proliferator-activated receptor-g, stabilizes NUCB2 (Nesfatin) mRNA by activating the ERK1/2 pathway: isolation and characterization of the human NUCB2 gene. Endocrinology 151:2494–2503.
    • (2010) Endocrinology , vol.151 , pp. 2494-2503
    • Yamada, M.1    Horiguchi, K.2    Umezawa, R.3
  • 5
    • 34748902793 scopus 로고    scopus 로고
    • Nesfatin-1: Distribution and interaction with a G protein-coupled receptor in the rat brain
    • Brailoiu GC, Dun SL, Braoiu E et al (2007) Nesfatin-1: distribution and interaction with a G protein-coupled receptor in the rat brain. Endocrinology 148:5088–5094.
    • (2007) Endocrinology , vol.148 , pp. 5088-5094
    • Brailoiu, G.C.1    Dun, S.L.2    Braoiu, E.3
  • 6
    • 54049152736 scopus 로고    scopus 로고
    • Nesfatin-1 increases anxiety- and fear-related behaviors in the rat
    • Merali Z, Cayer C, Kent P et al (2008) Nesfatin-1 increases anxiety- and fear-related behaviors in the rat. Psychopharmacology (Berl) 201:115–123.
    • (2008) Psychopharmacology (Berl) , vol.201 , pp. 115-123
    • Merali, Z.1    Cayer, C.2    Kent, P.3
  • 7
    • 35348968303 scopus 로고    scopus 로고
    • Nesfatin-1 crosses the blood–brain barrier without saturation
    • Pan W, Hsuchou H, Kastin AJ (2007) Nesfatin-1 crosses the blood–brain barrier without saturation. Peptides 28:2223–2228.
    • (2007) Peptides , vol.28 , pp. 2223-2228
    • Pan, W.1    Hsuchou, H.2    Kastin, A.J.3
  • 8
    • 36249030596 scopus 로고    scopus 로고
    • Permeability of the blood–brain barrier to a novel satiety molecule nesfatin-1
    • Price TO, Samson WK, NiehoffML et al (2007) Permeability of the blood–brain barrier to a novel satiety molecule nesfatin-1. Peptides 28:2372–2381.
    • (2007) Peptides , vol.28 , pp. 2372-2381
    • Price, T.O.1    Samson, W.K.2    Niehoff, M.L.3
  • 9
    • 26944442471 scopus 로고    scopus 로고
    • Molecular mechanisms associated with leptin resistance: n-3 polyunsaturated fatty acids induce alterations in the tight junction of the brain
    • Oh-I S, Shimizu H, Satoh T et al (2005) Molecular mechanisms associated with leptin resistance: n-3 polyunsaturated fatty acids induce alterations in the tight junction of the brain. Cell Metab 1:331–341.
    • (2005) Cell Metab , vol.1 , pp. 331-341
    • Oh-I, S.1    Shimizu, H.2    Satoh, T.3
  • 10
    • 68449094576 scopus 로고    scopus 로고
    • Nesfatin-1: An overview and future clinical application
    • Shimizu H, Oh-I S, Okada S et al (2009) Nesfatin-1: an overview and future clinical application. Endocr J 56:537–543.
    • (2009) Endocr J , vol.56 , pp. 537-543
    • Shimizu, H.1    Oh-I, S.2    Okada, S.3
  • 11
    • 59649122740 scopus 로고    scopus 로고
    • Peripheral administration of nesfatin-1 reduces food intake in mice: the leptin-independent mechanism
    • Shimizu H, Oh-I S, Hashimoto K et al (2009) Peripheral administration of nesfatin-1 reduces food intake in mice: the leptin-independent mechanism. Endocrinology 150:662–671.
    • (2009) Endocrinology , vol.150 , pp. 662-671
    • Shimizu, H.1    Oh-I, S.2    Hashimoto, K.3
  • 12
    • 40849142341 scopus 로고    scopus 로고
    • Nesfatin-1 neurons in paraventricular and supraoptic nuclei of the hypothalamus coexpress oxytocin and vasopressin and are activated by refeeding
    • Kohno D, Nakata M, Maejima Y et al (2008) Nesfatin-1 neurons in paraventricular and supraoptic nuclei of the hypothalamus coexpress oxytocin and vasopressin and are activated by refeeding. Endocrinology 149:1295–1301.
    • (2008) Endocrinology , vol.149 , pp. 1295-1301
    • Kohno, D.1    Nakata, M.2    Maejima, Y.3
  • 13
    • 38549098256 scopus 로고    scopus 로고
    • Nesfatin-1 in fluences the excitability of paraventricular nucleus neurons
    • Price CJ, Hoyda TD, Samson WK et al (2008) Nesfatin-1 in fluences the excitability of paraventricular nucleus neurons. J Neuroendocrinol 20:245–250.
    • (2008) J Neuroendocrinol , vol.20 , pp. 245-250
    • Price, C.J.1    Hoyda, T.D.2    Samson, W.K.3
  • 14
    • 34347333390 scopus 로고    scopus 로고
    • Neuroendocrine mechanism of change in food intake during pregnancy: A potential role for brain oxytocin
    • Douglas AJ, Johnstone LE, Leng G (2007) Neuroendocrine mechanism of change in food intake during pregnancy: a potential role for brain oxytocin. Physiol Behav 91:352–365.
    • (2007) Physiol Behav , vol.91 , pp. 352-365
    • Douglas, A.J.1    Johnstone, L.E.2    Leng, G.3
  • 15
    • 54049126084 scopus 로고    scopus 로고
    • Nesfatin-1 inhibits NPY neurons in the arcuate nucleus
    • Price CJ, Samson WK, Ferguson AV (2008) Nesfatin-1 inhibits NPY neurons in the arcuate nucleus. Brain Res 1230:99–106.
    • (2008) Brain Res , vol.1230 , pp. 99-106
    • Price, C.J.1    Samson, W.K.2    Ferguson, A.V.3
  • 16
    • 56149100976 scopus 로고    scopus 로고
    • Desacyl ghrelin inhibits the orexigenic effect of peripherally injected ghrelin in rats
    • InhoffT, Mönnikes H, Noetzel S et al (2008) Desacyl ghrelin inhibits the orexigenic effect of peripherally injected ghrelin in rats. Peptides 29:2159–2168.
    • (2008) Peptides , vol.29 , pp. 2159-2168
    • Inhoff, T.1    Mönnikes, H.2    Noetzel, S.3
  • 17
    • 47249096974 scopus 로고    scopus 로고
    • The satiety molecule nesfatin-1 is co-expressed with melanin concentrating hormone in tuberal hypothalamic neurons of the rat
    • Fort P, Salvert D, Hanriot L et al (2008) The satiety molecule nesfatin-1 is co-expressed with melanin concentrating hormone in tuberal hypothalamic neurons of the rat. Neuroscience 155:174–178.
    • (2008) Neuroscience , vol.155 , pp. 174-178
    • Fort, P.1    Salvert, D.2    Hanriot, L.3
  • 18
    • 53249107183 scopus 로고    scopus 로고
    • Distribution and neuropeptide coexistence of nucleobindin-2 mRNA/nesfatin-like immunoreactivity in the rat CNS
    • Foo KS, Brismar H, Broberger C (2008) Distribution and neuropeptide coexistence of nucleobindin-2 mRNA/nesfatin-like immunoreactivity in the rat CNS. Neuroscience 156:563–579.
    • (2008) Neuroscience , vol.156 , pp. 563-579
    • Foo, K.S.1    Brismar, H.2    Broberger, C.3
  • 19
    • 58149466993 scopus 로고    scopus 로고
    • Identi fication and characterization of nesfatin-1 immunoreactivity in endocrine cell types of the rat gastric oxyntic mucosa
    • Stengel A, Goebel M, Yakubov I et al (2009) Identi fication and characterization of nesfatin-1 immunoreactivity in endocrine cell types of the rat gastric oxyntic mucosa. Endocrinology 150:232–238.
    • (2009) Endocrinology , vol.150 , pp. 232-238
    • Stengel, A.1    Goebel, M.2    Yakubov, I.3
  • 20
    • 0030038404 scopus 로고    scopus 로고
    • Identi fication and expression of prohormoneconverting enzymes in the rat stomach
    • Macro JA, Dimaline R, Dockray GJ (1996) Identi fication and expression of prohormoneconverting enzymes in the rat stomach. Am J Physiol 270:G87–G93.
    • (1996) Am J Physiol , vol.270 , pp. G87-G93
    • Macro, J.A.1    Dimaline, R.2    Dockray, G.J.3
  • 21
    • 0036787457 scopus 로고    scopus 로고
    • The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats
    • Date Y, Murakami N, Toshinai K et al (2002) The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroenterology 123: 1120–1128.
    • (2002) Gastroenterology , vol.123 , pp. 1120-1128
    • Date, Y.1    Murakami, N.2    Toshinai, K.3
  • 22
    • 67349224649 scopus 로고    scopus 로고
    • A new anorexigenic protein, nesfatin-1
    • Shimizu H, Ohsaki A, Oh-I S et al (2009) A new anorexigenic protein, nesfatin-1. Peptides 30:995–998.
    • (2009) Peptides , vol.30 , pp. 995-998
    • Shimizu, H.1    Ohsaki, A.2    Oh-I, S.3
  • 23
    • 62649109918 scopus 로고    scopus 로고
    • Pancreatic beta cells colocalize insulin and pronesfatin immunoreactivity in rodents
    • Gonzalez R, Tiwari A, Unniappan S (2009) Pancreatic beta cells colocalize insulin and pronesfatin immunoreactivity in rodents. Biochem Biophys Res Commun 381:643–648.
    • (2009) Biochem Biophys Res Commun , vol.381 , pp. 643-648
    • Gonzalez, R.1    Tiwari, A.2    Unniappan, S.3
  • 24
    • 79955764199 scopus 로고    scopus 로고
    • 2+ in flux through L-type channels in mouse islet b-cells
    • 2+ in flux through L-type channels in mouse islet b-cells. Endocr J 58:305–313.
    • (2011) Endocr J , vol.58 , pp. 305-313
    • Nakata, M.1    Manaka, K.2    Yamamoto, S.3
  • 25
    • 80053143982 scopus 로고    scopus 로고
    • Nutrient responsive nesfatin-1 regulates energy balance and induces glucose-stimulated insulin secretion in rats
    • Gonzalez R, Perry RL, Gao X et al (2011) Nutrient responsive nesfatin-1 regulates energy balance and induces glucose-stimulated insulin secretion in rats. Endocrinology 152:3628–3637.
    • (2011) Endocrinology , vol.152 , pp. 3628-3637
    • Gonzalez, R.1    Perry, R.L.2    Gao, X.3
  • 26
    • 84856758557 scopus 로고    scopus 로고
    • Nesfatin-1 stimulates glucagon and insulin secretion and beta cell NUCB2 is reduced in human type 2 diabetic subjects
    • Riva M, Dekker M, Voss U et al (2011) Nesfatin-1 stimulates glucagon and insulin secretion and beta cell NUCB2 is reduced in human type 2 diabetic subjects. Cell Tissue Res 346:393–405.
    • (2011) Cell Tissue Res , vol.346 , pp. 393-405
    • Riva, M.1    Dekker, M.2    Voss, U.3
  • 27
    • 77957036661 scopus 로고    scopus 로고
    • Fasting concentrations of nesfatin-1 are negatively correlated with body mass index in nonobese males
    • Tsuchiya T, Shimizu H, Yamada M et al (2010) Fasting concentrations of nesfatin-1 are negatively correlated with body mass index in nonobese males. Clin Endocrinol 73:484–490.
    • (2010) Clin Endocrinol , vol.73 , pp. 484-490
    • Tsuchiya, T.1    Shimizu, H.2    Yamada, M.3
  • 28
    • 71349086261 scopus 로고    scopus 로고
    • Fasting plasma levels of nesfatin-1 in patients with type 1 and type 2 diabetes mellitus and the nutrientrelated fluctuation of nesfatin-1 level in normal humans
    • Lo QC, Wang HY, Chen X et al (2010) Fasting plasma levels of nesfatin-1 in patients with type 1 and type 2 diabetes mellitus and the nutrientrelated fluctuation of nesfatin-1 level in normal humans. Regul Pept 8:72–77.
    • (2010) Regul Pept , vol.8 , pp. 72-77
    • Lo, Q.C.1    Wang, H.Y.2    Chen, X.3
  • 29
    • 84857062896 scopus 로고    scopus 로고
    • Increased plasma levels of nesfatin-1 in patients with newly diagnosed type 2 diabetes mellitus
    • Zhang Z, Li L, Yang M et al (2012) Increased plasma levels of nesfatin-1 in patients with newly diagnosed type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes 120:91–95.
    • (2012) Exp Clin Endocrinol Diabetes , vol.120 , pp. 91-95
    • Zhang, Z.1    Li, L.2    Yang, M.3
  • 30
    • 67650246579 scopus 로고    scopus 로고
    • Nesfatin-1 and ghrelin levels in serum and saliva of epileptic patients: Hormonal changes can have a major effect on seizure disorders
    • Aydin S, Dag E, Ozkan Y et al (2009) Nesfatin-1 and ghrelin levels in serum and saliva of epileptic patients: hormonal changes can have a major effect on seizure disorders. Mol Cell Biochem 32:49–56.
    • (2009) Mol Cell Biochem , vol.32 , pp. 49-56
    • Aydin, S.1    Dag, E.2    Ozkan, Y.3
  • 31
    • 79952901983 scopus 로고    scopus 로고
    • High plasma nesfatin-1 level in patients with major depressivedisorder
    • Ari M, Ozturk OH, Bez Y et al (2010) High plasma nesfatin-1 level in patients with major depressivedisorder. ProgNeuropsychopharmacol Biol Psychiatry 35:497–500.
    • (2010) Progneuropsychopharmacol Biol Psychiatry , vol.35 , pp. 497-500
    • Ari, M.1    Ozturk, O.H.2    Bez, Y.3
  • 32
    • 0032747280 scopus 로고    scopus 로고
    • Recombinant leptin for weight loss in obese and lean adults: A randomized, controlled, dose-escalation trial
    • Heyms field SB, Greeberg AS, Fujioka K et al (1999) Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial. JAMA 282:1568–1575.
    • (1999) JAMA , vol.282 , pp. 1568-1575
    • Heyms fiEld, S.B.1    Greeberg, A.S.2    Fujioka, K.3
  • 33
    • 79953858161 scopus 로고    scopus 로고
    • Decreased cerebrospinal fluid/plasma ratio of the novel satiety molecule, nesfatin-1/NUCB-2, in obese humans: Evidence of nesfatin-1/ NUCB-2 resistance and implications for obesity treatment
    • Tan BK, Hallschmid M, Kern W et al (2011) Decreased cerebrospinal fluid/plasma ratio of the novel satiety molecule, nesfatin-1/NUCB-2, in obese humans: evidence of nesfatin-1/ NUCB-2 resistance and implications for obesity treatment. J Clin Endocrinol Metab 96:E669–E673.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. E669-E673
    • Tan, B.K.1    Hallschmid, M.2    Kern, W.3


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