Verbal working memory in individuals with schizophrenia and their first degree relatives: Relationship with negative and disorganized symptoms

Actas Espanolas de Psiquiatria

Volumn 41, Issue 2, 2013, Pages 106-114

  Botero, Sonia ^a   Muñoz, Claudia C ^a   Ocampo, María V ^b   Escobar, Marcela ^a   Rangel, Andrés ^a   Quintero, Claudia ^a   Marin, Catalina ^b   Jaramillo, Luis E ^c   Sánchez, Ricardo ^c   Rodríguez Losada, Jorge ^c   Beltrán, Diana ^c   Ospina, Jorge ^a   Palacio, Carlos ^a   Arango, Juan C ^a   Aguirre Acevedo, Daniel C ^a   Páez, Ana Lucia ^a   Valencia, Ana V ^b   Garcia, Jenny ^a  

^a UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^b UNIVERSIDAD PONTIFICIA BOLIVARIANA   (Colombia)

^c UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

Author keywords

Disorganized symptoms; Endophenotype; Negative symptoms; Schizophrenia; Verbal working memory

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CROSS-SECTIONAL STUDY; FEMALE; GENETICS; HEBEPHRENIA; HUMAN; MALE; MIDDLE AGED; PSYCHOLOGICAL ASPECT; PSYCHOLOGY; SCHIZOPHRENIA; SHORT TERM MEMORY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MEMORY, SHORT-TERM; MIDDLE AGED; SCHIZOPHRENIA; SCHIZOPHRENIA, DISORGANIZED; SCHIZOPHRENIC PSYCHOLOGY; YOUNG ADULT;

EID: 84878740174     PISSN: 11399287     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Cannon TD, Kaprio J, Lonnqvist J, Huttunen M, Koskenvuo M. The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study. Arch Gen Psychiatry. 1998 Jan; 55(1):67-74. (Pubitemid 28069041)
2. Girard SL, Dion PA, Rouleau GA. Schizophrenia genetics: putting all the pieces together. Curr Neurol Neurosci Rep. 2012 Jun; 12(3):261-6.
3. Keshavan MS, Nasrallah HA, Tandon R. Schizophrenia, "Just the Facts" 6. Moving ahead with the schizophrenia concept: from the elephant to the mouse. Schizophr Res. 2011 Apr; 127(1-3):3-13.
4. Nasrallah H, Tandon R, Keshavan M. Beyond the facts in schizophrenia: closing the gaps in diagnosis, pathophysiology, and treatment. Epidemiol Psychiatr Sci. 2011 Dec; 20(4):317-27.
5. Cannon TD. The inheritance of intermediate phenotypes for schizophrenia. Curr Opin Psychiatry. 2005 Mar; 18(2):135-40. (Pubitemid 40824444)
6. Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003 Apr; 160(4):636-45. (Pubitemid 41079594)
7. Braff DL, Freedman R, Schork NJ, Gottesman II. Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophr Bull. 2007 Jan; 33(1):21-32. (Pubitemid 46026257)
8. Braff DL, Greenwood TA, Swerdlow NR, Light GA, Schork NJ. Advances in endophenotyping schizophrenia. World Psychiatry. 2008 Feb; 7(1):11-8. (Pubitemid 351338180)
9. Gur RE, Calkins ME, Gur RC, Horan WP, Nuechterlein KH, Seidman U, et al. The Consortium on the Genetics of Schizophrenia: neurocognitive endophenotypes. Schizophr Bull. 2007 Jan; 33(1):49-68. (Pubitemid 46026259)
10. Perry W, Heaton RK, Potterat E, Roebuck T, Minassian A, Braff DL Working memory in schizophrenia: transient "online" storage versus executive functioning. Schizophr Bull. 2001;27(1):157-76. (Pubitemid 32199271)
11. Gold JM, Carpenter C, Randolph C, Goldberg TE, Weinberger DR. Auditory working memory and Wisconsin Card Sorting Test performance in schizophrenia. Arch Gen Psychiatry. 1997 Feb; 54(2):159-65. (Pubitemid 27074304)
12. Forbes NF, Carrick LA, Mcintosh AM, Lawrie SM. Working memory in schizophrenia: a meta-analysis. Psychol Med. 2009 Jun; 39(6):889-905.
13. Kim J, Glahn DC, Nuechterlein KH, Cannon TD. Maintenance and manipulation of information in schizophrenia: further evidence for impairment in the central executive component of working memory. Schizophr Res. 2004 Jun. 1;68(2-3):173-87. (Pubitemid 38526141)
14. Ojeda N, Pena J, Sehretlen DJ, Sanchez P, Aretouli E, Elizagarate E, et al. Hierarchical structure of the cognitive processes in schizophrenia: the fundamental role of processing speed. Schizophr Res. 2012 Mar; 135(1-3):72-8.
15. Glahn DC, Almasy L, Blangero J, Burk GM, Estrada J, Peralta JM, et al. Adjudicating neurocognitive endophenotypes for schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2007 Mar 5;144 B (2): 242-9. (Pubitemid 46606651)
16. Conklin HM, Curtis CE, Calkins ME, Iacono WG. Working memory functioning in schizophrenia patients and their firstdegree relatives: cognitive functioning shedding light on etiology. Neuropsychologia. 2005;43(6):930-42. (Pubitemid 40248900)
17. Horan WP, Braff DL, Nuechterlein KH, Sugar CA, Cadenhead KS, Calkins ME, et al. Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia. Schizophr Res. 2008 Aug; 103(1-3):218-28.
18. Barrantes-Vidal N, Aguilera M, Campanera S, Fatjo-Vilas M, Guitart M, Miret S, et al. Working memory in siblings of schizophrenia patients. Schizophr Res. 2007 Sep; 95(1-3):70-5. (Pubitemid 47313656)
19. Conklin HM, Curtis CE, Katsanis J, Iacono WG. Verbal working memory impairment in schizophrenia patients and their firstdegree relatives: evidence from the digit span task. Am J Psychiatry. 2000 Feb; 157(2):275-7. (Pubitemid 30080912)
20. Torniainen M, Suvisaari J, Partonen T, Castaneda AE, Kuha A, Suokas J, et al. Cognitive impairments in schizophrenia and schizoaffective disorder: relationship with clinical characteristics. J Nerv Ment Dis. 2012 Apr; 200(4):316-22.
21. Daban C, Amado I, Bayle F, Gut A, Willard D, Bourdel MC, et al. Disorganization syndrome is correlated to working memory deficits in unmedicated schizophrenic patients with recent onset schizophrenia. Schizophr Res. 2003 Jun. 1;61(2-3):323-4. (Pubitemid 36513943)
22. Twamley EW, Palmer BW, Jeste DV, Taylor MJ, Heaton RK. Transient and executive function working memory in schizophrenia. Schizophr Res. 2006 Oct; 87(1-3):185-90. (Pubitemid 44467853)
23. Scala S, Lasalvia A, Cristofalo D, Bonetto C, Ruggeri M. Neurocognitive profile and its association with psychopathology in first-degree relatives of patients with schizophrenia. A casecontrol study. Psychiatry Res. 2012 May 29.
24. Delawalla Z, Barch DM, Fisher Eastep JL, Thomason ES, Hanewinkel MJ, Thompson PA, et al. Factors mediating cognitive deficits and psychopathology among siblings of individuals with schizophrenia. Schizophr Bull. 2006 Jul; 32(3):525-37. (Pubitemid 43992326)
25. Vollema MG, Postma B. Neurocognitive correlates of schizotypy in first degree relatives of schizophrenia patients. Schizophr Bull. 2002;28(3):367-77. (Pubitemid 36193857)
26. Remberk B, Namyslowska I, Rybakowski F. Cognitive impairment and formal thought disorders in parents of earlyonset schizophrenia patients. Neuropsychobiology. 2012 Jun; 65(4):206-15.
27. American Psychiatric Association. Manual Diagnostico y Estadistico de Trastornos Mentales: Cuarta Edition Texto Revisado. 4 ed. Washington D. C.: Masson, 2000.
28. Nurnberger JI Jr., Blehar MC, Kaufmann CA, York-Cooler C, Simpson SG, Harkavy-Friedman J, et al. Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative. Arch Gen Psychiatry. 1994 Nov; 51(11):849-59. (Pubitemid 24985906)
29. Andreasen NC. Scales for the assessment of positive symptoms (SAPS). Iowa: University of Iowa, 1984.
30. Andreasen NC. The Scale for the Assessment of Negative Symptoms (SANS): conceptual and theoretical foundations. Br J Psychiatry. Suppl 1989 Nov; (7): 49-58.
31. Palacio CA, Garcia J, Arbelaez MP, Sanchez R, Aguirre B, Garces IC, et al. Validation of the Diagnostic Interview for Genetic Studies (DIGS) in Colombia. Biomedica. 2004 Mar; 24(1):56-62.
32. Garcia J, Palacio CA, Garcés IC, Arbeláez MP, Sánchez R, López CA. Inferencias fenomenológicas y nosologicas en la esquizofrenia a partir de la validación de las escalas de sintomas positivos (SAPS) y de sintomas negativos (SANS) en Colombia. Revista de Neuro-Psiquiatria. 2003;66:195-214.
33. Wechsler D. Escala Wechsler de Inteligencia para Adultos - III (WAIS - III). Mexico D. F.: Manual Moderno, 2001.
34. Nuechterlein KH, Green MF, Kern RS, Baade LE, Barch DM, Cohen JD, et al. The MATRICS Consensus Cognitive Battery, part 1: test selection, reliability, and validity. Am J Psychiatry, 2008 Feb; 165(2):203-13. (Pubitemid 351704520)
35. Cohen J. Statistical power analysis for the behavioral sciences. 2 ed. Hillsdale: Lawrence Earlbaum Associates, 1988.
36. Frith C, Dolan R. The role of the prefrontal cortex in higher cognitive functions. Brain Res Cogn Brain Res. 1996 Dec; 5(1-2):175-81. (Pubitemid 27095250)
37. Egan MF, Goldberg TE, Gscheidle T, Weirich M, Rawlings R, Hyde TM, et al. Relative risk for cognitive impairments in siblings of patients with schizophrenia. Biol Psychiatry. 2001 Jul. 15;50(2):98-107. (Pubitemid 32728209)
38. MacDonald AW, III, Thermenos HW, Barch DM, Seidman U. Imaging genetic liability to schizophrenia: systematic review of FMRI studies of patients' nonpsychotic relatives. Schizophr Bull. 2009 Nov; 35(6):1142-62.
39. Husted JA, Lim S, Chow EW, Greenwood C, Bassett AS. Heritability of neurocognitive traits in familial schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2009 Sep. 5;150 B (6): 845-53.
40. Tuulio-Henriksson A, Haukka J, Partonen T, Varilo T, Paunio T, Ekelund J, et al. Heritability and number of quantitative trait loci of neurocognitive functions in families with schizophrenia. Am J Med Genet. 2002 Jul. 8;114(5):483-90. (Pubitemid 34680572)
41. Tuulio-Henriksson A, Partonen T. Suvisaari J, Haukka J, Lonnqvist J. Age at onset and cognitive functioning in schizophrenia. Br J Psychiatry. 2004 Sep; 185:215-9. (Pubitemid 39208222)
42. Barch DM, Carter CS, Braver TS, Sabb FW, Macdonald A, III, Noll DC, et al. Selective deficits in prefrontal cortex function in medication-naive patients with schizophrenia. Arch Gen Psychiatry. 2001 Mar; 58(3):280-8. (Pubitemid 32209682)
43. Van Veelen NM, Vink M, Ramsey NF, Kahn RS. Left dorsolateral prefrontal cortex dysfunction in medication-naive schizophrenia. Schizophr Res. 2010 Oct; 123(1):22-9.
44. Greenwood KE, Morris R, Sigmundsson T, Landau S, Wykes T. Executive functioning in schizophrenia and the relationship with symptom profile and chronicity. J Int Neuropsychol Soc. 2008 Sep; 14(5):782-92.