Hierarchical structure of the cognitive processes in schizophrenia: The fundamental role of processing speed

Schizophrenia Research

Volumn 135, Issue 1-3, 2012, Pages 72-78

  Ojeda, N ^a,b   Pena J ^a   Schretlen, D J ^c   Sanchez P ^d,e   Aretouli, E ^a   Elizagarate E ^b,d,e   Ezcurra, J ^d   Gutierrez M ^b,e,f  

^a UNIVERSITY OF DEUSTO   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE SALUD MENTAL CIBERSAM   (Spain)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Hospital Psiquiatrico de Alava   (Spain)

^e UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^f Hospital Santiago   (Spain)

Author keywords

Chronic schizophrenia; Neurocognition; Processing speed

Indexed keywords

ARIPIPRAZOLE; FLUPHENAZINE DECANOATE; HALOPERIDOL; OLANZAPINE; QUETIAPINE; RISPERIDONE;

ADULT; ARTICLE; ATTENTION; CHRONIC DISEASE; CLINICAL FEATURE; COGNITIVE DEFECT; CONTROLLED STUDY; EXECUTIVE FUNCTION; FACTORIAL ANALYSIS; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL CAPACITY; MENTAL PERFORMANCE; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; PSYCHOPATHY; SCHIZOPHRENIA; SYMPTOM; VERBAL MEMORY; VISUAL MEMORY; WORKING MEMORY;

ADULT; ATTENTION; CHI-SQUARE DISTRIBUTION; COGNITION DISORDERS; EXECUTIVE FUNCTION; FACTOR ANALYSIS, STATISTICAL; FEMALE; HUMANS; MALE; MEMORY; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA; VERBAL LEARNING;

EID: 84857235422     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2011.12.004     Document Type: Article

References (44)

1. Addington D., Addington J., Schissel B. A depression rating scale for schizophrenics. Schizophr. Res. 1990, 3(4):247-251.
2. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders DSM-IV 1994, American Psychiatric Association, Washington, DC. 4th ed. American Psychiatric Association (Ed.).
3. Andreasen N.C., Pressler M., Nopoulos P., Miller D., Ho B.-C. Antipsychotic dose equivalents and dose-years: a standardized method for comparing exposure to different drugs. Biol. Psychiatry 2010, 67(3):255-262.
4. Appels M.C., Sitskoorn M.M., Westers P., Lems E., Kahn R.S. Cognitive dysfunctions in parents of schizophrenic patients parallel the deficits found in patients. Schizophr. Res. 2003, 63(3):285-293.
5. Bentler P.M., Bonett D.G. Significance tests and goodness of fit in the analysis of covariance structures. Psychol. Bull. 1980, 88(3):588-606.
6. Bowie C.R., Leung W.W., Reichenberg A., McClure M.M., Patterson T.L., Heaton R.K., Harvey P.D. Predicting schizophrenia patients' real-world behavior with specific neuropsychological and functional capacity measures. Biol. Psychiatry 2008, 63(5):505-511.
7. Brebion G., David A.S., Bressan R.A., Pilowsky L.S. Processing speed: a strong predictor of verbal memory performance in schizophrenia. J. Clin. Exp. Neuropsychol. 2006, 28(3):370-382.
8. Byrne B.M. Structural Equation Modeling with LISREL, PRELIS, and SIMPLIS: Basic Concepts, Applications, and Programming 1998, Lawrence Erlbaum Associates Publishers, Mahwah, NJ US.
9. Carmines E.G., McIver J.P. Analyzing models with unobserved variables: analysis of covariance structures. Social Measurement: Current Issues. B 1981, Sage, Hills. E.F. Bornstedt, E.F. Borgatta (Eds.).
10. Colom F., Vieta E., Martinez-Arán A., García-García M., Reinares M., Torrent C., Goikolea J.M., Banús S., Salamero M. Versión española de una escala de evaluación de la manía. validez y fiabilidad de la escala young. Med. Clin. 2002, 119:366-371.
11. Dickinson D., Ragland J.D., Calkins M.E., Gold J.M., Gur R.C. A comparison of cognitive structure in schizophrenia patients and healthy controls using confirmatory factor analysis. Schizophr. Res. 2006, 85(1-3):20-29.
12. Dickinson D., Ragland J.D., Gold J.M., Gur R.C. General and specific cognitive deficits in schizophrenia: Goliath defeats David?. Biol. Psychiatry 2008, 64(9):823-827.
13. Dickinson D., Ramsey M.E., Gold J.M. Overlooking the obvious: a meta-analytic comparison of digit symbol coding tasks and other cognitive measures in schizophrenia. Arch. Gen. Psychiatry 2007, 64(5):532-542.
14. Evans J.D., Heaton R.K., Paulsen J.S., Palmer B.W., Patterson T., Jeste D.V. The relationship of neuropsychological abilities to specific domains of functional capacity in older schizophrenia patients. Biol. Psychiatry 2003, 53(5):422-430.
15. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured Clinical Interview for DSM-IV Axis I Disorders - Clinical Version (SCID-CV) 1997, American Psychiatric Press, Washington, DC.
16. Gold J.M., Goldberg R.W., McNary S.W., Dixon L.B., Lehman A.F. Cognitive correlates of job tenure among patients with severe mental illness. Am. J. Psychiatry 2002, 159(8):1395-1402.
17. Golden C.J. Stroop Color and Word Test: a Manual for Clinical and Experimental Uses 1978, Stoelting Co., Chicago.
18. Hartman M., Steketee M.C., Silva S., Lanning K., McCann H. Working memory and schizophrenia: evidence for slowed encoding. Schizophr. Res. 2003, 59(2-3):99-113.
19. Harvey P.D., Keefe R.S., Patterson T.L., Heaton R.K., Bowie C.R. Abbreviated neuropsychological assessment in schizophrenia: prediction of different aspects of outcome. J. Clin. Exp. Neuropsychol. 2009, 31(4):462-471.
20. Heaton R.K., Chelune G.J., Talley J.L., Talley J.L., Kay G.G., Curtiss G. Wisconsin Card Sorting Test. Revised and Expanded 1993, Psychological Assessment Resources, Odessa, FL.
21. Holthausen E.A., Wiersma D., Sitskoorn M.M., Dingemans P.M., Schene A.H., van den Bosch R.J. Long-term memory deficits in schizophrenia: primary or secondary dysfunction?. Neuropsychology 2003, 17(4):539-547.
22. Jahshan C., Heaton R.K., Golshan S., Cadenhead K.S. Course of neurocognitive deficits in the prodrome and first episode of schizophrenia. Neuropsychology 2010, 24(1):109-120.
23. Jöreskog K.G., Sörbom D. LISREL 8.80 for Windows 2006, Scientific Software International, Inc, Lincolnwood, IL.
24. Kay S.R., Fiszbein A., Opler L.A. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr. Bull. 1987, 13(2):261-276.
25. Keefe R.S., Bilder R.M., Harvey P.D., Davis S.M., Palmer B.W., Gold J.M., Meltzer H.Y., Green M.F., Miller D.D., Canive J.M., Adler L.W., Manschreck T.C., Swartz M., Rosenheck R., Perkins D.O., Walker T.M., Stroup T.S., McEvoy J.P., Lieberman J.A. Baseline neurocognitive deficits in the CATIE schizophrenia trial. Neuropsychopharmacology 2006, 31(9):2033-2046.
26. McClure M.M., Bowie C.R., Patterson T.L., Heaton R.K., Weaver C., Anderson H., Harvey P.D. Correlations of functional capacity and neuropsychological performance in older patients with schizophrenia: evidence for specificity of relationships?. Schizophr. Res. 2007, 89(1-3):330-338.
27. McGurk S.R., Twamley E.W., Sitzer D.I., McHugo G.J., Mueser K.T. A meta-analysis of cognitive remediation in schizophrenia. Am. J. Psychiatry 2007, 164(12):1791-1802.
28. Mesholam-Gately R.I., Giuliano A.J., Goff K.P., Faraone S.V., Seidman L.J. Neurocognition in first-episode schizophrenia: a meta-analytic review. Neuropsychology 2009, 23(3):315-336.
29. Milev P., Ho B.C., Arndt S., Andreasen N.C. Predictive values of neurocognition and negative symptoms on functional outcome in schizophrenia: a longitudinal first-episode study with 7-year follow-up. Am. J. Psychiatry 2005, 162(3):495-506.
30. Niendam T.A., Bearden C.E., Zinberg J., Johnson J.K., O'Brien M., Cannon T.D. The course of neurocognition and social functioning in individuals at ultra high risk for psychosis. Schizophr. Bull. 2007, 33(3):772-781.
31. Nuechterlein K.H., Barch D.M., Gold J.M., Goldberg T.E., Green M.F., Heaton R.K. Identification of separable cognitive factors in schizophrenia. Schizophr. Res. 2004, 72(1):29-39.
32. Ojeda N., Pena J., Sanchez P., Elizagarate E., Ezcurra J. Processing speed mediates the relationship between verbal memory, verbal fluency, and functional outcome in chronic schizophrenia. Schizophr. Res. 2008, 101(1-3):225-233.
33. Ojeda N., Sanchez P., Pena J., Elizagarate E., Yoller A.B., Larumbe J., Gutierrez M., Casais L., Ezcurra J. Verbal fluency in schizophrenia: does cognitive performance reflect the same underlying mechanisms in patients and healthy controls?. J. Nerv. Ment. Dis. 2010, 198(4):286-291.
34. Osterrieth P.A. Le test de copie d'une figure complex: Contribution a l'etude de la perception et de la memoire [The Complex Figure Test: contribution to the study of perception and memory]. Arch. Psychol. 1944, 28:1021-1034.
35. Reitan R. Validity of the Trail Making Test as an indicator of organic brain damage. Percept. Mot. Skills 1985, 19:199-206.
36. Revheim N., Schechter I., Kim D., Silipo G., Allingham B., Butler P., Javitt D.C. Neurocognitive and symptom correlates of daily problem-solving skills in schizophrenia. Schizophr. Res. 2006, 83(2-3):237-245.
37. Rodriguez-Sanchez J.M., Crespo-Facorro B., Gonzalez-Blanch C., Perez-Iglesias R., Vazquez-Barquero J.L. Cognitive dysfunction in first-episode psychosis: the processing speed hypothesis. Br. J. Psychiatry Suppl. 2007, 51:s107-s110.
38. Salthouse T.A. Speed mediation of adult age differences in cognition. Dev. Psychol. 1993, 29(4):722-738.
39. Sanchez P., Ojeda N., Pena J., Elizagarate E., Yoller A.B., Gutierrez M., Ezcurra J. Predictors of longitudinal changes in schizophrenia: the role of processing speed. J. Clin. Psychiatry 2009, 70(6):888-896.
40. Schretlen D.J. Brief Test of Attention 1996, Psychological Assessment Resources, Odessa, FL.
41. Stirling J., White C., Lewis S., Hopkins R., Tantam D., Huddy A., Montague L. Neurocognitive function and outcome in first-episode schizophrenia: a 10-year follow-up of an epidemiological cohort. Schizophr. Res. 2003, 65(2-3):75-86.
42. Wang Q., Chan R., Sun J., Yao J., Deng W., Sun X., Liu X., Sham P.C., Ma X., Meng H., Murray R.M., Collier D.A., Li T. Reaction time of the Continuous Performance Test is an endophenotypic marker for schizophrenia: a study of first-episode neuroleptic-naive schizophrenia, their non-psychotic first-degree relatives and healthy population controls. Schizophr. Res. 2007, 89(1-3):293-298.
43. Wechsler D. The Wechsler Memory Scale-Revised 1987, Psychological Corporation, New York.
44. Wechsler D. WAIS-III Manual: Wechsler Adult Intelligence Scale-III 1997, Psychological Corporation, New York.