-
1
-
-
33846164111
-
Renal-cell carcinoma-molecular pathways and therapies
-
10.1056/NEJMe068263, 17215538
-
Brugarolas J. Renal-cell carcinoma-molecular pathways and therapies. N Engl J Med 2007, 356:185-187. 10.1056/NEJMe068263, 17215538.
-
(2007)
N Engl J Med
, vol.356
, pp. 185-187
-
-
Brugarolas, J.1
-
2
-
-
34347395733
-
Trastuzumab-mechanism of action and use in clinical practice
-
10.1056/NEJMra043186, 17611206
-
Hudis CA. Trastuzumab-mechanism of action and use in clinical practice. N Engl J Med 2007, 357:39-51. 10.1056/NEJMra043186, 17611206.
-
(2007)
N Engl J Med
, vol.357
, pp. 39-51
-
-
Hudis, C.A.1
-
3
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
10.1056/NEJMoa072113, 18160686
-
Miller K, Wang M, Gralow J, Dickler M, Cobleigh M, Perez EA, Shenkier T, Cella D, Davidson NE. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007, 357:2666-2676. 10.1056/NEJMoa072113, 18160686.
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
Dickler, M.4
Cobleigh, M.5
Perez, E.A.6
Shenkier, T.7
Cella, D.8
Davidson, N.E.9
-
4
-
-
22044453790
-
Erlotinib in lung cancer - molecular and clinical predictors of outcome
-
10.1056/NEJMoa050736, 16014883
-
Tsao MS, Sakurada A, Cutz JC, Zhu CQ, Kamel-Reid S, Squire J, Lorimer I, Zhang T, Liu N, Daneshmand M, et al. Erlotinib in lung cancer - molecular and clinical predictors of outcome. N Engl J Med 2005, 353:133-144. 10.1056/NEJMoa050736, 16014883.
-
(2005)
N Engl J Med
, vol.353
, pp. 133-144
-
-
Tsao, M.S.1
Sakurada, A.2
Cutz, J.C.3
Zhu, C.Q.4
Kamel-Reid, S.5
Squire, J.6
Lorimer, I.7
Zhang, T.8
Liu, N.9
Daneshmand, M.10
-
5
-
-
44249126754
-
Carcinoma of unknown primary with a colon-cancer profile-changing paradigm and emerging definitions
-
10.1016/S1470-2045(08)70151-7, 18510991
-
Varadhachary GR, Raber MN, Matamoros A, Abbruzzese JL. Carcinoma of unknown primary with a colon-cancer profile-changing paradigm and emerging definitions. Lancet Oncol 2008, 9:596-599. 10.1016/S1470-2045(08)70151-7, 18510991.
-
(2008)
Lancet Oncol
, vol.9
, pp. 596-599
-
-
Varadhachary, G.R.1
Raber, M.N.2
Matamoros, A.3
Abbruzzese, J.L.4
-
6
-
-
0029154961
-
Analysis of a diagnostic strategy for patients with suspected tumors of unknown origin
-
Abbruzzese JL, Abbruzzese MC, Lenzi R, Hess KR, Raber MN. Analysis of a diagnostic strategy for patients with suspected tumors of unknown origin. J Clin Oncol 1995, 13:2094-2103.
-
(1995)
J Clin Oncol
, vol.13
, pp. 2094-2103
-
-
Abbruzzese, J.L.1
Abbruzzese, M.C.2
Lenzi, R.3
Hess, K.R.4
Raber, M.N.5
-
7
-
-
76149112585
-
Determining tissue of origin for metastatic cancers: meta-analysis and literature review of immunohistochemistry performance
-
10.1097/PAI.0b013e3181a75e6d, 19550296
-
Anderson GG, Weiss LM. Determining tissue of origin for metastatic cancers: meta-analysis and literature review of immunohistochemistry performance. Appl Immunohistochem Mol Morphol 2010, 18:3-8. 10.1097/PAI.0b013e3181a75e6d, 19550296.
-
(2010)
Appl Immunohistochem Mol Morphol
, vol.18
, pp. 3-8
-
-
Anderson, G.G.1
Weiss, L.M.2
-
8
-
-
21044444707
-
Markers of adenocarcinoma characteristic of the site of origin: development of a diagnostic algorithm
-
10.1158/1078-0432.CCR-04-2236, 15897574
-
Dennis JL, Hvidsten TR, Wit EC, Komorowski J, Bell AK, Downie I, Mooney J, Verbeke C, Bellamy C, Keith WN, Oien KA. Markers of adenocarcinoma characteristic of the site of origin: development of a diagnostic algorithm. Clin Cancer Res 2005, 11:3766-3772. 10.1158/1078-0432.CCR-04-2236, 15897574.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3766-3772
-
-
Dennis, J.L.1
Hvidsten, T.R.2
Wit, E.C.3
Komorowski, J.4
Bell, A.K.5
Downie, I.6
Mooney, J.7
Verbeke, C.8
Bellamy, C.9
Keith, W.N.10
Oien, K.A.11
-
9
-
-
84866763589
-
Diagnostic work-up of carcinoma of unknown primary: from immunohistochemistry to molecular profiling
-
10.1093/annonc/mds357, 22987975
-
Oien KA, Dennis JL. Diagnostic work-up of carcinoma of unknown primary: from immunohistochemistry to molecular profiling. Ann Oncol 2012, 23(Suppl 10):x271-x277. 10.1093/annonc/mds357, 22987975.
-
(2012)
Ann Oncol
, vol.23
, Issue.SUPPL. 10
, pp. 10271-10277
-
-
Oien, K.A.1
Dennis, J.L.2
-
10
-
-
52449118245
-
Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary
-
10.1200/JCO.2007.14.6969, 18802156
-
Horlings HM, van Laar RK, Kerst JM, Helgason HH, Wesseling J, van der Hoeven JJ, Warmoes MO, Floore A, Witteveen A, Lahti-Domenici J, et al. Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary. J Clin Oncol 2008, 26:4435-4441. 10.1200/JCO.2007.14.6969, 18802156.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4435-4441
-
-
Horlings, H.M.1
van Laar, R.K.2
Kerst, J.M.3
Helgason, H.H.4
Wesseling, J.5
van der Hoeven, J.J.6
Warmoes, M.O.7
Floore, A.8
Witteveen, A.9
Lahti-Domenici, J.10
-
11
-
-
33645779944
-
Molecular classification of human cancers using a 92-gene real-time quantitative polymerase chain reaction assay
-
Ma XJ, Patel R, Wang X, Salunga R, Murage J, Desai R, Tuggle JT, Wang W, Chu S, Stecker K, et al. Molecular classification of human cancers using a 92-gene real-time quantitative polymerase chain reaction assay. Arch Pathol Lab Med 2006, 130:465-473.
-
(2006)
Arch Pathol Lab Med
, vol.130
, pp. 465-473
-
-
Ma, X.J.1
Patel, R.2
Wang, X.3
Salunga, R.4
Murage, J.5
Desai, R.6
Tuggle, J.T.7
Wang, W.8
Chu, S.9
Stecker, K.10
-
12
-
-
66349093950
-
Multicenter validation of a 1,550-gene expression profile for identification of tumor tissue of origin
-
10.1200/JCO.2008.17.9762, 19332734
-
Monzon FA, Lyons-Weiler M, Buturovic LJ, Rigl CT, Henner WD, Sciulli C, Dumur CI, Medeiros F, Anderson GG. Multicenter validation of a 1,550-gene expression profile for identification of tumor tissue of origin. J Clin Oncol 2009, 27:2503-2508. 10.1200/JCO.2008.17.9762, 19332734.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2503-2508
-
-
Monzon, F.A.1
Lyons-Weiler, M.2
Buturovic, L.J.3
Rigl, C.T.4
Henner, W.D.5
Sciulli, C.6
Dumur, C.I.7
Medeiros, F.8
Anderson, G.G.9
-
13
-
-
84862869591
-
A second-generation microRNA-based assay for diagnosing tumor tissue origin
-
10.1634/theoncologist.2011-0466, 3380879, 22618571
-
Meiri E, Mueller WC, Rosenwald S, Zepeniuk M, Klinke E, Edmonston TB, Werner M, Lass U, Barshack I, Feinmesser M, et al. A second-generation microRNA-based assay for diagnosing tumor tissue origin. Oncologist 2012, 17:801-812. 10.1634/theoncologist.2011-0466, 3380879, 22618571.
-
(2012)
Oncologist
, vol.17
, pp. 801-812
-
-
Meiri, E.1
Mueller, W.C.2
Rosenwald, S.3
Zepeniuk, M.4
Klinke, E.5
Edmonston, T.B.6
Werner, M.7
Lass, U.8
Barshack, I.9
Feinmesser, M.10
-
14
-
-
65349166324
-
Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma
-
10.1200/JCO.2008.19.4134, 19273703
-
Lebanony D, Benjamin H, Gilad S, Ezagouri M, Dov A, Ashkenazi K, Gefen N, Izraeli S, Rechavi G, Pass H, et al. Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma. J Clin Oncol 2009, 27:2030-2037. 10.1200/JCO.2008.19.4134, 19273703.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2030-2037
-
-
Lebanony, D.1
Benjamin, H.2
Gilad, S.3
Ezagouri, M.4
Dov, A.5
Ashkenazi, K.6
Gefen, N.7
Izraeli, S.8
Rechavi, G.9
Pass, H.10
-
15
-
-
66949150988
-
MiR-92b and miR-9/9* are specifically expressed in brain primary tumors and can be used to differentiate primary from metastatic brain tumors
-
10.1111/j.1750-3639.2008.00184.x, 2728890, 18624795
-
Nass D, Rosenwald S, Meiri E, Gilad S, Tabibian-Keissar H, Schlosberg A, Kuker H, Sion-Vardy N, Tobar A, Kharenko O, et al. MiR-92b and miR-9/9* are specifically expressed in brain primary tumors and can be used to differentiate primary from metastatic brain tumors. Brain Pathol 2009, 19:375-383. 10.1111/j.1750-3639.2008.00184.x, 2728890, 18624795.
-
(2009)
Brain Pathol
, vol.19
, pp. 375-383
-
-
Nass, D.1
Rosenwald, S.2
Meiri, E.3
Gilad, S.4
Tabibian-Keissar, H.5
Schlosberg, A.6
Kuker, H.7
Sion-Vardy, N.8
Tobar, A.9
Kharenko, O.10
-
16
-
-
43049180764
-
MicroRNA expression profiling of thyroid tumors: biological significance and diagnostic utility
-
10.1210/jc.2007-2696, 2386678, 18270258
-
Nikiforova MN, Tseng GC, Steward D, Diorio D, Nikiforov YE. MicroRNA expression profiling of thyroid tumors: biological significance and diagnostic utility. J Clin Endocrinol Metab 2008, 93:1600-1608. 10.1210/jc.2007-2696, 2386678, 18270258.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 1600-1608
-
-
Nikiforova, M.N.1
Tseng, G.C.2
Steward, D.3
Diorio, D.4
Nikiforov, Y.E.5
-
17
-
-
41849114566
-
MicroRNAs accurately identify cancer tissue origin
-
10.1038/nbt1392, 18362881
-
Rosenfeld N, Aharonov R, Meiri E, Rosenwald S, Spector Y, Zepeniuk M, Benjamin H, Shabes N, Tabak S, Levy A, et al. MicroRNAs accurately identify cancer tissue origin. Nat Biotechnol 2008, 26:462-469. 10.1038/nbt1392, 18362881.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 462-469
-
-
Rosenfeld, N.1
Aharonov, R.2
Meiri, E.3
Rosenwald, S.4
Spector, Y.5
Zepeniuk, M.6
Benjamin, H.7
Shabes, N.8
Tabak, S.9
Levy, A.10
-
18
-
-
52349083651
-
Serum microRNAs are promising novel biomarkers
-
10.1371/journal.pone.0003148, 2519789, 18773077
-
Gilad S, Meiri E, Yogev Y, Benjamin S, Lebanony D, Yerushalmi N, Benjamin H, Kushnir M, Cholakh H, Melamed N, et al. Serum microRNAs are promising novel biomarkers. PLoS One 2008, 3:e3148. 10.1371/journal.pone.0003148, 2519789, 18773077.
-
(2008)
PLoS One
, vol.3
-
-
Gilad, S.1
Meiri, E.2
Yogev, Y.3
Benjamin, S.4
Lebanony, D.5
Yerushalmi, N.6
Benjamin, H.7
Kushnir, M.8
Cholakh, H.9
Melamed, N.10
-
19
-
-
34447506198
-
Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells
-
10.1186/1472-6750-7-36, 1914054, 17603869
-
Li J, Smyth P, Flavin R, Cahill S, Denning K, Aherne S, Guenther SM, O'Leary JJ, Sheils O. Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells. BMC Biotechnol 2007, 7:36. 10.1186/1472-6750-7-36, 1914054, 17603869.
-
(2007)
BMC Biotechnol
, vol.7
, pp. 36
-
-
Li, J.1
Smyth, P.2
Flavin, R.3
Cahill, S.4
Denning, K.5
Aherne, S.6
Guenther, S.M.7
O'Leary, J.J.8
Sheils, O.9
-
20
-
-
67650252543
-
MicroRNA expression profiling outperforms mRNA expression profiling in formalin-fixed paraffin-embedded tissues
-
2713447, 19636399
-
Liu A, Tetzlaff MT, Vanbelle P, Elder D, Feldman M, Tobias JW, Sepulveda AR, Xu X. MicroRNA expression profiling outperforms mRNA expression profiling in formalin-fixed paraffin-embedded tissues. Int J Clin Exp Pathol 2009, 2:519-527. 2713447, 19636399.
-
(2009)
Int J Clin Exp Pathol
, vol.2
, pp. 519-527
-
-
Liu, A.1
Tetzlaff, M.T.2
Vanbelle, P.3
Elder, D.4
Feldman, M.5
Tobias, J.W.6
Sepulveda, A.R.7
Xu, X.8
-
21
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
10.1038/nature03702, 15944708
-
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, et al. MicroRNA expression profiles classify human cancers. Nature 2005, 435:834-838. 10.1038/nature03702, 15944708.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
-
22
-
-
80755141968
-
Performance and clinical evaluation of the 92-gene real-time PCR assay for tumor classification
-
10.1016/j.jmoldx.2011.04.004, 3157614, 21708287
-
Erlander MG, Ma XJ, Kesty NC, Bao L, Salunga R, Schnabel CA. Performance and clinical evaluation of the 92-gene real-time PCR assay for tumor classification. J Mol Diagn 2011, 13:493-503. 10.1016/j.jmoldx.2011.04.004, 3157614, 21708287.
-
(2011)
J Mol Diagn
, vol.13
, pp. 493-503
-
-
Erlander, M.G.1
Ma, X.J.2
Kesty, N.C.3
Bao, L.4
Salunga, R.5
Schnabel, C.A.6
-
23
-
-
77953139378
-
Validation of a microRNA-based qRT-PCR test for accurate identification of tumor tissue origin
-
10.1038/modpathol.2010.57, 20348879
-
Rosenwald S, Gilad S, Benjamin S, Lebanony D, Dromi N, Faerman A, Benjamin H, Tamir R, Ezagouri M, Goren E, et al. Validation of a microRNA-based qRT-PCR test for accurate identification of tumor tissue origin. Mod Pathol 2010, 23:814-823. 10.1038/modpathol.2010.57, 20348879.
-
(2010)
Mod Pathol
, vol.23
, pp. 814-823
-
-
Rosenwald, S.1
Gilad, S.2
Benjamin, S.3
Lebanony, D.4
Dromi, N.5
Faerman, A.6
Benjamin, H.7
Tamir, R.8
Ezagouri, M.9
Goren, E.10
-
24
-
-
42149135334
-
Gene expression profiling may improve diagnosis in patients with carcinoma of unknown primary
-
10.1038/sj.bjc.6604315, 2361712, 18414470
-
Bridgewater J, van Laar R, Floore A, Van TVL. Gene expression profiling may improve diagnosis in patients with carcinoma of unknown primary. Br J Cancer 2008, 98:1425-1430. 10.1038/sj.bjc.6604315, 2361712, 18414470.
-
(2008)
Br J Cancer
, vol.98
, pp. 1425-1430
-
-
Bridgewater, J.1
van Laar, R.2
Floore, A.3
Van, T.V.L.4
-
25
-
-
84878859633
-
Molecular Profiling Diagnosis in Unknown Primary Cancer: Accuracy and Ability to Complement Standard Pathology
-
10.1093/jnci/djt099, 23641043
-
Greco FA, Lennington WJ, Spigel DR, Hainsworth JD. Molecular Profiling Diagnosis in Unknown Primary Cancer: Accuracy and Ability to Complement Standard Pathology. J Natl Cancer Inst 2013, 105(11):782-790. 10.1093/jnci/djt099, 23641043.
-
(2013)
J Natl Cancer Inst
, vol.105
, Issue.11
, pp. 782-790
-
-
Greco, F.A.1
Lennington, W.J.2
Spigel, D.R.3
Hainsworth, J.D.4
-
26
-
-
77952607898
-
Molecular profiling in unknown primary cancer: accuracy of tissue of origin prediction
-
10.1634/theoncologist.2009-0328, 3227979, 20427384
-
Greco FA, Spigel DR, Yardley DA, Erlander MG, Ma XJ, Hainsworth JD. Molecular profiling in unknown primary cancer: accuracy of tissue of origin prediction. Oncologist 2010, 15:500-506. 10.1634/theoncologist.2009-0328, 3227979, 20427384.
-
(2010)
Oncologist
, vol.15
, pp. 500-506
-
-
Greco, F.A.1
Spigel, D.R.2
Yardley, D.A.3
Erlander, M.G.4
Ma, X.J.5
Hainsworth, J.D.6
-
27
-
-
79952609923
-
Accurate classification of metastatic brain tumors using a novel microRNA-based test
-
10.1634/theoncologist.2010-0305, 3228095, 21273512
-
Mueller WC, Spector Y, Edmonston TB, St Cyr B, Jaeger D, Lass U, Aharonov R, Rosenwald S, Chajut A. Accurate classification of metastatic brain tumors using a novel microRNA-based test. Oncologist 2011, 16:165-174. 10.1634/theoncologist.2010-0305, 3228095, 21273512.
-
(2011)
Oncologist
, vol.16
, pp. 165-174
-
-
Mueller, W.C.1
Spector, Y.2
Edmonston, T.B.3
St Cyr, B.4
Jaeger, D.5
Lass, U.6
Aharonov, R.7
Rosenwald, S.8
Chajut, A.9
-
28
-
-
79959224648
-
Prospective gene signature study using microRNA to identify the tissue of origin in patients with carcinoma of unknown primary
-
10.1158/1078-0432.CCR-10-2599, 21531815
-
Varadhachary GR, Spector Y, Abbruzzese JL, Rosenwald S, Wang H, Aharonov R, Carlson HR, Cohen D, Karanth S, Macinskas J, et al. Prospective gene signature study using microRNA to identify the tissue of origin in patients with carcinoma of unknown primary. Clin Cancer Res 2011, 17:4063-4070. 10.1158/1078-0432.CCR-10-2599, 21531815.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4063-4070
-
-
Varadhachary, G.R.1
Spector, Y.2
Abbruzzese, J.L.3
Rosenwald, S.4
Wang, H.5
Aharonov, R.6
Carlson, H.R.7
Cohen, D.8
Karanth, S.9
Macinskas, J.10
-
29
-
-
52449084470
-
Molecular profiling of carcinoma of unknown primary and correlation with clinical evaluation
-
10.1200/JCO.2007.14.4378, 18802157
-
Varadhachary GR, Talantov D, Raber MN, Meng C, Hess KR, Jatkoe T, Lenzi R, Spigel DR, Wang Y, Greco FA, et al. Molecular profiling of carcinoma of unknown primary and correlation with clinical evaluation. J Clin Oncol 2008, 26:4442-4448. 10.1200/JCO.2007.14.4378, 18802157.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4442-4448
-
-
Varadhachary, G.R.1
Talantov, D.2
Raber, M.N.3
Meng, C.4
Hess, K.R.5
Jatkoe, T.6
Lenzi, R.7
Spigel, D.R.8
Wang, Y.9
Greco, F.A.10
-
30
-
-
84865063456
-
Classification of the four main types of lung cancer using a microRNA-based diagnostic assay
-
10.1016/j.jmoldx.2012.03.004, 22749746
-
Gilad S, Lithwick-Yanai G, Barshack I, Benjamin S, Krivitsky I, Edmonston TB, Bibbo M, Thurm C, Horowitz L, Huang Y, et al. Classification of the four main types of lung cancer using a microRNA-based diagnostic assay. J Mol Diagn 2012, 14:510-517. 10.1016/j.jmoldx.2012.03.004, 22749746.
-
(2012)
J Mol Diagn
, vol.14
, pp. 510-517
-
-
Gilad, S.1
Lithwick-Yanai, G.2
Barshack, I.3
Benjamin, S.4
Krivitsky, I.5
Edmonston, T.B.6
Bibbo, M.7
Thurm, C.8
Horowitz, L.9
Huang, Y.10
-
31
-
-
84856339714
-
Cancer of unknown primary: progress in the search for improved and rapid diagnosis leading toward superior patient outcomes
-
10.1093/annonc/mdr306, 21709138
-
Greco FA, Oien K, Erlander M, Osborne R, Varadhachary G, Bridgewater J, Cohen D, Wasan H. Cancer of unknown primary: progress in the search for improved and rapid diagnosis leading toward superior patient outcomes. Ann Oncol 2012, 23:298-304. 10.1093/annonc/mdr306, 21709138.
-
(2012)
Ann Oncol
, vol.23
, pp. 298-304
-
-
Greco, F.A.1
Oien, K.2
Erlander, M.3
Osborne, R.4
Varadhachary, G.5
Bridgewater, J.6
Cohen, D.7
Wasan, H.8
-
32
-
-
84872567958
-
Molecular gene expression profiling to predict the tissue of origin and direct site-specific therapy in patients with carcinoma of unknown primary site: a prospective trial of the Sarah Cannon research institute
-
Hainsworth JD, Rubin MS, Spigel DR, Boccia RV, Raby S, Quinn R, Greco FA. Molecular gene expression profiling to predict the tissue of origin and direct site-specific therapy in patients with carcinoma of unknown primary site: a prospective trial of the Sarah Cannon research institute. J Clin Oncol 2012, 31:217-223.
-
(2012)
J Clin Oncol
, vol.31
, pp. 217-223
-
-
Hainsworth, J.D.1
Rubin, M.S.2
Spigel, D.R.3
Boccia, R.V.4
Raby, S.5
Quinn, R.6
Greco, F.A.7
|