Acetylcholinesterase and butyrylcholinesterase activities in obese Beagle dogs before and after weight loss

Veterinary Clinical Pathology

Volumn 42, Issue 2, 2013, Pages 207-211

  Tvarijonaviciute, Asta ^a   Ceron, Jose J ^a   Tecles, Fernando ^a  

^a UNIVERSITY OF MURCIA   (Spain)

Author keywords

Canine obesity; Cholesterol; Inflammation; Triglycerides

Indexed keywords

CANIS FAMILIARIS;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CHOLESTEROL; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; PHENOTHIAZINE DERIVATIVE; PROFENAMINE;

ANIMAL; BLOOD; DOG; DOG DISEASE; DRUG EFFECTS; ENZYMOLOGY; FEMALE; METABOLISM; OBESITY; PHYSIOLOGY; VETERINARY; WEIGHT REDUCTION;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ANIMALS; ANTICHOLESTEREMIC AGENTS; BUTYRYLCHOLINESTERASE; CHOLESTEROL; CHOLINESTERASE INHIBITORS; DOG DISEASES; DOGS; FEMALE; OBESITY; PHENOTHIAZINES; WEIGHT LOSS;

EID: 84878690216     PISSN: 02756382     EISSN: 1939165X     Source Type: Journal    
DOI: 10.1111/vcp.12032     Document Type: Article

References (29)

1. Markwell PJ, Butterwick RF. Obesity. In: Wills JM, ed. Waltham Book of Clinical Nutrition of the Dog and Cat. Tarrytown, NY: Pergamon Press (U.K.); 1994:131-148.
2. McGreevy PD, Thomson PC, Pride C, Fawcett A, Grassi T, Jones B. Prevalence of obesity in dogs examined by Australian veterinary practices and the risk factors involved. Vet Rec. 2005;156:695-707.
3. Burkholder WJ, Toll PW. Obesity. In: Hand MS, Thatcher CD, Reimillard RL, Roudebush P, Morris ML, Novotny BJ, eds. Small Animal Clinical Nutrition. 4th ed. Topeka, KS: Mark Morris Institute; 2000:401-430.
4. German AJ, Holden SL, Moxham GL, Holmes KL, Hackett RM, Rawlings JM. A simple, reliable tool for owners to assess the body condition of their dog or cat. J Nutr. 2006;136:2031S-2033S.
5. German AJ, Ryan VH, German AC, Wood IS, Trayhurn P. Obesity, its associated disorders and the role of inflammatory adipokines in companion animals. Vet J. 2010;185:4-9.
6. Massoulé J, Pezzementi L, Bom S, Krejci E, Vallette FM. Molecular and cellular biology of cholinesterase. Prog Neurobiol. 1993;41:31-41.
7. Boberg DR, Furtado-Alle L, Souza RL, Chautard-Freire-Maia EA. Molecular forms of butyrylcholinesterase and obesity. Genet Molec Biol. 2010;33:452-454.
8. Magarian EO, Dietz AJ. Correlation of cholinesterase with serum lipids and lipoproteins. J Clin Pharmacol. 1987;27:819-820.
9. Das UN. Acetylcholinesterase and butyrylcholinesterase as possible markers of low grade systemic inflammation. Medi Sci Monit. 2007;13:214-221.
10. Keller P. Enzyme activities in the dog: tissue analyses, plasma values, and intracellular distribution. Am J Vet Res. 1981;42:575-582.
11. Randell EW, Mathews MS, Zhang H, Seraj JS, Sun G. Relationship between serum butyrylcholinesterase and metabolic syndrome. Clin Biochem. 2005;38:799-805.
12. Calderon-Margalit R, Adler B, Abramson JH, Gofin J, Kark J. Butyrylcholinesterase activity, cardiovascular risk factors, and mortality in middle-aged and elderly men and woman in Jerusalem. Clin Chem. 2006;52:845-852.
13. Iwasaki T, Yoneda M, Nakajima A, Terauchi Y. Serum butyrylcholinesterase is strongly associated with adiposity, the serum lipid profile and insulin resistance. Intern Med. 2007;46:1633-1639.
14. Tvarijonaviciute A, Tecles F, Ceron JJ. Relationship between serum butyrylcholinesterase and obesity in dogs: A preliminary report. Vet J. 2010;186:197-200.
15. Tvarijonaviciute A, Tecles F, Martínez-Subiela S, Ceron JJ. Effect of weight loss on inflammatory biomarkers in obese dogs. Vet J. 2012;193:570-572.
16. Yamka RM, Friesen KG, Frantz NZ. Identification of canine markers related to obesity and the effects of weight loss on the markers of interest. Intern J Appl Res Vet Med. 2006;4:282-292.
17. Blanchard G, Nguyen P, Gayet C, Leriche I, Siliart B, Paragon BM. Rapid weight loss and a high-protein low-energy diet allows the recovery of ideal body composition and insulin sensitivity in obese dogs. J Nutr. 2004;134:2148S-2150S.
18. Son HR, d'Avingnon DA, Laflamme DP. Comparison of dual-energy x-ray absorptiometry and measurement of total body water content by deuterium oxide dilution for estimating body composition in dogs. Am J Vet Res. 1998;59:529-532.
19. Tecles F, Martinez-Subiela S, Bernal LJ, Ceron JJ. Use of whole blood for spectrophotometric determination of cholinesterase activity in dogs. Vet J. 2000;160:242-249.
20. Tecles F, Gutiérrez PC, Martínez SS, Cerón JJ. Effects of different variables on whole blood cholinesterase analysis in dogs. J Vet Diagn Invest. 2002;14(2):132-9.
21. Cerón JJ, Fernandes del Palacio, MJ, Bernal LJ, Gutierrez C. Automated spectrophotometric method using 2, 2′-dithiodipyridine acid for determination of cholinesterase in whole blood. J AOAC Internat. 1996;79:757-763.
22. Worek F, Mast U, Kiderlen D, Diepold C, Eyer P. Improved determination of acetylcholinesterase activity in human whole blood. Clin Chim Acta. 1999;288:73-90.
23. Naik RS, Doctor BP, Saxena A. Comparison of methods used for the determination of cholinesterase activity in whole blood. Chem Biol Interact. 2008;175:298-302.
24. Guidance for Industry: Bioanalytical Method Validation. US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, Center for Veterinary Medicine, 2001. Available at: www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM070107.pdf. Accessed February 11, 2013.
25. Dass P, Mejia M, Landes M, Jones R, Stuart B, Thyssen J. Cholinesterase: review of methods. Clin Chem. 1994;10:135-157.
26. Wilson BW, Padilla S, Henderson JD, et al. Factors in standardizing automated cholinesterase assays. J Toxicol Environ Health. 1996;48:187-195.
27. Cucuianu M, Nistor T, Hâncu N, Orbai P, Muscurel C, Stoian I. Serum cholinesterase activity correlates with serum insulin, C-peptide and free fatty acids levels in patients with type 2 diabetes. Rom J Intern Med. 2002;40:43-51.
28. Ryan VH, German AJ, Wood IS, Hunter L, Morris P, Trayhurn P. Adipokine expression and secretion by canine adipocytes: stimulation of inflammatory adipokine production by LPS and TNFalpha. Pflugers Arch. 2010;460:603-16.
29. Cazzola R, Rondanelli M, Russo-Volpe S, Ferrari E, Cestaro B. Decreased membrane fluidity and altered susceptibility to peroxidation and lipid composition in overweight and obese female erythrocytes. J Lipid Res. 2004;45:1846-1851.