BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

Translational Psychiatry

Volumn 3, Issue , 2013, Pages

  Quesseveur, G ^a   David, D J ^a   Gaillard, M C ^b,c   Pla, P ^c,d,e,f   Wu, M V ^g,h   Nguyen, H T ^a   Nicolas, V ^f   Auregan, G ^b,c   David, I ^a   Dranovsky, A ^g,h   Hantraye, P ^b,c   Hen, R ^g,h   Gardier, A M ^a   Deglon N ^b,c,i   Guiard, B P ^a  

^a University of Paris XI   (France)

^b INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^c CNRS   (France)

^d INSTITUT CURIE   (France)

^e INSERM U1005   (France)

^f UNIVERSITÉ PARIS SACLAY   (France)

^g Howard Hughes Medical Institute   (United States)

^h NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

ⁱ LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

antidepressant; astrocytes; brain derived neurotrophic factor; hippocampus; neurogenesis; selective serotonin reuptake inhibitors

Indexed keywords

ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; FLUOXETINE; MESSENGER RNA; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; N-(2-(4-(2-METHOXYPHENYL)-1-PIPERAZINYL)ETHYL)-N-(2-PYRIDINYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; N (2 (4 (2 METHOXYPHENYL) 1 PIPERAZINYL)ETHYL) N (2 PYRIDINYL)CYCLOHEXANECARBOXAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; ASTROCYTE; BRAIN DEPTH STIMULATION; BRAIN FUNCTION; CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEUROTRANSMISSION; NONHUMAN; PROTEIN EXPRESSION; ANIMAL; ANIMAL BEHAVIOR; ANXIETY; CHEMISTRY; DEPRESSION; DRUG EFFECTS; GENE EXPRESSION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; DRUG EFFECT;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; ANXIETY; ASTROCYTES; BEHAVIOR, ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSION; FLUOXETINE; GENE EXPRESSION; HIPPOCAMPUS; MALE; MICE; NEUROGENESIS; PIPERAZINES; PYRIDINES; SEROTONIN ANTAGONISTS; SEROTONIN RECEPTOR AGONISTS;

EID: 84878666533     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2013.30     Document Type: Article

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