Combustion derived ultrafine particles induce cytochrome P-450 expression in specific lung compartments in the developing neonatal and adult rat

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 10, 2013, Pages

  Chan, Jackie K W ^a   Vogel, Christoph F ^a   Baek, Jaeeun ^a   Kodani, Sean D ^a   Uppal, Ravi S ^a   Bein, Keith J ^a   Anderson, Donald S ^a   van Winkle, Laura S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aryl hydrocarbon receptor; Lung development; Particulate matter; Polycyclic aromatic hydrocarbons

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; MESSENGER RNA; POLYCYCLIC AROMATIC HYDROCARBON;

ARTICLE; BINDING AFFINITY; CELL MATURATION; CELL MEDIATED CYTOTOXICITY; CELL VIABILITY; COMBUSTION; IMMUNOLOCALIZATION; IN VITRO STUDY; IN VIVO STUDY; LUNG; LUNG DEVELOPMENT; LUNG PARENCHYMA; MALE; NEWBORN; NONHUMAN; POLLUTANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; UPREGULATION; XENOBIOTIC METABOLISM;

ARYL HYDROCARBON RECEPTOR; LUNG DEVELOPMENT; PARTICULATE MATTER; POLYCYCLIC AROMATIC HYDROCARBONS;

ANIMALS; ANIMALS, NEWBORN; ARYL HYDROCARBON HYDROXYLASES; CELLS, CULTURED; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; HUMANS; LUNG; MALE; PARTICULATE MATTER; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ARYL HYDROCARBON; SILICONES; U937 CELLS; UP-REGULATION;

EID: 84878664442     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00370.2012     Document Type: Article

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