A 914-bp promoter is sufficient to reproduce the endogenous prolyl oligopeptidase gene localization in the mouse placenta if not subject to position effect

Gene

Volumn 524, Issue 2, 2013, Pages 114-123

  Matsubara, Shin ^a   Maruyama, Yuki ^a   Kimura, Atsushi P ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

AP 2 ; Placenta; Position effect; Prolyl oligopeptidase; Promoter; Transgenic mouse

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; PROLYL ENDOPEPTIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DECIDUA; DNA METHYLATION; FEMALE; GENE ACTIVATION; GENE ACTIVITY; GENE DOSAGE; GENE EXPRESSION; GENE LOCATION; GENETIC REGULATION; IN VIVO STUDY; MOUSE; NONHUMAN; PLACENTA LOCALIZATION; POSITION EFFECT; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENE;

ANIMALS; BINDING SITES; DNA METHYLATION; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; FEMALE; GENE DOSAGE; GENE EXPRESSION REGULATION; GRANULOSA CELLS; GREEN FLUORESCENT PROTEINS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; PLACENTA; PREGNANCY; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; SERINE ENDOPEPTIDASES; TRANSCRIPTION FACTOR AP-2; TRANSCRIPTIONAL ACTIVATION; TRANSGENES;

MUS MUSCULUS;

EID: 84878650595     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.04.051     Document Type: Article

References (67)

1. Auman H.J., Nottoli T., Lakiza O., Winger Q., Donaldson S., Williams T. Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development. Development 2002, 129:2733-2747.
2. Bagheri-Fam S., et al. Long-range upstream and downstream enhancers control distinct subsets of the complex spatiotemporal Sox9 expression pattern. Dev. Biol. 2006, 291:382-397.
3. Boyer O., et al. Position-dependent variegation of a CD4 minigene with targeted expression to mature CD4+ T cells. J. Immunol. 1997, 159:3383-3390.
4. Brandt W., Khandekar M., Suzuki N., Yamamoto M., Lim K.C., Engel J.D. Defining the functional boundaries of the Gata2 locus by rescue with a linked bacterial artificial chromosome transgene. J. Biol. Chem. 2008, 283:8976-8983.
5. Breen G., et al. Two peptidase activities decrease in treated bipolar disorder not schizophrenic patients. Bipolar Disord. 2004, 6:156-161.
6. Bulger M., Groudine M. Functional and mechanistic diversity of distal transcription enhancers. Cell 2011, 144:327-339.
7. Eckert D., Buhl S., Weber S., Jäger R., Schorle H. The AP-2 family of transcription factors. Genome Biol. 2005, 6:246.
8. Frazar T.F., et al. Variegated expression from the murine band 3 (AE1) promoter in transgenic mice is associated with mRNA transcript initiation at upstream start sites and can be suppressed by the addition of the chicken beta-globin 5' HS4 insulator element. Mol. Cell. Biol. 2003, 23:4753-4763.
9. Frericks M., Esser C. A toolbox of novel murine house-keeping genes identified by meta-analysis of large scale gene expression profiles. Biochim. Biophys. Acta 2008, 1779:830-837.
10. García-Horsman J.A., Männistö P.T., Venäläinen J.I. On the role of prolyl oligopeptidase in health and disease. Neuropeptides 2007, 41:1-24.
11. Gaszner M., Felsenfeld G. Insulators: exploiting transcriptional and epigenetic mechanisms. Nat. Rev. Genet. 2006, 7:703-713.
12. Goossens F., De Meester I., Vanhoof G., Scharpé S. Distribution of prolyl oligopeptidase in human peripheral tissues and body fluids. Eur. J. Clin. Chem. Clin. Biochem. 1996, 34:17-22.
13. Goossens F., et al. Development and evaluation of peptide-based prolyl oligopeptidase inhibitors-introduction of N-benzyloxycarbonyl-prolyl-3-fluoropyrrolidine as a lead in inhibitor design. Eur. J. Biochem. 1997, 250:177-183.
14. Grosveld F., van Assendelft G.B., Greaves D.R., Kollias G. Position-independent, high-level expression of the human beta-globin gene in transgenic mice. Cell 1987, 51:975-985.
15. Hannula M.J., Männistö P.T., Myöhänen T.T. Sequential expression, activity and nuclear localization of prolyl oligopeptidase protein in the developing rat brain. Dev. Neurosci. 2011, 33:38-47.
16. Harraghy N., Regamey A., Girod P.A., Mermod N. Identification of a potent MAR element from the mouse genome and assessment of its activity in stable and transient transfections. J. Biotechnol. 2011, 154:11-20.
17. Heckert L.L., Sawadogo M., Daggett M.A., Chen J.K. The USF proteins regulate transcription of the follicle-stimulating hormone receptor but are insufficient for cell-specific expression. Mol. Endocrinol. 2000, 14:1836-1848.
18. Herbst F., et al. Extensive methylation of promoter sequences silences lentiviral transgene expression during stem cell differentiation in vivo. Mol. Ther. 2012, 20:1014-1021.
19. Higgs D.R. Do LCRs open chromatin domains?. Cell 1998, 95:299-302.
20. Illingworth R.S., Bird A.P. CpG islands-'a rough guide'. FEBS Lett. 2009, 583:1713-1720.
21. Jeong Y., El-Jaick K., Roessler E., Muenke M., Epstein D.J. A functional screen for sonic hedgehog regulatory elements across a 1Mb interval identifies long-range ventral forebrain enhancers. Development 2006, 133:761-772.
22. Jones B.K., Monks B.R., Liebhaber S.A., Cooke N.E. The human growth hormone gene is regulated by a multicomponent locus control region. Mol. Cell. Biol. 1995, 15:7010-7021.
23. Kamat A., Graves K.H., Smith M.E., Richardson J.A., Mendelson C.R. A 500-bp region, approximately 40kb upstream of the human CYP19 (aromatase) gene, mediates placenta-specific expression in transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:4575-4580.
24. Kellum R., Schedl P. A position-effect assay for boundaries of higher order chromosomal domains. Cell 1991, 64:941-950.
25. Kim T.H., et al. Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome. Cell 2007, 128:1231-1245.
26. Kimura A., Takahashi T. cDNA cloning of rat prolyl oligopeptidase and its expression in the ovary during the estrous cycle. J. Exp. Zool. 2000, 286:656-665.
27. Kimura A., Yoshida I., Takagi N., Takahashi T. Structure and localization of the mouse prolyl oligopeptidase gene. J. Biol. Chem. 1999, 274:24047-24053.
28. Kimura A., Matsui H., Takahashi T. Expression and localization of prolyl oligopeptidase in mouse testis and its possible involvement in sperm motility. Zoolog. Sci. 2002, 19:93-102.
29. Klüppel M., Beermann F., Ruppert S., Schmid E., Hummler E., Schütz G. The mouse tyrosinase promoter is sufficient for expression in melanocytes and in the pigmented epithelium of the retina. Proc. Natl. Acad. Sci. U. S. A. 1991, 88:3777-3781.
30. Li Q., Peterson K.R., Fang X., Stamatoyannopoulos G. Locus control regions. Blood 2002, 100:3077-3086.
31. Li Q., Zhang M., Han H., Rohde A., Stamatoyannopoulos G. Evidence that DNase I hypersensitive site 5 of the human beta-globin locus control region functions as a chromosomal insulator in transgenic mice. Nucleic Acids Res. 2002, 30:2484-2491.
32. Mantle D., Falkous G., Ishiura S., Blanchard P.J., Perry E.K. Comparison of proline endopeptidase activity in brain tissue from normal cases and cases with Alzheimer's disease, Lewy body dementia, Parkinson's disease and Huntington's disease. Clin. Chim. Acta 1996, 249:129-139.
33. Matsubara S., Takahashi T., Kimura A.P. Epigenetic patterns at the mouse prolyl oligopeptidase gene locus suggest the CpG island in the gene body to be a novel regulator for gene expression. Gene 2010, 465:17-29.
34. Matsubara S., Takahashi T., Kimura A.P. Localization and subcellular distribution of prolyl oligopeptidase in the mouse placenta. J. Mol. Histol. 2011, 42:251-264.
35. Mehta A.K., Majumdar S.S., Alam P., Gulati N., Brahmachari V. Epigenetic regulation of cytomegalovirus major immediate-early promoter activity in transgenic mice. Gene 2009, 428:20-24.
36. Mentlein R. Proline residues in the maturation and degradation of peptide hormones and neuropeptides. FEBS Lett. 1988, 234:251-256.
37. Miura N., Shibata S., Watanabe S. Z-321, a prolyl endopeptidase inhibitor, augments the potentiation of synaptic transmission in rat hippocampal slices. Behav. Brain Res. 1997, 83:213-216.
38. Myöhänen T.T., García-Horsman J.A., Tenorio-Laranga J., Männistö P.T. Issues about the physiological functions of prolyl oligopeptidase based on its discordant spatial association with substrates and inconsistencies among mRNA, protein levels, and enzymatic activity. J. Histochem. Cytochem. 2009, 57:831-848.
39. Nobrega M.A., Ovcharenko I., Afzal V., Rubin E.M. Scanning human gene deserts for long-range enhancers. Science 2003, 302:413.
40. Ohtsuki S., Homma K., Kurata S., Komano H., Natori S. A prolyl endopeptidase of Sarcophaga peregrina (flesh fly): its purification and suggestion for its participation in the differentiation of the imaginal discs. J. Biochem. 1994, 115:449-453.
41. Pedram M., Sprung C.N., Gao Q., Lo A.W., Reynolds G.E., Murnane J.P. Telomere position effect and silencing of transgenes near telomeres in the mouse. Mol. Cell. Biol. 2006, 26:1865-1878.
42. Perroud B., Alvarado R.J., Espinal G.M., Morado A.R., Phinney B.S., Warden C.H. In vivo multiplex quantitative analysis of 3 forms of alpha melanocyte stimulating hormone in pituitary of prolyl endopeptidase deficient mice. Mol. Brain 2009, 2:14.
43. Rao M.K., Wayne C.M., Meistrich M.L., Wilkinson M.F. Pem homeobox gene promoter sequences that direct transcription in a Sertoli cell-specific, stage-specific, and androgen-dependent manner in the testis in vivo. Mol. Endocrinol. 2003, 17:223-233.
44. Reddi P.P., Urekar C.J., Abhyankar M.M., Ranpura S.A. Role of an insulator in testis-specific gene transcription. Ann. N. Y. Acad. Sci. 2007, 1120:95-103.
45. Rennex D., Hemmings B.A., Hofsteenge J., Stone S.R. cDNA cloning of porcine brain prolyl endopeptidase and identification of the active-site seryl residue. Biochemistry 1991, 30:2195-2203.
46. Salers P. Evidence for the presence of prolyl oligopeptidase and its endogenous inhibitor in neonatal rat pancreatic beta-cells. Regul. Pept. 1994, 50:235-245.
47. Sapin V., Bouillet P., Oulad-Abdelghani M., Dastugue B., Chambon P., Dollé P. Differential expression of retinoic acid-inducible (Stra) genes during mouse placentation. Mech. Dev. 2000, 92:295-299.
48. Shewchuk B.M., Liebhaber S.A., Cooke N.E. Specification of unique Pit-1 activity in the hGH locus control region. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:11784-11789.
49. Shi D., Kellems R.E. Transcription factor AP-2gamma regulates murine adenosine deaminase gene expression during placental development. J. Biol. Chem. 1998, 273:27331-27338.
50. Shima Y., et al. Ventromedial hypothalamic nucleus-specific enhancer of Ad4BP/SF-1 gene. Mol. Endocrinol. 2005, 19:2812-2823.
51. Shima Y., et al. Pituitary homeobox 2 regulates adrenal4 binding protein/steroidogenic factor-1 gene transcription in the pituitary gonadotrope through interaction with the intronic enhancer. Mol. Endocrinol. 2008, 22:1633-1646.
52. Shirasawa Y., Osawa T., Hirashima A. Molecular cloning and characterization of prolyl endopeptidase from human T cells. J. Biochem. 1994, 115:724-729.
53. Shishido Y., et al. Effect of ZTTA, a prolyl endopeptidase inhibitor, on memory impairment in a passive avoidance test of rats with basal forebrain lesions. Pharm. Res. 1998, 15:1907-1910.
54. Szeltner Z., Polgár L. Structure, function and biological relevance of prolyl oligopeptidase. Curr. Protein Pept. Sci. 2008, 9:96-107.
55. Tan S.K., et al. AP-2γ regulates oestrogen receptor-mediated long-range chromatin interaction and gene transcription. EMBO J. 2011, 30:2569-2581.
56. Toide K., Okamiya K., Iwamoto Y., Kato T. Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on prolyl endopeptidase activity and substance P- and arginine-vasopressin-like immunoreactivity in the brains of aged rats. J. Neurochem. 1995, 65:234-240.
57. Warden C.H., Fisler J.S., Espinal G., Graham J., Havel P.J., Perroud B. Maternal influence of prolyl endopeptidase on fat mass of adult progeny. Int. J. Obes. 2009, 33:1013-1022.
58. Werling U., Schorle H. Transcription factor gene AP-2γ essential for early murine development. Mol. Cell. Biol. 2002, 22:3149-3156.
59. Wilk S. Prolyl endopeptidase. Life Sci. 1983, 33:2149-2157.
60. Williams R.S.B. Prolyl oligopeptidase and bipolar disorder. Clin. Neurosci. Res. 2004, 4:233-242.
61. Williams R.S., Eames M., Ryves W.J., Viggars J., Harwood A.J. Loss of a prolyl oligopeptidase confers resistance to lithium by elevation of inositol (1,4,5) trisphosphate. EMBO J. 1999, 18:2734-2745.
62. Yamakawa N., Shimeno H., Soeda S., Nagamatsu A. Regulation of prolyl oligopeptidase activity in regenerating rat liver. Biochim. Biophys. Acta 1994, 1199:279-284.
63. Yang J., Corces V.G. Chromatin insulators: a role in nuclear organization and gene expression. Adv. Cancer Res. 2011, 110:43-76.
64. Yoo E.J., et al. Tissue-specific chromatin modifications at a multigene locus generate asymmetric transcriptional interactions. Mol. Cell. Biol. 2006, 26:5569-5579.
65. Yoshida K., Inaba K., Ohtake H., Morisawa M. Purification and characterization of prolyl endopeptidase from the Pacific herring, Clupea pallasi, and its role in the activation of sperm motility. Dev. Growth Differ. 1999, 41:217-225.
66. Yoshimoto T., Tsukumo K., Takatsuka N., Tsuru D. An inhibitor for post-proline cleaving enzyme; distribution and partial purification from porcine pancreas. J. Pharmacobiodyn. 1982, 5:734-740.
67. Yoshimoto T., Kado K., Matsubara F., Koriyama N., Kaneto H., Tsuru D. Specific inhibitors for prolyl endopeptidase and their anti-amnesic effect. J. Pharmacobiodyn. 1987, 10:730-735.