Tissue-specific chromatin modifications at a multigene locus generate asymmetric transcriptional interactions

Molecular and Cellular Biology

Volumn 26, Issue 15, 2006, Pages 5569-5579

  Yoo, Eung Jae ^a   Cajiao, Isabela ^a,b   Kim, Jeong Seon ^a,c   Kimura, Atsushi P ^a,d   Zhang, Aiwen ^a,e   Cooke, Nancy E ^a   Liebhaber, Stephen A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

^d HOKKAIDO UNIVERSITY   (Japan)

^e OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD79B ANTIGEN; DEOXYRIBONUCLEASE I; GROWTH HORMONE; HUMAN GROWTH HORMONE; HUMAN GROWTH HORMONE N; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CELL SPECIFICITY; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; EUKARYOTE; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE LOCUS; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ORGANIZATION; GENETIC TRANSCRIPTION; GENOME; GENOMICS; HORMONAL REGULATION; HORMONE ACTION; HUMAN GENETICS; HYPOPHYSIS CELL; MAMMALIAN GENETICS; MOUSE; MULTIGENE FAMILY; NONHUMAN; PLACENTA; PRIORITY JOURNAL; PROTEIN ANALYSIS; REGULATORY SEQUENCE; RESTRICTION MAPPING; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD79; B-LYMPHOCYTES; CELL LINE; CHROMATIN; DEOXYRIBONUCLEASE I; GENE EXPRESSION REGULATION; HISTONES; HUMAN GROWTH HORMONE; HUMANS; LOCUS CONTROL REGION; MICE; MICE, TRANSGENIC; TRANSCRIPTION, GENETIC;

EUKARYOTA; MAMMALIA;

EID: 33746564603     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00405-06     Document Type: Article

References (30)

1. Baumeister, P., S. Luo, W. C. Skarnes, G. Sui, E. Sato, Y. Shi, and A. S. Lee. 2005. Endoplasmic reticulum stress induction of the Grp78/BiP promoter: activating mechanisms mediated by YY1 and its interactive chromatin modifiers. Mol. Cell. Biol. 25:4529-4540.
2. Bell, A. C., A. G. West, and G. Felsenfeld. 1997. The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell 98:387-396.
3. Bennani-Baiti, I. M., N. E. Cooke, and S. A. Liebhaber. 1998. Physical linkage of the human growth hormone gene cluster and the CD79b(Igβ/B29) gene. Genomics 48:258-264.
4. Benschop, R. J., and J. C. Cambier. 1999. B cell development: signal transduction by antigen receptors and their surrogates. Curr. Opin. Immunol. 11:143-151.
5. Cajiao, I., A. Zhang, E. J. Yoo, N. E. Cooke, and S. A. Liebhaber. 2004. Bystander gene activation by a locus control region. EMBO J. 23:3854-3863.
6. Chen, E. Y., Y.-C. Liao, D. H. Smith, H. A. Barrera-Saldana, R. E. Gelinas, and P. H. Seeburg. 1989. The human growth hormone locus: nucleotide sequence, biology, and evolution. Genomics 4:179-197.
7. Elefant, F., S. A. Liebhaber, and N. E. Cooke. 2000. Targeted recruitment and spreading of histone acetyltransferase activity by a locus control region. J. Biol. Chem. 275:13827-13834.
8. Elefant, F., Y. Su, S. A. Liebhaber, and N. E. Cooke. 2000. Patterns of histone acetylation suggest dual pathways for gene activation by a bifunctional locus control region. EMBO J. 19:6814-6822.
9. Eliassen, K. A., A. Baldwin, and E. M. Sikorski. 1998. Role for a YY1-binding element in replication-dependent mouse histone gene expression. Mol. Cell. Biol. 18:7105-7118.
10. Felsenfeld, G. 1996. Chromatin unfolds. Cell 86:13-19.
11. Felsenfeld, G., and M. Groudine. 2003. Controlling the double helix. Nature 421:448-453.
12. Gross, D. S., and W. T. Garrard. 1988. Nuclease hypersensitivity sites in chromatin. Annu. Rev. Biochem. 57:159-197.
13. Hebbes, T. R., A. L. Clayton, A. W. Thorne, and C. Crane-Robinson. 1994. Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken β-globin chromosomal domain. EMBO J. 13:1823-1830.
14. Hermanson, G. G., D. Eisenberg, P. W. Kincade, and R. Wall. 1988. B29: a member of the immunoglobulin gene superfamily exclusively expressed on B-lineage cells. Proc. Natl. Acad. Sci. USA 85:6890-6894.
15. Ho, Y., F. Elefant, N. Cooke, and S. Liebhaber. 2002. A denned locus control region determinant links chromatin domain acetylation with long-range gene activation. Mol. Cell 9:291-302.
16. International Human Genome Sequencing Consortium. 2004. Finishing the euchromatic sequence of the human genome. Nature 431:931-945.
17. Jones, B. K., B. R. Monks, S. A. Liebhaber, and N. E. Cooke. 1995. The human growth hormone gene is regulated by a multicomponent locus control region. Mol. Cell. Biol. 15:7010-7021.
18. Kim, J., S. Sif, B. Hones, A. Jackson, J. Loipally, E. Hiller, S. Winandy, A. Viel, A. Sawyer, T. Ikeda, R. Kingston, and K. Georgopoulos. 1999. ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity 10:345-355.
19. Kimura, A. P., S. A. Liebhaher, and N. E. Cooke. 2004. Epigenetic modifications at the human growth hormone locus predict distinct roles for histone acetylation and methylation in placental gene activation. Mol. Endocrinol. 18:1018-1032.
20. Lee, J. S., K. M. Galvin, and Y. Shi. 1993. Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1. Proc. Natl. Acad. Sci. USA 90:6145-6149.
21. Lewis, A., and A. Murrill. 2004. Genomic imprinting: CTCF protects the boundaries. Curr. Biol. 14:R284-R286.
22. MacLeod, J. N., A. K. Lee, S. A. Liebhaber, and N. E. Cooke. 1992. Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster. J. Biol. Chem. 267:14219-14226.
23. O'Neill, L. P., and B. M. Turner. 1996. immunoprecipitation of chromatin. Methods Enzymol. 274:189-197.
24. O'Niell, D. W., S. S. Schoetz, R. A. Lopez, M. Castle, L. Rabinoxitz, E. Shor, D. Krawchuk, M. G. Goll, M. Renz, H. Seelig, S. Han, R. H. Seong, S. D. Park, T. Agaiioti, N. Munshi, D. Thanos, G. Erdjument-Bromage, P. Tempst, and A. Bank. 2000. An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells. Mol. Cell. Biol. 20:7572-7582.
25. Patrone, L., S. E. Henson, R. Wall, and C. S. Malone. 2004. A conserved sequence upstream of the B29 (Igβ, CD79b) gene interacts with YY1. Mol. Biol. Rep. 31:1-11.
26. Sanchez, M., Z. Misulovin, A. L. Burkhardt, S. Mahajan, T. Costa, R. Franke, J. B. Bolen, and M. Nussenzweig. 1993. Signal transduction by immunoglobulin is mediated through igα and igβ. J. Exp. Med. 178:1049-1055.
27. Su, Y., S. A. Liebhaber, and N. E. Cooke. 2000. The human growth hormone gene cluster locus control region supports position-independent pituitary- and placenta-specific expression in the transgenic mouse. J. Biol. Chem. 275:7902-7909.
28. Thompson, A. A., W. J. Wood, M. J. Gilly, M. A. Damore, S. A. Omori, and R. Wall. 1996. The promoter and 5′-flanking sequences controlling human B29 gene expression. Blood 87:666-673.
29. Yang, C., L. H. Shapiro, M. Rivera, A. Kumar, and P. K. Brindle. 1998. A role for CREB binding protein and p300 transcriptional coactivators in Ets-1 transactivation functions. Mol. Cell. Biol. 18:2218-2229.
30. Yusufzai, T. M., and G. Felsenfeld. 2004. The 5′-HS4 chicken β-globin insulator is a CTCF-dependent nuclear matrix-associated element. Proc. Natl. Acad. Sci. USA 101:8620-8624.