Myofilament Ca2+ desensitization mediates positive lusitropic effect of neuronal nitric oxide synthase in left ventricular myocytes from murine hypertensive heart

Journal of Molecular and Cellular Cardiology

Volumn 60, Issue 1, 2013, Pages 107-115

  Jin, Chun Zi ^a,b   Jang, Ji Hyun ^a   Kim, Hae Jin ^a   Wang, Yue ^a   Hwang, In Chang ^a   Sadayappan, Sakthivel ^c   Park, Byung Mun ^d   Kim, Suhn Hee ^d   Jin, Zhe Hu ^b   Seo, Eun Yeong ^a   Kim, Kyung Hee ^a   Kim, Yong Jin ^a   Kim, Sung Joon ^a   Zhang, Yin Hua ^a,b  

^a Seoul National University   (South Korea)

^b Department of Cardiology   (China)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

^d Chonbuk National University Medical School   (South Korea)

Author keywords

Cardiac myosin binding protein C; Cardiac troponin I; Hypertension; Left ventricular myocyte; Myofilament Ca2+ sensitivity; NOS1; Relaxation

Indexed keywords

ANGIOTENSIN II; CALCIUM ION; MYOSIN BINDING PROTEIN C; NEURONAL NITRIC OXIDE SYNTHASE; PHOSPHOLAMBAN; SERINE; TROPONIN I; CALCIUM; NOS1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM DESENSITIZATION; CALCIUM METABOLISM; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; DIASTOLE; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HEART CONTRACTION; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART MUSCLE RELAXATION; HOMOGENATE; HYPERTENSION; MALE; MOUSE; MYOFILAMENT; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SARCOMERE; SYSTOLE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HEART MUSCLE; HEART VALVE; METABOLISM; MUSCLE FIBRIL; PATHOLOGY; RAT; SPRAGUE DAWLEY RAT;

MURINAE; RATTUS;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEART VALVES; HYPERTENSION; MICE; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOFIBRILS; NITRIC OXIDE SYNTHASE TYPE I; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84878650231     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.04.017     Document Type: Article

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