The 3.2 Å resolution structure of a receptor:CheA:CheW signaling complex defines overlapping binding sites and key residue interactions within bacterial chemosensory arrays

Biochemistry

Volumn 52, Issue 22, 2013, Pages 3852-3865

  Li, Xiaoxiao ^a   Fleetwood, Aaron D ^b,c   Bayas, Camille ^a   Bilwes, Alexandrine M ^a   Ortega, Davi R ^b,c   Falke, Joseph J ^d   Zhulin, Igor B ^b,c   Crane, Brian R ^a  

^a Department of Obstetrics Gynecology   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF TENNESSEE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINARY AND TERNARY COMPLEXES; CRYO-ELECTRON MICROSCOPY; HYDROPHOBIC RESIDUES; HYDROPHOBIC SURFACES; PROTEIN INTERACTION; RECEPTOR INTERACTION; RESOLUTION STRUCTURE; SEQUENCE COMPARISONS;

AMINO ACIDS; BINDING SITES; BIOINFORMATICS; CHEMICAL MODIFICATION; COMPLEX NETWORKS; CONTACTS (FLUID MECHANICS); ENZYMES; HYDROPHOBICITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERS; SURFACE CHEMISTRY;

PROTEINS;

ADAPTOR PROTEIN; BACTERIAL PROTEIN; CHEA KINASE REGULATORY MODULE; TETRAMER; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BINDING SITE; BIOINFORMATICS; CHEMICAL MODIFICATION; CHEMOTAXIS; COMPLEX FORMATION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ACTIVITY; HYDROPHOBICITY; MOLECULAR EVOLUTION; MOLECULAR INTERACTION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; SIGNAL TRANSDUCTION; THERMOTOGA MARITIMA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; COMPUTER SIMULATION; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; MEMBRANE PROTEINS; MODELS, MOLECULAR; PROTEIN ENGINEERING; PROTEIN KINASES; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; THERMOTOGA MARITIMA;

BACTERIA (MICROORGANISMS); THERMOTOGA MARITIMA; THERMOTOGAE; THERMOTOGAE (CLASS);

EID: 84878635193     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi400383e     Document Type: Article

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