Origins and diversification of a complex signal transduction system in prokaryotes

Science Signaling

Volumn 3, Issue 128, 2010, Pages

  Wuichet, Kristin ^a,b   Zhulin, Igor B ^a,b  

^a OAK RIDGE NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENETICS; BACTERIAL KINETICS; BACTERIUM TRANSDUCTION; CHEMOTAXIS; EVOLUTION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROKARYOTE; PROTEIN ANALYSIS; PROTEIN DOMAIN; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; BACTERIA; GENOMICS; METABOLISM; PHYLOGENY;

PROKARYOTA;

BACTERIA; BIOLOGICAL EVOLUTION; CHEMOTAXIS; GENOMICS; PHYLOGENY; SIGNAL TRANSDUCTION;

EID: 77956634301     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2000724     Document Type: Article

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87. Acknowledgments: We thank E. V. Koonin and J. S. Parkinson for comments on the manuscript and discussions and R. P. Alexander and L. E. Ulrich for technical assistance and discussions. Funding: This work was supported, in part, by NIH grant GM72285 (I.B.Z.) and by funds from the U.S. Department of Energy (DOE) BioEnergy Science Center, which is supported by the Office of Biological and Environmental Research in the DOE Office of Science. This research used resources of the National Center for Computational Sciences at Oak Ridge National Laboratory, which is supported by the Office of Science of the DOE under contract no. DE-AC05-00OR22725. Author contributions: K.W. collected sequence data and performed computational work; K.W. and I.B.Z. designed experiments, analyzed results, and wrote the paper. Competing interests: The authors declare that they have no competing interests.