Elevated ecto-5ê-nucleotidase-mediated increased renal adenosine signaling via a2b adenosine receptor contributes to chronic hypertension

Circulation Research

Volumn 112, Issue 11, 2013, Pages 1466-1478

  Zhang, Weiru ^a   Zhang, Yujin ^a   Wang, Wei ^a,b   Dai, Yingbo ^a   Ning, Chen ^a,b   Luo, Renna ^a,b   Sun, Kaiqi ^a,e   Glover, Louise ^d   Grenz, Almut ^d   Sun, Hong ^c   Tao, Lijian ^b   Zhang, Wenzheng ^a,b   Colgan, Sean P ^d   Blackburn, Michael R ^a,e   Eltzschig, Holger K ^d   Kellems, Rodney E ^a,e   Xia, Yang ^a,e  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b Departments of Nephrology   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF TEXAS   (United States)

Author keywords

adenosine; chronic renal disease; hypertension

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE A2B RECEPTOR; ANGIOTENSIN II; ECTO 5' NUCLEOTIDASE; ENDOTHELIN 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; ADENOSINE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; HIF1A PROTEIN, HUMAN; HIF1A PROTEIN, MOUSE; NT5E PROTEIN, HUMAN; NT5E PROTEIN, MOUSE; VASOCONSTRICTOR AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC KIDNEY DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERTENSION; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED DISORDER; CHRONIC DISEASE; CYTOLOGY; ENDOTHELIUM CELL; GENETICS; KIDNEY; METABOLISM; MIDDLE AGED; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; RENOVASCULAR HYPERTENSION;

ADENOSINE; CHRONIC RENAL DISEASE; HYPERTENSION;

5'-NUCLEOTIDASE; ADENOSINE; ADULT; ANGIOTENSIN II; ANIMALS; CELLS, CULTURED; CHRONIC DISEASE; ENDOTHELIAL CELLS; ENDOTHELIN-1; FEMALE; GENE EXPRESSION; GPI-LINKED PROTEINS; HUMANS; HYPERTENSION, RENAL; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KIDNEY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; RECEPTOR, ADENOSINE A2B; SIGNAL TRANSDUCTION; VASOCONSTRICTOR AGENTS;

MLCS; MLOWN;

EID: 84878627317     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.300166     Document Type: Article

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