Adenosine activates A2b receptors and enhances chloride secretion in kidney inner medullary collecting duct cells

Hypertension

Volumn 55, Issue 5, 2010, Pages 1123-1128

  Rajagopal, Madhumitha ^a   Pao, Alan C ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

A2b receptor; Adenosine; CFTR; Collecting duct; Renal medulla

Indexed keywords

ADENOSINE; ADENOSINE A2B RECEPTOR; CHLORIDE ION; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; SODIUM CHANNEL; SODIUM CHLORIDE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; CHLORIDE TRANSPORT; CONTROLLED STUDY; HYPERTENSION; KIDNEY COLLECTING TUBULE; KIDNEY TUBULE CELL; NATRIURESIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SODIUM INTAKE;

ADENOSINE; ANIMALS; CELL LINE; CHLORIDES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; KIDNEY MEDULLA; KIDNEY TUBULES, COLLECTING; PYRAZOLES; PYRIMIDINES; RATS; RECEPTOR, ADENOSINE A2B; TRIAZINES; TRIAZOLES; XANTHINES;

EID: 77951481402     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.109.143404     Document Type: Article

References (22)

1. Kizer NL, Vandorpe D, Lewis B, Bunting B, Russell J, Stanton BA. Vasopressin and cAMP stimulate electrogenic chloride secretion in an IMCD cell line. Am J Physiol. 1995;268:F854-F861.
2. Vandorpe D, Kizer N, Ciampollilo F, Moyer B, Karlson K, Guggino WB, Stanton BA. CFTR mediates electrogenic chloride secretion in mouse inner medullary collecting duct (mIMCD-K2) cells. Am J Physiol. 1995; 269:C683-C689.
3. Kizer NL, Lewis B, Stanton BA. Electrogenic sodium absorption and chloride secretion by an inner medullary collecting duct cell line (mIMCD-K2). Am J Physiol. 1995;268:F347-F355.
4. Vallon V, Muhlbauer B, Osswald H. Adenosine and kidney function. Physiol Rev. 2006;86:901-940. (Pubitemid 44033385)
5. Di Sole F. Adenosine and renal tubular function. Curr Opin Nephrol Hypertens. 2008;17:399-407.
6. Jackson EK, Mi Z, Zhu C, Dubey RK. Adenosine biosynthesis in the collecting duct. J Pharmacol Exp Ther. 2003;307:888-896. (Pubitemid 37494205)
7. Klinger M, Freissmuth M, Nanoff C. Adenosine receptors: G protein-mediated signalling and the role of accessory proteins. Cell Signal. 2002;14:99-108. (Pubitemid 34056581)
8. Yaar R, Jones MR, Chen JF, Ravid K. Animal models for the study of adenosine receptor function. J Cell Physiol. 2005;202:9-20. (Pubitemid 39603358)
9. Yagil Y. Interaction of adenosine with vasopressin in the inner medullary collecting duct. Am J Physiol. 1990;259:F679-F687. (Pubitemid 20359109)
10. Yagil Y. Differential effect of basolateral and apical adenosine on AVP-stimulated cAMP formation in primary culture of IMCD. Am J Physiol. 1992;263:F268-F276.
11. Moyer BD, McCoy DE, Lee B, Kizer N, Stanton BA. Adenosine inhibits arginine vasopressin-stimulated chloride secretion in a mouse IMCD cell line (mIMCD-K2). Am J Physiol. 1995;269:F884-F891. (Pubitemid 3020690)
12. Siragy HM, Linden J. Sodium intake markedly alters renal interstitial fluid adenosine. Hypertension. 1996;27:404-407. (Pubitemid 26083056)
13. Zou AP, Wu F, Li PL, Cowley AW Jr. Effect of chronic salt loading on adenosine metabolism and receptor expression in renal cortex and medulla in rats. Hypertension. 1999;33:511-516. (Pubitemid 29065712)
14. Wallace DP, Rome LA, Sullivan LP, Grantham JJ. cAMP-dependent fluid secretion in rat inner medullary collecting ducts. Am J Physiol Renal Physiol. 2001;280:F1019-F1029. (Pubitemid 32566462)
15. Rajagopal M, Fischer H, Widdicombe JH. Hormonal and purinergic stimulation of bicarbonate secretion in oviducts of rhesus monkey. Am J Physiol Endocrinol Metab. 2008;295:E55-E62.
16. Jacobson KA, Gao ZG. Adenosine receptors as therapeutic targets. Nat Rev Drug Discov. 2006;5:247-264.
17. Strohmeier GR, Reppert SM, Lencer WI, Madara JL. The A2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia. J Biol Chem. 1995;270:2387-2394.
18. Sitaraman SV, Wang L, Wong M, Bruewer M, Hobert M, Yun CH, Merlin D, Madara JL. The adenosine 2b receptor is recruited to the plasma membrane and associates with E3KARP and Ezrin upon agonist stimulation. J Biol Chem. 2002;277:33188-33195. (Pubitemid 34984837)
19. Wang L, Kolachala V, Walia B, Balasubramanian S, Hall RA, Merlin D, Sitaraman SV. Agonist-induced polarized trafficking and surface expression of the adenosine 2b receptor in intestinal epithelial cells: role of SNARE proteins. Am J Physiol Gastrointest Liver Physiol. 2004;287: G1100-G1107. (Pubitemid 39423703)
20. Barfuss DW, McCann WP, Katholi RE. Axial heterogeneity of adenosine transport and metabolism in the rabbit proximal tubule. Kidney Int. 1992;41:1143-1149.
21. Sonnenberg H. Secretion of salt and water into the medullary collecting duct of Ringer-infused rats. Am J Physiol. 1975;228:565-568.
22. Grantham JJ, Wallace DP. Return of the secretory kidney. Am J Physiol Renal Physiol. 2002;282:F1-F9.