Not so hot: Optimal housing temperatures for mice to mimic the thermal environment of humans

Molecular Metabolism

Volumn 2, Issue 1, 2013, Pages 5-9

  Speakman, John R ^a,b   Keijer, Jaap ^c  

^a INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Ambient temperature; Human; Lower critical temperature; Mouse; Thermoneutral; Thermoregulation

Indexed keywords

BASAL METABOLIC RATE; BED; BODY TEMPERATURE; BODY WEIGHT; CLOTHING; ENERGY EXPENDITURE; ENVIRONMENTAL TEMPERATURE; HOUSING TEMPERATURE; HUMAN; NESTING; NONHUMAN; PRIORITY JOURNAL; REVIEW; TEMPERATURE ACCLIMATIZATION; THERMAL EXPOSURE; THERMOREGULATION; WORK ENVIRONMENT;

EID: 84878622198     PISSN: 22128778     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmet.2012.10.002     Document Type: Review

References (54)

1. Benedict F.G., Fox E.L. Der Energieumsatz normaler und haarloser Mause bei verschiedener Umgebungstemperatur. Pflügers Archiv für die gesamte Physiologie 1933, 231:455.
2. Beynene, A.C., Gartner, K., and van Zutphen, L.F.M., 2001. Standardization of animal experimentation p. 103-110 in: Van Zutphen, L.F.M., Baumans, V., Beynene, A.C., (2001), Principles of laboratory animal Science, Second revised edition. Elsevier, Amsterdam, The Netherlands.
3. Black A.E., Coward W.A., Cole T.J., Prentice A.M. Human energy expenditure in affluent societies: an analysis of 574 doubly-labelled water studies. European Journal of Clinical Nutrition 1996, 50:72-92.
4. Cannon B., Nedergaard J. Thermogenesis challenges the adipostat hypothesis for body-weight control. Proceedings of the Nutrition Society 2009, 68:401-407.
5. Cannon B., Nedergaard J. Nonshivering thermogenesis and its adequate measurement in metabolic studies. Journal of Experimental Biology 2011, 214:242-253.
6. Chandler A.R., Messina M.M., Overton M.J. Thermoneutrality attenuates body weight gain in ovariectomised female mice. FASEB Journal 2007, 21:A460.
7. Code of practice for the housing of animals used in scientific procedures, HMSO, London, 1989 44pp.
8. Committee for the update of the guide for the care and use of laboratory animals, Institute for Laboratory Animal Research Guide for the care and use of laboratory animals (eighth ed.), National Research Council of the National Academies, The National Academies Press, Washington, DC. 2011. http://www.nap.edu.
9. DuBois E.F. Basal metabolism in health and disease 1936, Lea and Febiger, Philadelphia.
10. Enerbäck S., Jacobsson A., Simpson E.M., Guerra C., Yamashita H., Harper M.E., et al. Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese. Nature 1997, 387:90-94.
11. Even P.C., Nadkarni N.A. Indirect calorimetry in laboratory mice and rats: principles, practical considerations, interpretation and perspectives. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2012, 303:R459-R476.
12. Feldmann H.M., Golozoubova V., Cannon B., Nedergaard.J. UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metabolism 2009, 9:203-209.
13. Finn D.A., Bejanian M., Jones B.L., Syapin P.J., Alkana R.L. Temperature affects ethanol lethality in C57BL/6, 129, LS and SS mice. Pharmacology Biochemistry and Behavior 1989, 34:375-380.
14. Garami A., Pakai E., Oliveira D.L., Steiner A.A., Wanner S.P., Almeida M.C., et al. Thermoregulatory phenotype of the Trpv1 mouse: thermoeffector dysbalance with hyperkinesis. Journal of Neuroscience 2011, 31:1721-1733.
15. Garland H.O. Altered temperature. Variations in human physiology 1985, Manchester University Press, Manchester, UK, p. 111-33. R.M. Case, D.E. Evans (Eds.).
16. Gaskill B.N., Rohr S.A., Pajor E.A., Lucas J.R., Garner J.P. Some like it hot: mouse temperature preferences in laboratory housing. Applied Animal Behaviour Science 2009, 116:279-285.
17. Golozoubova V., Gullberg H., Matthias A., Cannon B., Vennström B., Nedergaard J. Depressed thermogenesis but competent brown adipose tissue recruitment in mice devoid of all hormone-binding thyroid hormone receptors. Molecular Endocrinology 2004, 18:384-401.
18. Gordon C.J. Temperature regulation of laboratory rodents 1993, Cambridge University Press, Cambridge, UK.
19. Gordon C.J., Becker P., Ali J.S. Behavioral thermoregulatory responses of single- and group-housed mice. Physiology & Behavior 1998, 65:255-262.
20. Gordon C.J. Effect of cage bedding on temperature regulation and metabolism of group-housed female mice. Comparative Medicine 2004, 54:51-56.
21. Hardy J.D., Dubois E.F. Differences between men and women in their response to cold. Proceedings of the National Academy of Sciences of the United States of America 1937, 26:389-398.
22. Havenaar, R., Meijer, J.C., Morton, D.B., Ritskes_Hoitinga, J., and Zwart, P., 2001. Biology and husbandry of laboratory animals. In: Van Zutphen LFM, Baumans V, Beynene AC (Eds.), Principles of laboratory animal Science, 2nd revised edition. Elsevier, Amsterdam, The Netherlands, 2001. p. 19-76.
23. Hayes J.P., Speakman J.R., Racey P.A. The contributions of local heating and reducing exposed surface-area to the energetic benefits of huddling by short-tailed field voles (Microtus-agrestis). Physiological Zoology 1992, 65:742-762.
24. Herrington L.P. The heat regulation of small laboratory animals at various environmental temperatures. American Journal of Physiology 1940, 129:123-139.
25. 2 consumption; opposite effects of leptin and etomoxir on respiratory quotient in mice. Obesity 2006, 14:673-682.
26. Hussein H.K. Effect of temperature and body size on the metabolic rate of Egyptian house mice (Mus musculus) and the roof rat (Rattus rattus). Journal of the Islamic Academy of Sciences 1991, 4:249-252.
27. Karp C.L. Unstressing intemperate models: how cold stress undermines mouse modelling. Journal of Experimental Medicine 2012, 209:1069-1074.
28. Kingma B., Frijns A., van Marken Lichtenbelt W. The thermoneutral zone: implications for metabolic studies. Frontiers in Bioscience 2012, e4.
29. Klaus S., Münzberg H., Trüloff C., Heldmaier G. Physiology of transgenic mice with brown fat ablation: obesity is due to lowered body temperature. American Journal of Physiology 1998, 274:R287-R293.
30. Liu X.T., Rossmeisl M., McClaine J., Kozak L.P. Paradoxical resistance to diet-induced obesity in UCP-1 deficient mice. Journal of Clinical Investigation 2003, 111:399-407.
31. Lodhi I.J., Semenkovich C.F. Why we should put clothes on mice. Cell Metabolism 2009, 9:111-112.
32. Malcolm R.D., Alkana R.L. Temperature dependence of ethanol lethality in mice. Journal of Pharmacy and Pharmacology 1983, 35:306-311.
33. Manning-Geist B. Oral rapamycin does not mimic caloric restriction in mice. Unpublished thesis. Willamsburg College. Supervisor Swoap S, 2011. (accessed online).
34. Meyer C.W., Klingenspor M., Rozman J., Heldmaier G. Gene or size: metabolic rate and body temperature in obese growth hormone-deficient dwarf mice. Obesity Research 2004, 12:1509-1518.
35. Mount L.E. Metabolic rate and thermal insulation in albino and hairless mice. Journal of Physiology 1971, 217:315-326.
36. Overton J.M. Phenotyping small animals as models for the human metabolic syndrome: thermoneutrality matters. International Journal of Obesity 2010, 34:S53-S58.
37. 9-tetrahydrocannabinol on the rates of oxygen consumption of mice. British Journal of Pharmacology 1977, 60:559-568.
38. Rintamäki H. Human responses to cold. Alaska Medicine 2007, 49(Suppl. 2):29-31.
39. Romanovsky A.A., Ivanov A.I., Shimansky Y.P. Molecular biology of thermoregulation. Selected contribution: ambient temperature for experiments in rats: a new method for determining the zone of thermal neutrality. Journal of Applied Physiology 2002, 92:2667-2679.
40. Scholander P.F., Hock R., Walters V., Johnson F., Irving L. Heat regulation in some arctic and tropical mammals and birds. Biological Bulletin 1950, 99:237-258.
41. Scholander P.F., Lange Andersen K., Krog J., Vogt Lorentzen F., Steen J. Critical temperature in Lapps. Journal of Applied Physiology 1957, 10:231-234.
42. Selman C., Lumsden S., Korhonen T., Bunger L., Hill W.G., Speakman J.R. Thermoregulatory responses of two mouse Mus musculus strains selectively bred for high and low food intake. Journal of Comparative Physiology B 2001, 171:661-668.
43. Speakman, JR. Measuring energy metabolism in the mouse-theoretical, practical and analytical considerations. Frontiers in Physiology, (in press).
44. Speakman J.R., Krol E. Limits to sustained energy intake IX: a review of hypotheses. Journal of Comparative Physiology B 2005, 175:375-394.
45. Speakman J.R., Rossi F.P. No support for socio-physiological suppression effect on metabolism of paired white mice (Mus sp.). Functional Ecology 1999, 13:373-382.
46. Speakman J.R., Westerterp K.R. Associations between energy demands, physical activity and body composition in adult humans between 18 and 96 years of age. American Journal of Clinical Nutrition 2010, 92:826-834.
47. Swoap S.J., Li C., Wess J., Parsons A.D., Williams T.D., Overton J.M. Vagal tone dominates autonomic control of mouse heart rate at thermoneutrality. American Journal of Physiology Heart and Circulatory Physiology 2008, 294:H1581-H1588.
48. Terroine E.F., Trautmann S. Influence de la temperature exterieure sur la production calorique des homeothermes et loi des surfaces. Annales de Physiologie et de Physicochimie Biologique 1927, 3:422.
49. Tschöp M.H., Speakman J.R., Arch J.R.S., Auwerx J., Brüning J.C., Chan L., et al. A guide to analysis of mouse energy metabolism. Nature Methods 2012, 9:57-63.
50. Vaz M., Karaolis N., Draper A., Shetty P. A compilation of energy costs of physical activities. Public Health Nutrition 2005, 8:1153-1183.
51. Winslow CEA., Herrington LP. Temperature and human life 1949, Princeton University press, Princeton.
52. Witte M.M., Reshuehr D., Chandler A.R., Mehle A.K., Overton J.M. Female mice and rats exhibit species specific metabolic and behavioural responses to ovariectomy. General and Comparative Endocrinology 2010, 166(S1):520-528.
53. Yamauchi C., Fujita S., Obara T., Ueda T. Effects of room temperature on reproduction, body and organ weights, food and water intakes, and hematology in mice. Experimental Animals 1983, 32:1-11.
54. Clo - Clothing and Thermal Insulation. Online. 2012. Available from URL: l. http://www.engineeringtoolbox.com/clo-clothing-thermal-insulation-d_732.htm.