Apoptosis of human gastric cancer cells line SGC 7901 induced by garlic-derived compound S-allylmercaptocysteine (SAMC)

European Review for Medical and Pharmacological Sciences

Volumn 17, Issue 6, 2013, Pages 745-751

  Yan, J Y ^a   Tian, F M ^b   Hu, W N ^a   Zhang, J H ^a   Cai, H F ^a   Li, N ^a  

^a TANGSHAN PEOPLE S HOSPITAL   (China)

^b HEBEI UNITED UNIVERSITY   (China)

Author keywords

Garlic; JNK and P38 pathway; SAMC; SGC 7901

Indexed keywords

GARLIC EXTRACT; JANUS KINASE; S ALLYLMERCAPTOCYSTEINE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GARLIC; GROWTH INHIBITION; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PROTEIN DETERMINATION; STOMACH CANCER;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CYSTEINE; GARLIC; HUMANS; MAP KINASE SIGNALING SYSTEM; STOMACH NEOPLASMS;

EID: 84878619425     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. HOHENBERGER P, GRETSCHEL S. Gastric cancer. Lancet 2003; 362(9380): 305-315.
2. LEUNG WK, WU MS, KAKUGAWA Y, KIM JJ, YEOH KG, GOH KL, WU KC, WU DC, SOLLANO J, KACHINTORN U, GOTODA T, LIN JT, YOU WC, NG EK, SUNG JJ; ASIA PACIFIC WORKING GROUP ON GASTRIC CANCEr. Screening for gastric cancer in Asia: current evidence and practice. Lancet Oncol 2008; 9: 279-287.
3. ZHANG W, HA M, GONG Y, XU Y, DONG N, YUAN Y. Allicin induces apoptosis in gastric cancer cells through activation of both extrinsic and intrinsic pathways. Oncol Rep 2010; 24: 1585-1592.
4. DOREY K, BARILA D, GAVIN AC, NEBREDA AR, SUPERTIFURGA G. Regulation of human c-Abl tyrosine kinase activity in Xenopus oocytes and acceleration of progesterone-induced G2/M transition by oncogenic forms. Biol Chem 1999; 380: 223-230.
5. RAHMAN K, LOWE GM. Garlic and cardiovascular disease: a critical review. J Nutr 2006; 136(3 Suppl): 736S-740S.
6. SODIMU O, JOSEPH PK, AUGUSTI KT. Certain biochemical effects of garlic oil on rats maintained on high fat-high cholesterol diet. Experientia 1984; 40: 78-80.
7. LEE Y. Induction of apoptosis by S-allylmercapto-Lcysteine, a biotransformed garlic derivative, on a human gastric cancer cell line. Int J Mol Med 2008; 21: 765-770.
8. HO YS, WU CH, CHOU HM, WANG YJ, TSENG H, CHEN CH, CHEN LC, LEE CH, LIN SY. Molecular mechanisms of econazole-induced toxicity on human colon cancer cells: G0/G1 cell cycle arrest and caspase 8-independent apoptotic signaling pathways. Food Chem Toxicol 2005; 43: 1483-1495.
9. CHOMCZYNSKI P, SACCHI N. Single-step method of RNA isolation by acid guanidinium thiocyanatephenol- chloroform extraction. Anal Biochem 1987; 162: 156-159.
10. O'DRISCOLL L, DALY C, SALEH M, CLYNES M. The use of reverse transcriptase-polymerase chain reaction (RT-PCR) to investigate specific gene expression in multidrug-resistant cells. Cytotechnology 1993; 12: 289-314.
11. SAIKI RK, GELFAND DH, STOFFEL S, SCHARF SJ, HIGUCHI R, HORN GT, MULLIS KB, ERLICH HA. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 1988; 239(4839): 487-491.
12. PINTO JT, LAPSIA S, SHAH A, SANTIAGO H, KIM G. Antiproliferative effects of garlic-derived and other allium related compounds. Adv Exp Med Biol 2001; 492: 83-106.
13. HSING AW, CHOKKALINGAM AP, GAO YT, MADIGAN MP, DENG J, GRIDLEY G, FRAUMENI JF JR. Allium vegetables and risk of prostate cancer: a populationbased study. J Natl Cancer Inst 2002; 94: 1648-1651.
14. WAGNER EF, NEBREDA AR. Signal integration by JNK and p38 MAPK pathways in cancer development. Nat Rev Cancer 2009; 9: 537-549.
15. NEBREDA AR, PORRAS A. p38 MAP kinases: beyond the stress response. Trends Biochem Sci 2000; 25: 257-260.
16. KYRIAKIS JM, AVRUCH J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 2001; 81: 807-869.
17. WESTON CR, DAVIS RJ. The JNK signal transduction pathway. Curr Opin Genet Dev 2002; 12: 14-21.
18. RINCON M, DAVIS RJ. Regulation of the immune response by stress-activated protein kinases. Immunol Rev 2009; 228: 212-24.
19. XIAO D, PINTO JT, SOH JW, DEGUCHI A, GUNDERSEN GG, PALAZZO AF, YOON JT, SHIRIN H, WEINSTEIN IB. Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation. Cancer Res2003; 63: 6825-6837.
20. WESTON CR, DAVIS RJ. The JNK signal transduction pathway. Curr Opin Cell Biol 2007; 19: 142-149.
21. TOURNIER C, HESS P, YANG DD, XU J, TURNER TK, NIMNUAL A, BAR-SAGI D, JONES SN, FLAVELL RA, DAVIS RJ. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 2000; 288(5467): 870-874.
22. AMBROSINO C, NEBREDA AR. Cell cycle regulation by p38 MAP kinases. Biol Cell 2001; 93: 47-51.
23. WANG X, MCGOWAN CH, ZHAO M, HE L, DOWNEY JS, FEARNS C, WANG Y, HUANG S, HAN J. Involvement of the MKK6-p38gamma cascade in gamma-radiation- induced cell cycle arrest. Mol Cell Biol 2000; 20: 4543-4552.