Thyrotropin-releasing hormone receptor type 1 (TRH-R1), not TRH-R2, primarily mediates taltirelin actions in the CNS of mice

Neuropsychopharmacology

Volumn 38, Issue 6, 2013, Pages 950-956

  Thirunarayanan, Nanthakumar ^a   Nir, Eshel A ^a   Raaka, Bruce M ^a   Gershengorn, Marvin C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

CNS effects; taltirelin; thyrotropin releasing hormone (TRH); TRH analogs; TRH receptors

Indexed keywords

HORMONE RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE; KETAMINE; PENTOBARBITAL; PROTIRELIN RECEPTOR TYPE 1; PROTIRELIN RECEPTOR TYPE 2; TALTIRELIN; UNCLASSIFIED DRUG; XYLAZINE;

ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; AROUSAL; ARTICLE; BINDING ASSAY; BINDING COMPETITION; BRAIN MEMBRANE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CENTRAL NERVOUS SYSTEM; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG BINDING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LATENT PERIOD; MOUSE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RIGHTING REFLEX; SEDATION; SLEEP TIME; TAIL FLICK TEST; TREMOR;

ANIMALS; CENTRAL NERVOUS SYSTEM; HEK293 CELLS; HUMANS; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; PROTEIN BINDING; RECEPTORS, THYROTROPIN-RELEASING HORMONE; THYROTROPIN-RELEASING HORMONE;

EID: 84878617543     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.256     Document Type: Article

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