Diversity of thyrotropin-releasing hormone receptors in the pituitary and discrete brain regions of rats

Japanese Journal of Pharmacology

Volumn 79, Issue 3, 1999, Pages 313-317

  Asai, Hidetoshi ^a   Kinoshita, Kiyoshi ^a   Yamamura, Michio ^a   Matsuoka, Yuzo ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Brain region; Pituitary; Receptor binding; Taltirelin (TA 0910, TRH analog); TRH (thyrotropin releasing hormone)

Indexed keywords

GUANOSINE TRIPHOSPHATE; GUANYLYLIMIDODIPHOSPHATE; PROTIRELIN; PROTIRELIN RECEPTOR; TALTIRELIN;

ADENOHYPOPHYSIS; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN CORTEX; BRAIN REGION; BRAIN STEM; CEREBELLUM; CONTROLLED STUDY; HYPOPHYSIS; HYPOTHALAMUS; MALE; NONHUMAN; RAT;

EID: 0032897435     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.79.313     Document Type: Article

References (21)

1. Hinkle PM: Pituitary TRH receptors. Ann NY Acad Sci 553, 176-187 (1989)
2. Sharif NA: Quantitative autoradiography of TRH receptors in discrete brain regions of different mammalian species. Ann NY Acad Sci 553, 147-175 (1989)
3. Griffiths EC: Thyrotropin-releasing hormone: Endocrine and central effects. Psychoneuroendocrinology 10, 225-235 (1985)
4. Horita A, Carino MA and Lai H: Pharmacology of thyrotropin-releasing hormone. Annu Rev Pharmacol Toxicol 26, 311-332 (1986)
5. Sharif NA, To ZP and Whiting RL: Analogs of thyrotropin-releasing hormone (TRH): Receptor affinities in brains, spinal cords, and pituitaries of different species. Neurochem Res 16, 95-103 (1991)
6. 2-TRH: binding to TRH receptors in rat brain homogenates. Eur J Pharmacol 180, 1-12 (1990)
7. Funatsu K, Teshima S and Inanaga K: Various types of thyrotropin-releasing hormone receptors in discrete brain regions and the pituitary of the rat. J Neurochem 45, 390-397 (1985)
8. Suzuki M, Sugano H, Matsumoto K, Yamamura M and Ishida R: Synthesis and central nervous system actions of thyrotropin-releasing hormone analogues containing a dihydroorotic acid moiety. J Med Chem 33, 2130-2137 (1990)
9. Yamamura M, Kinoshita K, Nakagawa H and Ishida R: Pharmacological study of TA-0910, a new thyrotropin-releasing hormone (TRH) analog (2): Involvement of the DA system in locomotor stimulating action of TA-0910. Jpn J Pharmacol 55, 57-68 (1991)
10. Yamamura M, Kinoshita K, Nakagawa H and Ishida R: Pharmacological study of TA-0910, a new thyrotropin-releasing hormone (TRH) analog (3): Inhibition of pentobarbital anesthesia. Jpn J Pharmacol 55, 69-80 (1991)
11. Gershengorn MC and Osman R: Molecular and cellular biology of thyrotropin-releasing hormone receptors. Physiol Rev 76, 175-191 (1996)
12. Hoffman BB, Mullikin-Kilpatrick D and Lefkowitz RJ: Heterogeneity of radioligand binding to α-adrenergic receptors. J Biol Chem 255, 4645-4652 (1980)
13. Kent RS, Lean AD and Lefkowitz RJ: A quantitative analysis of beta-adrenergic receptor interactions: Resolution of high and low affinity states of the receptor by computer modeling of ligand binding data. Mol Pharmacol 17, 14-23 (1980)
14. Ogawa N, Yamawaki Y, Kuroda H, Nukina I, Ota Z, Fujino M and Yanaihara N: Characteristics of thyrotropin releasing hormone (TRH) receptors in rat brain. Peptides 3, 669-677 (1982)
15. Lowry OH, Rosebrough NJ, Farr AL and Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 193, 265-275 (1951)
16. Yamaoka K, Tanigawara Y, Nakagawa T and Uno T: A pharmacokinetic analysis program (multi) for microcomputer. J Pharmacobiodyn 4, 879-885 (1981)
17. Burt DR and Taylor RL: Guanine nucleotides modulate receptor binding for TRH in pituitary but not CNS. Soc Neurosci Abstr 6, 255 (1980)
18. Taylor RL and Burt DR: Guanine nucleotides modulate TRH-receptor binding in sheep anterior pituitary. Mol Cell Endocrinol 21, 85-91 (1981)
19. Johnson WA, Nathanson NM and Horita A: Receptor binding and characterization of TRH receptors. Ann NY Acad Sci 553, 137-146 (1989)
20. Iriuchijima T and Mori M: Regional dissociation of cyclic AMP and inositol phosphate formation in response to thyrotropin-releasing hormone in the rat brain. J Neurochem 52, 1944-1946 (1989)
21. Kodama H, Fukushima T, Chishima S, Sugihara J and Yoshikawa M: Disposition of taltirelin (3): The transfer into the brain and brain distribution in rats. Xenobio Metabol Dispos 12, 483-490 (1997)