메뉴 건너뛰기




Volumn 73, Issue 11, 2013, Pages 3316-3325

Inhibition of tumor cell migration by LD22-4, an N-terminal fragment of 24-kDa FGF2, is mediated by neuropilin 1

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL TELOPEPTIDE; CARBOXY TERMINAL TELOPEPTIDE; FIBROBLAST GROWTH FACTOR 2; HEPARAN SULFATE; HEPARIN; LD 22 4; MEMBRANE RECEPTOR; NEUROPILIN 1; RECOMBINANT GROWTH FACTOR; UNCLASSIFIED DRUG;

EID: 84878617011     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-3015     Document Type: Article
Times cited : (17)

References (43)
  • 1
    • 0037163024 scopus 로고    scopus 로고
    • Inhibition of cell migration and angiogenesis by the amino-terminal fragment of 24kD basic fibroblast growth factor
    • Ding L, Donate F, Parry GC, Guan X, Maher P, Levin EG. Inhibition of cell migration and angiogenesis by the amino-terminal fragment of 24kD basic fibroblast growth factor. J Biol Chem 2002;277:3-61.
    • (2002) J Biol Chem , vol.277 , pp. 3-61
    • Ding, L.1    Donate, F.2    Parry, G.C.3    Guan, X.4    Maher, P.5    Levin, E.G.6
  • 2
    • 1642344519 scopus 로고    scopus 로고
    • Suppression of tumor growth and angiogenesis in vivo by a truncated form of 24-kd fibroblast growth factor (FGF)-2
    • Levin EG, Sikora L, Ding L, Rao SP, Sriramarao P. Suppression of tumor growth and angiogenesis in vivo by a truncated form of 24-kd fibroblast growth factor (FGF)-2. Am J Pathol 2004;164:3-90.
    • (2004) Am J Pathol , vol.164 , pp. 3-90
    • Levin, E.G.1    Sikora, L.2    Ding, L.3    Rao, S.P.4    Sriramarao, P.5
  • 3
    • 64049107670 scopus 로고    scopus 로고
    • FAK mediates the inhibition of glioma cell migration by truncated 24 kDa FGF-2
    • Lin AH, Eliceiri BP, Levin EG. FAK mediates the inhibition of glioma cell migration by truncated 24 kDa FGF-2. BiochemBiophys Res Commun 2009;382:3-7.
    • (2009) BiochemBiophys Res Commun , vol.382 , pp. 3-7
    • Lin, A.H.1    Eliceiri, B.P.2    Levin, E.G.3
  • 4
    • 27144509821 scopus 로고    scopus 로고
    • Cancer therapy through control of cell migration
    • Levin EG. Cancer therapy through control of cell migration. Curr Cancer Drug Targets 2005;5:505-18.
    • (2005) Curr Cancer Drug Targets , vol.5 , pp. 505-518
    • Levin, E.G.1
  • 5
    • 0032898893 scopus 로고    scopus 로고
    • Dual activities of 22-24 kDA basic fibroblast growth factor: Inhibition of migration and stimulation of proliferation
    • Piotrowicz RS, Maher PA, Levin EG. Dual activities of 22-24 kDA basic fibroblast growth factor: inhibition of migration and stimulation of proliferation. J Cell Physiol 1999;178:3-53.
    • (1999) J Cell Physiol , vol.178 , pp. 3-53
    • Piotrowicz, R.S.1    Maher, P.A.2    Levin, E.G.3
  • 6
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003;9:3-76.
    • (2003) Nat Med , vol.9 , pp. 3-76
    • Ferrara, N.1    Gerber, H.P.2    Lecouter, J.3
  • 7
    • 42449148407 scopus 로고    scopus 로고
    • Neuropilins: Structure, function and role in disease
    • Pellet-many C, Frankel P, Jia H, Zachary I. Neuropilins: structure, function and role in disease. Biochem J 2008;411:3-26.
    • (2008) Biochem J , vol.411 , pp. 3-26
    • Pellet-Many, C.1    Frankel, P.2    Jia, H.3    Zachary, I.4
  • 9
    • 34548235938 scopus 로고    scopus 로고
    • Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting
    • Pan Q, Chathery Y, Wu Y, Rathore N, Tong RK, Peale F, et al. Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting. J Biol Chem 2007;282:3-56.
    • (2007) J Biol Chem , vol.282 , pp. 3-56
    • Pan, Q.1    Chathery, Y.2    Wu, Y.3    Rathore, N.4    Tong, R.K.5    Peale, F.6
  • 10
    • 79954559053 scopus 로고    scopus 로고
    • Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas
    • Pellet-many C, Frankel P, Evans IM, Jünemann-Ramírez M, Zachary I. Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas. Biochem J 2011; 435:3-618.
    • (2011) Biochem J , vol.435 , pp. 3-618
    • Pellet-Many, C.1    Frankel, P.2    Evans, I.M.3    Jünemann-Ramírez, M.4    Zachary, I.5
  • 11
    • 0035873074 scopus 로고    scopus 로고
    • Semaphorin 3A-vascular endothelial growth factor-165 balance mediates migration and apoptosis of neural progenitor cells by the recruitment of shared receptor
    • Bagnard D, Vaillant C, Khuth ST, Dufay N, Lohrum M, Puschel AW, et al. Semaphorin 3A-vascular endothelial growth factor-165 balance mediates migration and apoptosis of neural progenitor cells by the recruitment of shared receptor. J Neurosci 2001;21:3-41.
    • (2001) J Neurosci , vol.21 , pp. 3-41
    • Bagnard, D.1    Vaillant, C.2    Khuth, S.T.3    Dufay, N.4    Lohrum, M.5    Puschel, A.W.6
  • 12
    • 76349096681 scopus 로고    scopus 로고
    • Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity
    • Jia H, Cheng L, Tickner M, Bagherzadeh A, Selwood D, Zachary I. Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity. Br J Cancer 2010;102:541-52.
    • (2010) Br J Cancer , vol.102 , pp. 541-552
    • Jia, H.1    Cheng, L.2    Tickner, M.3    Bagherzadeh, A.4    Selwood, D.5    Zachary, I.6
  • 13
    • 33747152506 scopus 로고    scopus 로고
    • Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration
    • Favier B, Alam A, Barron P, Bonnin J, Laboudie P, Fons P, et al. Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration. Blood 2006;108:3-50.
    • (2006) Blood , vol.108 , pp. 3-50
    • Favier, B.1    Alam, A.2    Barron, P.3    Bonnin, J.4    Laboudie, P.5    Fons, P.6
  • 14
    • 0034282885 scopus 로고    scopus 로고
    • The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor Flt-1
    • Fuh G, Garcia KC, de Vos AM. The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor Flt-1. J Biol Chem 2000;275:3-5.
    • (2000) J Biol Chem , vol.275 , pp. 3-5
    • Fuh, G.1    Garcia, K.C.2    De Vos, A.M.3
  • 15
    • 0037124068 scopus 로고    scopus 로고
    • Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165
    • Gu C, Limberg BJ, Whitaker GB, Perman B, Leahy DJ, Rosenbaum JS, et al. Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165. J Biol Chem 2002;277:3-76.
    • (2002) J Biol Chem , vol.277 , pp. 3-76
    • Gu, C.1    Limberg, B.J.2    Whitaker, G.B.3    Perman, B.4    Leahy, D.J.5    Rosenbaum, J.S.6
  • 17
    • 33845991161 scopus 로고    scopus 로고
    • Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth
    • Pan Q, Chanthery Y, Liang WC, Stawicki S, Mak J, Rathore N, et al. Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. Cancer Cell 2007;11:53-67.
    • (2007) Cancer Cell , vol.11 , pp. 53-67
    • Pan, Q.1    Chanthery, Y.2    Liang, W.C.3    Stawicki, S.4    Mak, J.5    Rathore, N.6
  • 18
    • 77950911871 scopus 로고    scopus 로고
    • Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells
    • Ball SG, Bayley C, Shuttleworth CA, Kielty CM. Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells. Biochem J 2010;427:3-40.
    • (2010) Biochem J , vol.427 , pp. 3-40
    • Ball, S.G.1    Bayley, C.2    Shuttleworth, C.A.3    Kielty, C.M.4
  • 19
    • 79952255709 scopus 로고    scopus 로고
    • Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells
    • Evans IM, Yamaji M, Britton G, Pellet-many C, Lockie C, Zachary IC, et al. Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells. Mol Cell Biol 2011;31:3-85.
    • (2011) Mol Cell Biol , vol.31 , pp. 3-85
    • Evans, I.M.1    Yamaji, M.2    Britton, G.3    Pellet-Many, C.4    Lockie, C.5    Zachary, I.C.6
  • 20
    • 34547931473 scopus 로고    scopus 로고
    • Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF//SF autocrine pathway
    • Hu B, Guo P, Bar-Joseph I, Imanishi Y, Jarzynka MJ, Bogler O, et al. Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF//SF autocrine pathway. Oncogene 2007; 26:3-86.
    • (2007) Oncogene , vol.26 , pp. 3-86
    • Hu, B.1    Guo, P.2    Bar-Joseph, I.3    Imanishi, Y.4    Jarzynka, M.J.5    Bogler, O.6
  • 21
    • 0037025311 scopus 로고    scopus 로고
    • Neuropilin-1 binds vascular endothelial growth factor 165, placenta growth factor-2, and heparin via its b1b2 domain
    • Mamluk R, Gechtman Z, Kutcher ME, Gasiunas N, Gallagher J, Klagsbrun M. Neuropilin-1 binds vascular endothelial growth factor 165, placenta growth factor-2, and heparin via its b1b2 domain. J BiolChem 2002;277:3-25.
    • (2002) J BiolChem , vol.277 , pp. 3-25
    • Mamluk, R.1    Gechtman, Z.2    Kutcher, M.E.3    Gasiunas, N.4    Gallagher, J.5    Klagsbrun, M.6
  • 22
    • 20244362645 scopus 로고    scopus 로고
    • Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2
    • West DC, Rees CG, Duchesne L, Patey SJ, Terry CJ, Turnbull JE, et al. Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2. J Biol Chem 2005;280:3-64.
    • (2005) J Biol Chem , vol.280 , pp. 3-64
    • West, D.C.1    Rees, C.G.2    Duchesne, L.3    Patey, S.J.4    Terry, C.J.5    Turnbull, J.E.6
  • 24
    • 33745063095 scopus 로고    scopus 로고
    • The role of neuropilins in cancer
    • Ellis LM. The role of neuropilins in cancer. Mol Cancer Ther 2006;5: 3-107.
    • (2006) Mol Cancer Ther , vol.5 , pp. 3-107
    • Ellis, L.M.1
  • 27
    • 33746320397 scopus 로고    scopus 로고
    • Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling
    • Shintani Y, Takashima S, Asano Y, Kato H, Liao Y, Yamazaki S, et al. Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling. EMBO J 2006;25:3-55.
    • (2006) EMBO J , vol.25 , pp. 3-55
    • Shintani, Y.1    Takashima, S.2    Asano, Y.3    Kato, H.4    Liao, Y.5    Yamazaki, S.6
  • 28
    • 79959667277 scopus 로고    scopus 로고
    • Molecular aspects of HTLV-1 entry: Functional domains of the HTLV-1 surface subunit (SU) and their relationships to the entry receptors
    • Jones KS, Lambert S, Bouttier M, Bénit L, Ruscetti FW, Hermine O, et al. Molecular aspects of HTLV-1 entry: functional domains of the HTLV-1 surface subunit (SU) and their relationships to the entry receptors. Viruses 2011;3:3-810.
    • (2011) Viruses , vol.3 , pp. 3-810
    • Jones, K.S.1    Lambert, S.2    Bouttier, M.3    Bénit, L.4    Ruscetti, F.W.5    Hermine, O.6
  • 29
    • 81755180517 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans mediate the angiogenic activity of the vascular endothelial growth factor receptor-2 agonist gremlin
    • Chiodelli P, Mitola S, Ravelli C, Oreste P, Rusnati M, Presta M. Heparan sulfate proteoglycans mediate the angiogenic activity of the vascular endothelial growth factor receptor-2 agonist gremlin. Arterio Thromb Vasc Biol 2011;31:e116-27.
    • (2011) Arterio Thromb Vasc Biol , vol.31
    • Chiodelli, P.1    Mitola, S.2    Ravelli, C.3    Oreste, P.4    Rusnati, M.5    Presta, M.6
  • 30
    • 70349482671 scopus 로고    scopus 로고
    • C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
    • Teesalu T, Sugahara KN, Kotamraju VR, Ruoslahti E. C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration. Proc Natl Acad Sci U S A 2009;106:3-62.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3-62
    • Teesalu, T.1    Sugahara, K.N.2    Kotamraju, V.R.3    Ruoslahti, E.4
  • 31
    • 33646822526 scopus 로고    scopus 로고
    • Tuftsin binds neuropilin-1 through a sequence similar to that encoded by exon 8 of vascular endothelial growth factor
    • von Wronski MA, Raju N, Pillai R, Bogdan NJ, Marinelli ER, Nanjappan P, et al. Tuftsin binds neuropilin-1 through a sequence similar to that encoded by exon 8 of vascular endothelial growth factor. J Biol Chem 2006;281:3-10.
    • (2006) J Biol Chem , vol.281 , pp. 3-10
    • Von Wronski, M.A.1    Raju, N.2    Pillai, R.3    Bogdan, N.J.4    Marinelli, E.R.5    Nanjappan, P.6
  • 33
    • 36148969690 scopus 로고    scopus 로고
    • Structure function analysis of the antiangiogenic ATWLPPR peptide inhibiting VEGF165 binding to neuropilin-1 and molecular dynamics simulations of the ATWLPPR/neuropilin-1 complex
    • Starzec A, Ladam P, Vassy R, Badache S, Bouchemal N, Navaza A, et al. Structure function analysis of the antiangiogenic ATWLPPR peptide inhibiting VEGF165 binding to neuropilin-1 and molecular dynamics simulations of the ATWLPPR/neuropilin-1 complex. Peptides 2007;28:2397-402.
    • (2007) Peptides , vol.28 , pp. 2397-2402
    • Starzec, A.1    Ladam, P.2    Vassy, R.3    Badache, S.4    Bouchemal, N.5    Navaza, A.6
  • 34
    • 33748479489 scopus 로고    scopus 로고
    • A VEGF-A splice variant defective for heparan sulfate and neuropilin-1 binding shows attenuated signaling through VEGFR-2
    • Cébe Suarez S, Pieren M, Cariolato L, Arn S, Hoffmann U, Bogucki A, et al. A VEGF-A splice variant defective for heparan sulfate and neuropilin-1 binding shows attenuated signaling through VEGFR-2. Cell Mol Life Sci 2006;63:3-77.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 3-77
    • Cébe Suarez, S.1    Pieren, M.2    Cariolato, L.3    Arn, S.4    Hoffmann, U.5    Bogucki, A.6
  • 35
    • 0024584913 scopus 로고
    • Molecular modeling of protein-glycosaminoglycan interactions
    • Cardin AD, Weintraub HJ. Molecular modeling of protein-glycosaminoglycan interactions. Arterio Thromb Vasc Biol 1989;9: 3-32.
    • (1989) Arterio Thromb Vasc Biol , vol.9 , pp. 3-32
    • Cardin, A.D.1    Weintraub, H.J.2
  • 36
    • 84892625819 scopus 로고    scopus 로고
    • G protein coupled receptor oligomerization
    • Breitwieser GE. G protein coupled receptor oligomerization. Circ Res 2004;94:3-27.
    • (2004) Circ Res , vol.94 , pp. 3-27
    • Breitwieser, G.E.1
  • 38
    • 0037145061 scopus 로고    scopus 로고
    • Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
    • Schlessinger J. Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 2002;110:669-72.
    • (2002) Cell , vol.110 , pp. 669-672
    • Schlessinger, J.1
  • 39
  • 40
    • 77951622512 scopus 로고    scopus 로고
    • Peptidebased interference of the transmembrane domain of neuropilin-1 inhibits glioma growth in vivo
    • Nasarre C, Roth M, Jacob L, Roth L, Koncina E, Thien A, et al. Peptidebased interference of the transmembrane domain of neuropilin-1 inhibits glioma growth in vivo. Oncogene 2010;29:3-92.
    • (2010) Oncogene , vol.29 , pp. 3-92
    • Nasarre, C.1    Roth, M.2    Jacob, L.3    Roth, L.4    Koncina, E.5    Thien, A.6
  • 41
    • 58849090461 scopus 로고    scopus 로고
    • Neuropilin-1/GIPC1 signaling regulates a5b1 integrin traffic and function in endothelial cells
    • Valdembri D, Caswell P, Anderson K, Schwarz J, König I, et al. Neuropilin-1/GIPC1 signaling regulates a5b1 integrin traffic and function in endothelial cells. Plos Biol 2009;7:25.
    • (2009) Plos Biol , vol.7 , pp. 25
    • Valdembri, D.1    Caswell, P.2    Anderson, K.3    Schwarz, J.4    König, I.5
  • 42
    • 14944344614 scopus 로고    scopus 로고
    • Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2
    • Murga M, Fernandez-Capetillo O, Tosato G. Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2. Blood 2005;105:1992-9.
    • (2005) Blood , vol.105 , pp. 1992-1999
    • Murga, M.1    Fernandez-Capetillo, O.2    Tosato, G.3
  • 43
    • 33845678052 scopus 로고    scopus 로고
    • C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis
    • Wang L, Mukhopadhyay D, Xu X. C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis. FASEB J 2006;20:3-5.
    • (2006) FASEB J , vol.20 , pp. 3-5
    • Wang, L.1    Mukhopadhyay, D.2    Xu, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.