메뉴 건너뛰기




Volumn 8, Issue 5, 2013, Pages

Aspirin Minimized the Pro-Metastasis Effect of Sorafenib and Improved Survival by Up-Regulating HTATIP2 in Hepatocellular Carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CYCLOOXYGENASE 2; PROTEIN HTATIP2; SORAFENIB; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84878604802     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065023     Document Type: Article
Times cited : (49)

References (50)
  • 2
    • 71249126197 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma in Asia: consensus statement from the Asian Oncology Summit 2009
    • Poon D, Anderson BO, Chen LT, Tanaka K, Lau WY, et al. (2009) Management of hepatocellular carcinoma in Asia: consensus statement from the Asian Oncology Summit 2009. Lancet Oncol 10: 1111-1118.
    • (2009) Lancet Oncol , vol.10 , pp. 1111-1118
    • Poon, D.1    Anderson, B.O.2    Chen, L.T.3    Tanaka, K.4    Lau, W.Y.5
  • 3
    • 23044488800 scopus 로고    scopus 로고
    • Hepatocellular carcinoma surgery-review of the past and prospects for the 21st century
    • Tang ZY, (2005) Hepatocellular carcinoma surgery-review of the past and prospects for the 21st century. J Surg Oncol 91: 95-96.
    • (2005) J Surg Oncol , vol.91 , pp. 95-96
    • Tang, Z.Y.1
  • 5
    • 57749189578 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
    • Cheng AL, Kang YK, Chen Z, Tsao CJ, Qin S, et al. (2009) Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 10: 25-34.
    • (2009) Lancet Oncol , vol.10 , pp. 25-34
    • Cheng, A.L.1    Kang, Y.K.2    Chen, Z.3    Tsao, C.J.4    Qin, S.5
  • 6
    • 70350642097 scopus 로고    scopus 로고
    • The reverse side of the victory: flare up of symptoms after discontinuation of sunitinib or sorafenib in renal cell cancer patients. A report of three cases
    • Desar IM, Mulder SF, Stillebroer AB, van Spronsen DJ, van der Graaf WT, et al. (2009) The reverse side of the victory: flare up of symptoms after discontinuation of sunitinib or sorafenib in renal cell cancer patients. A report of three cases. Acta Oncol 48: 927-931.
    • (2009) Acta Oncol , vol.48 , pp. 927-931
    • Desar, I.M.1    Mulder, S.F.2    Stillebroer, A.B.3    van Spronsen, D.J.4    van der Graaf, W.T.5
  • 7
    • 50849089255 scopus 로고    scopus 로고
    • Reversible tumor growth acceleration following bevacizumab interruption in metastatic colorectal cancer patients scheduled for surgery
    • Cacheux W, Boisserie T, Staudacher L, Vignaux O, Dousset B, et al. (2008) Reversible tumor growth acceleration following bevacizumab interruption in metastatic colorectal cancer patients scheduled for surgery. Ann Oncol 19: 1659-1661.
    • (2008) Ann Oncol , vol.19 , pp. 1659-1661
    • Cacheux, W.1    Boisserie, T.2    Staudacher, L.3    Vignaux, O.4    Dousset, B.5
  • 8
    • 79551521053 scopus 로고    scopus 로고
    • Phase III trial assessing bevacizumab in stages II and III carcinoma of the colon: results of NSABP protocol C-08
    • Allegra CJ, Yothers G, O'Connell MJ, Sharif S, Petrelli NJ, et al. (2011) Phase III trial assessing bevacizumab in stages II and III carcinoma of the colon: results of NSABP protocol C-08. J Clin Oncol 29: 11-16.
    • (2011) J Clin Oncol , vol.29 , pp. 11-16
    • Allegra, C.J.1    Yothers, G.2    O'Connell, M.J.3    Sharif, S.4    Petrelli, N.J.5
  • 9
    • 79960977418 scopus 로고    scopus 로고
    • The outcome of patients treated with sunitinib prior to planned nephrectomy in metastatic clear cell renal cancer
    • Powles T, Blank C, Chowdhury S, Horenblas S, Peters J, et al. (2011) The outcome of patients treated with sunitinib prior to planned nephrectomy in metastatic clear cell renal cancer. Eur Urol 60: 448-454.
    • (2011) Eur Urol , vol.60 , pp. 448-454
    • Powles, T.1    Blank, C.2    Chowdhury, S.3    Horenblas, S.4    Peters, J.5
  • 10
    • 60649087564 scopus 로고    scopus 로고
    • Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
    • Ebos JM, Lee CR, Cruz-Munoz W, Bjarnason GA, Christensen JG, et al. (2009) Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 15: 232-239.
    • (2009) Cancer Cell , vol.15 , pp. 232-239
    • Ebos, J.M.1    Lee, C.R.2    Cruz-Munoz, W.3    Bjarnason, G.A.4    Christensen, J.G.5
  • 11
    • 60649106195 scopus 로고    scopus 로고
    • Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
    • Paez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, et al. (2009) Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15: 220-231.
    • (2009) Cancer Cell , vol.15 , pp. 220-231
    • Paez-Ribes, M.1    Allen, E.2    Hudock, J.3    Takeda, T.4    Okuyama, H.5
  • 12
    • 84869758057 scopus 로고    scopus 로고
    • Sorafenib Down-regulates Expression of HTATIP2 to Promote Invasiveness and Metastasis of Orthotopic Hepatocellular Carcinoma Tumors in Mice
    • Zhang W, Sun HC, Wang WQ, Zhang QB, Zhuang PY, et al. (2012) Sorafenib Down-regulates Expression of HTATIP2 to Promote Invasiveness and Metastasis of Orthotopic Hepatocellular Carcinoma Tumors in Mice. Gastroenterology.
    • (2012) Gastroenterology
    • Zhang, W.1    Sun, H.C.2    Wang, W.Q.3    Zhang, Q.B.4    Zhuang, P.Y.5
  • 13
    • 78650215449 scopus 로고    scopus 로고
    • Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials
    • Rothwell PM, Wilson M, Elwin CE, Norrving B, Algra A, et al. (2010) Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials. Lancet 376: 1741-1750.
    • (2010) Lancet , vol.376 , pp. 1741-1750
    • Rothwell, P.M.1    Wilson, M.2    Elwin, C.E.3    Norrving, B.4    Algra, A.5
  • 14
    • 78650825618 scopus 로고    scopus 로고
    • Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials
    • Rothwell PM, Fowkes FG, Belch JF, Ogawa H, Warlow CP, et al. (2011) Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 377: 31-41.
    • (2011) Lancet , vol.377 , pp. 31-41
    • Rothwell, P.M.1    Fowkes, F.G.2    Belch, J.F.3    Ogawa, H.4    Warlow, C.P.5
  • 15
    • 84863399038 scopus 로고    scopus 로고
    • Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials
    • Rothwell PM, Wilson M, Price JF, Belch JF, Meade TW, et al. (2012) Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials. Lancet 379: 1591-1601.
    • (2012) Lancet , vol.379 , pp. 1591-1601
    • Rothwell, P.M.1    Wilson, M.2    Price, J.F.3    Belch, J.F.4    Meade, T.W.5
  • 16
    • 34447342251 scopus 로고    scopus 로고
    • Effects of acetylsalicylic acid and acetic acid solutions on VX2 liver carcinoma in rabbits. In vivo analysis
    • Saad-Hossne R, Prado RG, Hossne WS, (2007) Effects of acetylsalicylic acid and acetic acid solutions on VX2 liver carcinoma in rabbits. In vivo analysis. Acta Cir Bras 22: 299-308.
    • (2007) Acta Cir Bras , vol.22 , pp. 299-308
    • Saad-Hossne, R.1    Prado, R.G.2    Hossne, W.S.3
  • 17
    • 18344372909 scopus 로고    scopus 로고
    • Aspirin and NS-398 inhibit hepatocyte growth factor-induced invasiveness of human hepatoma cells
    • Abiru S, Nakao K, Ichikawa T, Migita K, Shigeno M, et al. (2002) Aspirin and NS-398 inhibit hepatocyte growth factor-induced invasiveness of human hepatoma cells. Hepatology 35: 1117-1124.
    • (2002) Hepatology , vol.35 , pp. 1117-1124
    • Abiru, S.1    Nakao, K.2    Ichikawa, T.3    Migita, K.4    Shigeno, M.5
  • 18
    • 84863412124 scopus 로고    scopus 로고
    • Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials
    • Rothwell PM, Price JF, Fowkes FG, Zanchetti A, Roncaglioni MC, et al. (2012) Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials. Lancet 379: 1602-1612.
    • (2012) Lancet , vol.379 , pp. 1602-1612
    • Rothwell, P.M.1    Price, J.F.2    Fowkes, F.G.3    Zanchetti, A.4    Roncaglioni, M.C.5
  • 20
    • 4344589523 scopus 로고    scopus 로고
    • Stepwise metastatic human hepatocellular carcinoma cell model system with multiple metastatic potentials established through consecutive in vivo selection and studies on metastatic characteristics
    • Li Y, Tian B, Yang J, Zhao L, Wu X, et al. (2004) Stepwise metastatic human hepatocellular carcinoma cell model system with multiple metastatic potentials established through consecutive in vivo selection and studies on metastatic characteristics. J Cancer Res Clin Oncol 130: 460-468.
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 460-468
    • Li, Y.1    Tian, B.2    Yang, J.3    Zhao, L.4    Wu, X.5
  • 21
    • 47149089187 scopus 로고    scopus 로고
    • Thirty-kilodalton Tat-interacting protein suppresses tumor metastasis by inhibition of osteopontin transcription in human hepatocellular carcinoma
    • Zhao J, Lu B, Xu H, Tong X, Wu G, et al. (2008) Thirty-kilodalton Tat-interacting protein suppresses tumor metastasis by inhibition of osteopontin transcription in human hepatocellular carcinoma. Hepatology 48: 265-275.
    • (2008) Hepatology , vol.48 , pp. 265-275
    • Zhao, J.1    Lu, B.2    Xu, H.3    Tong, X.4    Wu, G.5
  • 22
    • 49249118307 scopus 로고    scopus 로고
    • TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma
    • Zhao J, Chen J, Lu B, Dong L, Wang H, et al. (2008) TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma. Cancer Res 68: 4133-4141.
    • (2008) Cancer Res , vol.68 , pp. 4133-4141
    • Zhao, J.1    Chen, J.2    Lu, B.3    Dong, L.4    Wang, H.5
  • 23
    • 77954229219 scopus 로고    scopus 로고
    • Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects
    • Zhang W, Zhu XD, Sun HC, Xiong YQ, Zhuang PY, et al. (2010) Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects. Clin Cancer Res 16: 3420-3430.
    • (2010) Clin Cancer Res , vol.16 , pp. 3420-3430
    • Zhang, W.1    Zhu, X.D.2    Sun, H.C.3    Xiong, Y.Q.4    Zhuang, P.Y.5
  • 24
    • 33847118123 scopus 로고    scopus 로고
    • Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models
    • Chang YS, Adnane J, Trail PA, Levy J, Henderson A, et al. (2007) Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models. Cancer Chemother Pharmacol 59: 561-574.
    • (2007) Cancer Chemother Pharmacol , vol.59 , pp. 561-574
    • Chang, Y.S.1    Adnane, J.2    Trail, P.A.3    Levy, J.4    Henderson, A.5
  • 25
    • 80053994835 scopus 로고    scopus 로고
    • Aspirin and cancer: has aspirin been overlooked as an adjuvant therapy?
    • Langley RE, Burdett S, Tierney JF, Cafferty F, Parmar MK, et al. (2011) Aspirin and cancer: has aspirin been overlooked as an adjuvant therapy? Br J Cancer 105: 1107-1113.
    • (2011) Br J Cancer , vol.105 , pp. 1107-1113
    • Langley, R.E.1    Burdett, S.2    Tierney, J.F.3    Cafferty, F.4    Parmar, M.K.5
  • 26
    • 77952309402 scopus 로고    scopus 로고
    • Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice
    • de Groot JF, Fuller G, Kumar AJ, Piao Y, Eterovic K, et al. (2010) Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice. Neuro Oncol 12: 233-242.
    • (2010) Neuro Oncol , vol.12 , pp. 233-242
    • de Groot, J.F.1    Fuller, G.2    Kumar, A.J.3    Piao, Y.4    Eterovic, K.5
  • 27
    • 33749573178 scopus 로고    scopus 로고
    • Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways
    • Yu C, Friday BB, Lai JP, Yang L, Sarkaria J, et al. (2006) Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways. Mol Cancer Ther 5: 2378-2387.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2378-2387
    • Yu, C.1    Friday, B.B.2    Lai, J.P.3    Yang, L.4    Sarkaria, J.5
  • 28
    • 33845371047 scopus 로고    scopus 로고
    • Sorafenib is efficacious and tolerated in combination with cytotoxic or cytostatic agents in preclinical models of human non-small cell lung carcinoma
    • Carter CA, Chen C, Brink C, Vincent P, Maxuitenko YY, et al. (2007) Sorafenib is efficacious and tolerated in combination with cytotoxic or cytostatic agents in preclinical models of human non-small cell lung carcinoma. Cancer Chemother Pharmacol 59: 183-195.
    • (2007) Cancer Chemother Pharmacol , vol.59 , pp. 183-195
    • Carter, C.A.1    Chen, C.2    Brink, C.3    Vincent, P.4    Maxuitenko, Y.Y.5
  • 29
    • 79959944026 scopus 로고    scopus 로고
    • Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?
    • De Bock K, Mazzone M, Carmeliet P, (2011) Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not? Nat Rev Clin Oncol 8: 393-404.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 393-404
    • De Bock, K.1    Mazzone, M.2    Carmeliet, P.3
  • 30
    • 26644471951 scopus 로고    scopus 로고
    • Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
    • Casanovas O, Hicklin DJ, Bergers G, Hanahan D, (2005) Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell 8: 299-309.
    • (2005) Cancer Cell , vol.8 , pp. 299-309
    • Casanovas, O.1    Hicklin, D.J.2    Bergers, G.3    Hanahan, D.4
  • 31
    • 79952740612 scopus 로고    scopus 로고
    • Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma
    • Keunen O, Johansson M, Oudin A, Sanzey M, Rahim SA, et al. (2011) Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proc Natl Acad Sci U S A 108: 3749-3754.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 3749-3754
    • Keunen, O.1    Johansson, M.2    Oudin, A.3    Sanzey, M.4    Rahim, S.A.5
  • 32
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M, (2010) Immunity, inflammation, and cancer. Cell 140: 883-899.
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 33
    • 77950355734 scopus 로고    scopus 로고
    • Anti-inflammatory Agents: Present and Future
    • Dinarello CA, (2010) Anti-inflammatory Agents: Present and Future. Cell 140: 935-950.
    • (2010) Cell , vol.140 , pp. 935-950
    • Dinarello, C.A.1
  • 34
    • 84864681003 scopus 로고    scopus 로고
    • Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B
    • Sitia G, Aiolfi R, Di Lucia P, Mainetti M, Fiocchi A, et al. (2012) Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B. Proc Natl Acad Sci U S A. 109: E2165-2172.
    • (2012) Proc Natl Acad Sci U S A , vol.109
    • Sitia, G.1    Aiolfi, R.2    Di Lucia, P.3    Mainetti, M.4    Fiocchi, A.5
  • 36
    • 84868641794 scopus 로고    scopus 로고
    • Association between nucleoside analogues and risk of hepatitis B virus-related hepatocellular carcinoma recurrence following liver resection
    • Wu CY, Chen YJ, Ho HJ, Hsu YC, Kuo KN, et al. (2012) Association between nucleoside analogues and risk of hepatitis B virus-related hepatocellular carcinoma recurrence following liver resection. JAMA 308: 1906-1914.
    • (2012) JAMA , vol.308 , pp. 1906-1914
    • Wu, C.Y.1    Chen, Y.J.2    Ho, H.J.3    Hsu, Y.C.4    Kuo, K.N.5
  • 37
    • 0017645897 scopus 로고
    • Antiproliferative activity of anti-inflammatory drugs in two mammalian cell culture lines
    • Hial V, De Mello MC, Horakova Z, Beaven MA, (1977) Antiproliferative activity of anti-inflammatory drugs in two mammalian cell culture lines. J Pharmacol Exp Ther 202: 446-454.
    • (1977) J Pharmacol Exp Ther , vol.202 , pp. 446-454
    • Hial, V.1    De Mello, M.C.2    Horakova, Z.3    Beaven, M.A.4
  • 38
    • 0036808604 scopus 로고    scopus 로고
    • Suppression of lung metastasis by aspirin but not indomethacin in an in vivo model of chemically induced hepatocellular carcinoma
    • Futakuchi M, Ogawa K, Sano M, Tamano S, Takeshita F, et al. (2002) Suppression of lung metastasis by aspirin but not indomethacin in an in vivo model of chemically induced hepatocellular carcinoma. Jpn J Cancer Res 93: 1175-1181.
    • (2002) Jpn J Cancer Res , vol.93 , pp. 1175-1181
    • Futakuchi, M.1    Ogawa, K.2    Sano, M.3    Tamano, S.4    Takeshita, F.5
  • 39
    • 1142275252 scopus 로고    scopus 로고
    • Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma
    • Futakuchi M, Ogawa K, Tamano S, Takahashi S, Shirai T, (2004) Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma. Cancer Sci 95: 18-24.
    • (2004) Cancer Sci , vol.95 , pp. 18-24
    • Futakuchi, M.1    Ogawa, K.2    Tamano, S.3    Takahashi, S.4    Shirai, T.5
  • 40
    • 33745922882 scopus 로고    scopus 로고
    • TIP30 inhibits growth of HCC cell lines and inhibits HCC xenografts in mice in combination with 5-FU
    • Zhao J, Zhang X, Shi M, Xu H, Jin J, et al. (2006) TIP30 inhibits growth of HCC cell lines and inhibits HCC xenografts in mice in combination with 5-FU. Hepatology 44: 205-215.
    • (2006) Hepatology , vol.44 , pp. 205-215
    • Zhao, J.1    Zhang, X.2    Shi, M.3    Xu, H.4    Jin, J.5
  • 41
    • 84860281277 scopus 로고    scopus 로고
    • Aspirin enhances doxorubicin-induced apoptosis and reduces tumor growth in human hepatocellular carcinoma cells in vitro and in vivo
    • Hossain MA, Kim DH, Jang JY, Kang YJ, Yoon JH, et al. (2012) Aspirin enhances doxorubicin-induced apoptosis and reduces tumor growth in human hepatocellular carcinoma cells in vitro and in vivo. Int J Oncol 40: 1636-1642.
    • (2012) Int J Oncol , vol.40 , pp. 1636-1642
    • Hossain, M.A.1    Kim, D.H.2    Jang, J.Y.3    Kang, Y.J.4    Yoon, J.H.5
  • 42
    • 80052043989 scopus 로고    scopus 로고
    • Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells
    • Raza H, John A, Benedict S, (2011) Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells. Eur J Pharmacol 668: 15-24.
    • (2011) Eur J Pharmacol , vol.668 , pp. 15-24
    • Raza, H.1    John, A.2    Benedict, S.3
  • 43
    • 65849268320 scopus 로고    scopus 로고
    • Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials
    • Baigent C, Blackwell L, Collins R, Emberson J, Godwin J, et al. (2009) Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet 373: 1849-1860.
    • (2009) Lancet , vol.373 , pp. 1849-1860
    • Baigent, C.1    Blackwell, L.2    Collins, R.3    Emberson, J.4    Godwin, J.5
  • 44
    • 73349100646 scopus 로고    scopus 로고
    • Aspirin for the primary prevention of vascular events?
    • Morgan G, (2009) Aspirin for the primary prevention of vascular events? Public Health 123: 787-788.
    • (2009) Public Health , vol.123 , pp. 787-788
    • Morgan, G.1
  • 45
    • 79955641250 scopus 로고    scopus 로고
    • Long-term use of aspirin and the risk of gastrointestinal bleeding
    • Huang ES, Strate LL, Ho WW, Lee SS, Chan AT, (2011) Long-term use of aspirin and the risk of gastrointestinal bleeding. Am J Med 124: 426-433.
    • (2011) Am J Med , vol.124 , pp. 426-433
    • Huang, E.S.1    Strate, L.L.2    Ho, W.W.3    Lee, S.S.4    Chan, A.T.5
  • 46
    • 40449086665 scopus 로고    scopus 로고
    • Dose translation from animal to human studies revisited
    • Reagan-Shaw S, Nihal M, Ahmad N, (2008) Dose translation from animal to human studies revisited. FASEB J 22: 659-661.
    • (2008) FASEB J , vol.22 , pp. 659-661
    • Reagan-Shaw, S.1    Nihal, M.2    Ahmad, N.3
  • 47
    • 12144275353 scopus 로고    scopus 로고
    • Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding
    • Chan FK, Ching JY, Hung LC, Wong VW, Leung VK, et al. (2005) Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. N Engl J Med 352: 238-244.
    • (2005) N Engl J Med , vol.352 , pp. 238-244
    • Chan, F.K.1    Ching, J.Y.2    Hung, L.C.3    Wong, V.W.4    Leung, V.K.5
  • 48
    • 0035967198 scopus 로고    scopus 로고
    • Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen
    • Chan FK, Chung SC, Suen BY, Lee YT, Leung WK, et al. (2001) Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen. N Engl J Med 344: 967-973.
    • (2001) N Engl J Med , vol.344 , pp. 967-973
    • Chan, F.K.1    Chung, S.C.2    Suen, B.Y.3    Lee, Y.T.4    Leung, W.K.5
  • 49
    • 0037182764 scopus 로고    scopus 로고
    • Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use
    • Lai KC, Lam SK, Chu KM, Wong BC, Hui WM, et al. (2002) Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use. N Engl J Med 346: 2033-2038.
    • (2002) N Engl J Med , vol.346 , pp. 2033-2038
    • Lai, K.C.1    Lam, S.K.2    Chu, K.M.3    Wong, B.C.4    Hui, W.M.5
  • 50
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, et al. (2001) Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 345: 494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.