Aspirin enhances doxorubicin-induced apoptosis and reduces tumor growth in human hepatocellular carcinoma cells in vitro and in vivo

International Journal of Oncology

Volumn 40, Issue 5, 2012, Pages 1636-1642

  Hossain, Mohammad Akbar ^a   Kim, Dong Hwan ^a   Jang, Jung Yoon ^a   Kang, Yong Jung ^a   Yoon, Jeong Hyun ^a   Moon, Jeon Ok ^a   Chung, Hae Young ^a   Kim, Gi Young ^b   Choi, Yung Hyun ^c   Copple, Bryan L ^d   Kim, Nam Deuk ^a  

^a Pusan National University   (South Korea)

^b Jeju National University   (South Korea)

^c Dong Eui University   (South Korea)

^d MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Aspirin; Doxorubicin; Hepatocellular carcinoma; Xenograft model

Indexed keywords

ACETYLSALICYLIC ACID; DOXORUBICIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG POTENTIATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TUMOR XENOGRAFT;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; ASPIRIN; CARCINOMA, HEPATOCELLULAR; CASPASES; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG SYNERGISM; ENZYME ACTIVATION; HEP G2 CELLS; HUMANS; INJECTIONS, INTRAPERITONEAL; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; TIME FACTORS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84860281277     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1359     Document Type: Article

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