메뉴 건너뛰기




Volumn 8, Issue 5, 2013, Pages

Robust Automated Detection of Microstructural White Matter Degeneration in Alzheimer's Disease Using Machine Learning Classification of Multicenter DTI Data

(16)  Dyrba, Martin a   Ewers, Michael b   Wegrzyn, Martin a   Kilimann, Ingo a   Plant, Claudia c,d   Oswald, Annahita e   Meindl, Thomas b   Pievani, Michela f   Bokde, Arun L W g,h   Fellgiebel, Andreas i   Filippi, Massimo j   Hampel, Harald k   Klöppel, Stefan l   Hauenstein, Karlheinz m   Kirste, Thomas m   Teipel, Stefan J a,m  


Author keywords

[No Author keywords available]

Indexed keywords

AGED; ALZHEIMER DISEASE; ANALYTICAL PARAMETERS; ARTICLE; AUTOMATION; BAYES THEOREM; BRAIN MAPPING; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIFFUSION TENSOR IMAGING; DISEASE CLASSIFICATION; FEMALE; FRACTIONAL ANISOTROPY; GRAY MATTER; HUMAN; MACHINE LEARNING; MAJOR CLINICAL STUDY; MALE; MEAN DIFFUSIVITY; MINI MENTAL STATE EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SUPPORT VECTOR MACHINE; VALIDATION PROCESS; WHITE MATTER DEGENERATION;

EID: 84878582129     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064925     Document Type: Article
Times cited : (99)

References (65)
  • 1
    • 80955166403 scopus 로고    scopus 로고
    • Alliance for Aging Research AD Biomarkers Work Group: structural MRI
    • Jack CR, (2011) Alliance for Aging Research AD Biomarkers Work Group: structural MRI. Neurobiology of Aging 32Supplement 1: S48-S57.
    • (2011) Neurobiology of Aging , vol.32
    • Jack, C.R.1
  • 2
    • 34447322271 scopus 로고    scopus 로고
    • Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria
    • Dubois B, Feldman HH, Jacova C, DeKosky ST, Barberger-Gateau P, et al. (2007) Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. The Lancet Neurology 6: 734-746.
    • (2007) The Lancet Neurology , vol.6 , pp. 734-746
    • Dubois, B.1    Feldman, H.H.2    Jacova, C.3    DeKosky, S.T.4    Barberger-Gateau, P.5
  • 3
    • 18544386562 scopus 로고    scopus 로고
    • Increased Aβ Peptides and Reduced Cholesterol and Myelin Proteins Characterize White Matter Degeneration in Alzheimer's Disease
    • Roher AE, Weiss N, Kokjohn TA, Kuo Y-M, Kalback W, et al. (2002) Increased Aβ Peptides and Reduced Cholesterol and Myelin Proteins Characterize White Matter Degeneration in Alzheimer's Disease. Biochemistry 41: 11080-11090.
    • (2002) Biochemistry , vol.41 , pp. 11080-11090
    • Roher, A.E.1    Weiss, N.2    Kokjohn, T.A.3    Kuo, Y.-M.4    Kalback, W.5
  • 4
    • 37849007577 scopus 로고    scopus 로고
    • Diffusion imaging concepts for clinicians
    • Neil JJ, (2008) Diffusion imaging concepts for clinicians. J Magn Reson Imaging 27: 1-7.
    • (2008) J Magn Reson Imaging , vol.27 , pp. 1-7
    • Neil, J.J.1
  • 5
    • 57649219944 scopus 로고    scopus 로고
    • Visualization of peripheral nerve degeneration and regeneration: Monitoring with diffusion tensor tractography
    • Takagi T, Nakamura M, Yamada M, Hikishima K, Momoshima S, et al. (2009) Visualization of peripheral nerve degeneration and regeneration: Monitoring with diffusion tensor tractography. NeuroImage 44: 884-892.
    • (2009) NeuroImage , vol.44 , pp. 884-892
    • Takagi, T.1    Nakamura, M.2    Yamada, M.3    Hikishima, K.4    Momoshima, S.5
  • 6
    • 33747753510 scopus 로고    scopus 로고
    • Diffusion tensor imaging of time-dependent axonal and myelin degradation after corpus callosotomy in epilepsy patients
    • Concha L, Gross DW, Wheatley BM, Beaulieu C, (2006) Diffusion tensor imaging of time-dependent axonal and myelin degradation after corpus callosotomy in epilepsy patients. NeuroImage 32: 1090-1099.
    • (2006) NeuroImage , vol.32 , pp. 1090-1099
    • Concha, L.1    Gross, D.W.2    Wheatley, B.M.3    Beaulieu, C.4
  • 7
    • 0036266137 scopus 로고    scopus 로고
    • White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging
    • Bozzali M, Falini A, Franceschi M, Cercignani M, Zuffi M, et al. (2002) White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging. J Neurol Neurosurg Psychiatry 72: 742-746.
    • (2002) J Neurol Neurosurg Psychiatry , vol.72 , pp. 742-746
    • Bozzali, M.1    Falini, A.2    Franceschi, M.3    Cercignani, M.4    Zuffi, M.5
  • 8
    • 0035949790 scopus 로고    scopus 로고
    • Quantification of tissue damage in AD using diffusion tensor and magnetization transfer MRI
    • Bozzali M, Franceschi M, Falini A, Pontesilli S, Cercignani M, et al. (2001) Quantification of tissue damage in AD using diffusion tensor and magnetization transfer MRI. Neurology 57: 1135-1137.
    • (2001) Neurology , vol.57 , pp. 1135-1137
    • Bozzali, M.1    Franceschi, M.2    Falini, A.3    Pontesilli, S.4    Cercignani, M.5
  • 9
    • 14644403065 scopus 로고    scopus 로고
    • Diffusion tensor imaging of frontal white matter microstructure in early Alzheimer's disease: a preliminary study
    • Choi SJ, Lim KO, Monteiro I, Reisberg B, (2005) Diffusion tensor imaging of frontal white matter microstructure in early Alzheimer's disease: a preliminary study. J Geriatr Psychiatry Neurol 18: 12-19.
    • (2005) J Geriatr Psychiatry Neurol , vol.18 , pp. 12-19
    • Choi, S.J.1    Lim, K.O.2    Monteiro, I.3    Reisberg, B.4
  • 10
    • 19444387408 scopus 로고    scopus 로고
    • Color-coded diffusion-tensor-imaging of posterior cingulate fiber tracts in mild cognitive impairment
    • Fellgiebel A, Muller MJ, Wille P, Dellani PR, Scheurich A, et al. (2005) Color-coded diffusion-tensor-imaging of posterior cingulate fiber tracts in mild cognitive impairment. Neurobiol Aging 26: 1193-1198.
    • (2005) Neurobiol Aging , vol.26 , pp. 1193-1198
    • Fellgiebel, A.1    Muller, M.J.2    Wille, P.3    Dellani, P.R.4    Scheurich, A.5
  • 11
    • 34247562454 scopus 로고    scopus 로고
    • Diffusion tensor imaging of normal appearing white matter and its correlation with cognitive functioning in mild cognitive impairment and Alzheimer's disease
    • Huang J, Auchus AP, (2007) Diffusion tensor imaging of normal appearing white matter and its correlation with cognitive functioning in mild cognitive impairment and Alzheimer's disease. Ann N Y Acad Sci 1097: 259-264.
    • (2007) Ann N Y Acad Sci , vol.1097 , pp. 259-264
    • Huang, J.1    Auchus, A.P.2
  • 12
    • 33646488698 scopus 로고    scopus 로고
    • White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study
    • Medina D, Detoledo-Morrell L, Urresta F, Gabrieli JD, Moseley M, et al. (2006) White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study. Neurobiol Aging 27: 663-672.
    • (2006) Neurobiol Aging , vol.27 , pp. 663-672
    • Medina, D.1    Detoledo-Morrell, L.2    Urresta, F.3    Gabrieli, J.D.4    Moseley, M.5
  • 14
    • 34247540312 scopus 로고    scopus 로고
    • White matter damage in Alzheimer's disease and in mild cognitive impairment: assessment with diffusion tensor MRI using parallel imaging techniques
    • Stahl R, Dietrich O, Teipel SJ, Hampel H, Reiser MF, et al. (2007) White matter damage in Alzheimer's disease and in mild cognitive impairment: assessment with diffusion tensor MRI using parallel imaging techniques. Radiology 243: 483-492.
    • (2007) Radiology , vol.243 , pp. 483-492
    • Stahl, R.1    Dietrich, O.2    Teipel, S.J.3    Hampel, H.4    Reiser, M.F.5
  • 15
    • 33745921756 scopus 로고    scopus 로고
    • Voxel-based detection of white matter abnormalities in mild Alzheimer disease
    • Xie S, Xiao JX, Gong GL, Zang YF, Wang YH, et al. (2006) Voxel-based detection of white matter abnormalities in mild Alzheimer disease. Neurology 66: 1845-1849.
    • (2006) Neurology , vol.66 , pp. 1845-1849
    • Xie, S.1    Xiao, J.X.2    Gong, G.L.3    Zang, Y.F.4    Wang, Y.H.5
  • 16
    • 33846112012 scopus 로고    scopus 로고
    • Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease
    • Zhang Y, Schuff N, Jahng GH, Bayne W, Mori S, et al. (2007) Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease. Neurology 68: 13-19.
    • (2007) Neurology , vol.68 , pp. 13-19
    • Zhang, Y.1    Schuff, N.2    Jahng, G.H.3    Bayne, W.4    Mori, S.5
  • 17
    • 77954515677 scopus 로고    scopus 로고
    • Diagnostic utility of novel MRI-based biomarkers for Alzheimer's disease: diffusion tensor imaging and deformation-based morphometry
    • Friese U, Meindl T, Herpertz SC, Reiser MF, Hampel H, et al. (2010) Diagnostic utility of novel MRI-based biomarkers for Alzheimer's disease: diffusion tensor imaging and deformation-based morphometry. J Alzheimers Dis 20: 477-490.
    • (2010) J Alzheimers Dis , vol.20 , pp. 477-490
    • Friese, U.1    Meindl, T.2    Herpertz, S.C.3    Reiser, M.F.4    Hampel, H.5
  • 18
    • 33947173843 scopus 로고    scopus 로고
    • Multivariate network analysis of fiber tract integrity in Alzheimer's disease
    • Teipel SJ, Stahl R, Dietrich O, Schoenberg SO, Perneczky R, et al. (2007) Multivariate network analysis of fiber tract integrity in Alzheimer's disease. NeuroImage 34: 985-995.
    • (2007) NeuroImage , vol.34 , pp. 985-995
    • Teipel, S.J.1    Stahl, R.2    Dietrich, O.3    Schoenberg, S.O.4    Perneczky, R.5
  • 19
    • 80052364811 scopus 로고    scopus 로고
    • Computer Aided Diagnosis system for Alzheimer Disease using brain Diffusion Tensor Imaging features selected by Pearson's correlation
    • Graña M, Termenon M, Savio A, Gonzalez-Pinto A, Echeveste J, et al. (2011) Computer Aided Diagnosis system for Alzheimer Disease using brain Diffusion Tensor Imaging features selected by Pearson's correlation. Neuroscience Letters 502: 225-229.
    • (2011) Neuroscience Letters , vol.502 , pp. 225-229
    • Graña, M.1    Termenon, M.2    Savio, A.3    Gonzalez-Pinto, A.4    Echeveste, J.5
  • 20
    • 79960638062 scopus 로고    scopus 로고
    • Identification of Conversion from Mild Cognitive Impairment to Alzheimer's Disease Using Multivariate Predictors
    • Cui Y, Liu B, Luo S, Zhen X, Fan M, et al. (2011) Identification of Conversion from Mild Cognitive Impairment to Alzheimer's Disease Using Multivariate Predictors. PLoS ONE 6: e21896.
    • (2011) PLoS ONE , vol.6
    • Cui, Y.1    Liu, B.2    Luo, S.3    Zhen, X.4    Fan, M.5
  • 21
    • 0346770038 scopus 로고    scopus 로고
    • Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease
    • author reply 49-62
    • Bartzokis G (2004) Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. Neurobiol Aging 25: 5-18; author reply 49-62.
    • (2004) Neurobiol Aging , vol.25 , pp. 5-18
    • Bartzokis, G.1
  • 22
    • 0141841829 scopus 로고    scopus 로고
    • Replicability of diffusion tensor imaging measurements of fractional anisotropy and trace in brain
    • Pfefferbaum A, Adalsteinsson E, Sullivan EV, (2003) Replicability of diffusion tensor imaging measurements of fractional anisotropy and trace in brain. J Magn Reson Imaging 18: 427-433.
    • (2003) J Magn Reson Imaging , vol.18 , pp. 427-433
    • Pfefferbaum, A.1    Adalsteinsson, E.2    Sullivan, E.V.3
  • 23
    • 77952879583 scopus 로고    scopus 로고
    • Identical, but not the same: intra-site and inter-site reproducibility of fractional anisotropy measures on two 3.0T scanners
    • Vollmar C, O'Muircheartaigh J, Barker GJ, Symms MR, Thompson P, et al. (2011) Identical, but not the same: intra-site and inter-site reproducibility of fractional anisotropy measures on two 3.0T scanners. NeuroImage 51: 1384-1394.
    • (2011) NeuroImage , vol.51 , pp. 1384-1394
    • Vollmar, C.1    O'Muircheartaigh, J.2    Barker, G.J.3    Symms, M.R.4    Thompson, P.5
  • 25
    • 44249088535 scopus 로고    scopus 로고
    • Structural and functional biomarkers of prodromal Alzheimer's disease: A high-dimensional pattern classification study
    • Fan Y, Resnick SM, Wu X, Davatzikos C, (2008) Structural and functional biomarkers of prodromal Alzheimer's disease: A high-dimensional pattern classification study. NeuroImage 41: 277-285.
    • (2008) NeuroImage , vol.41 , pp. 277-285
    • Fan, Y.1    Resnick, S.M.2    Wu, X.3    Davatzikos, C.4
  • 26
    • 28244492778 scopus 로고    scopus 로고
    • Classifying brain states and determining the discriminating activation patterns: Support Vector Machine on functional MRI data
    • Mourão-Miranda J, Bokde ALW, Christine B, Harald H, Stetter M, (2005) Classifying brain states and determining the discriminating activation patterns: Support Vector Machine on functional MRI data. NeuroImage 28: 980-995.
    • (2005) NeuroImage , vol.28 , pp. 980-995
    • Mourão-Miranda, J.1    Bokde, A.L.W.2    Christine, B.3    Harald, H.4    Stetter, M.5
  • 27
    • 75249106883 scopus 로고    scopus 로고
    • Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease
    • Plant C, Teipel SJ, Oswald A, Böhm C, Meindl T, et al. (2010) Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease. NeuroImage 50: 162-174.
    • (2010) NeuroImage , vol.50 , pp. 162-174
    • Plant, C.1    Teipel, S.J.2    Oswald, A.3    Böhm, C.4    Meindl, T.5
  • 29
    • 34249753618 scopus 로고
    • Support-vector networks
    • Cortes C, Vapnik V, (1995) Support-vector networks. Machine Learning 20: 273-297.
    • (1995) Machine Learning , vol.20 , pp. 273-297
    • Cortes, C.1    Vapnik, V.2
  • 31
    • 39749191312 scopus 로고    scopus 로고
    • Automatic classification of MR scans in Alzheimer's disease
    • Klöppel S, Stonnington CM, Chu C, Draganski B, Scahill R, et al. (2008) Automatic classification of MR scans in Alzheimer's disease. Brain 131: 681-689.
    • (2008) Brain , vol.131 , pp. 681-689
    • Klöppel, S.1    Stonnington, C.M.2    Chu, C.3    Draganski, B.4    Scahill, R.5
  • 32
    • 79955059574 scopus 로고    scopus 로고
    • Automatic classification of patients with Alzheimer's disease from structural MRI: A comparison of ten methods using the ADNI database
    • Cuingnet R, Gerardin E, Tessieras J, Auzias G, Lehéricy S, et al. (2011) Automatic classification of patients with Alzheimer's disease from structural MRI: A comparison of ten methods using the ADNI database. NeuroImage 56: 766-781.
    • (2011) NeuroImage , vol.56 , pp. 766-781
    • Cuingnet, R.1    Gerardin, E.2    Tessieras, J.3    Auzias, G.4    Lehéricy, S.5
  • 33
    • 80052169077 scopus 로고    scopus 로고
    • Effects of hardware heterogeneity on the performance of SVM Alzheimer's disease classifier
    • Abdulkadir A, Mortamet B, Vemuri P, Jack CR, Krueger G, et al. (2011) Effects of hardware heterogeneity on the performance of SVM Alzheimer's disease classifier. NeuroImage 58: 785-792.
    • (2011) NeuroImage , vol.58 , pp. 785-792
    • Abdulkadir, A.1    Mortamet, B.2    Vemuri, P.3    Jack, C.R.4    Krueger, G.5
  • 34
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman, D F, Price D, et al. (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34: 939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.F.2    Price, D.3
  • 35
    • 0024453856 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease
    • Morris JC, Heyman A, Mohs RC, Hughes JP, van Belle G, et al. (1989) The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology 39: 1159-1165.
    • (1989) Neurology , vol.39 , pp. 1159-1165
    • Morris, J.C.1    Heyman, A.2    Mohs, R.C.3    Hughes, J.P.4    van Belle, G.5
  • 37
    • 7044260964 scopus 로고    scopus 로고
    • Advances in functional and structural MR image analysis and implementation as FSL
    • Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TEJ, et al. (2004) Advances in functional and structural MR image analysis and implementation as FSL. NeuroImage 23Supplement 1: S208-S219.
    • (2004) NeuroImage , vol.23
    • Smith, S.M.1    Jenkinson, M.2    Woolrich, M.W.3    Beckmann, C.F.4    Behrens, T.E.J.5
  • 38
    • 0033179190 scopus 로고    scopus 로고
    • Detecting Structural Changes in Whole Brain Based on Nonlinear Deformations-Application to Schizophrenia Research
    • Gaser C, Volz H-P, Kiebel S, Riehemann S, Sauer H, (1999) Detecting Structural Changes in Whole Brain Based on Nonlinear Deformations-Application to Schizophrenia Research. NeuroImage 10: 107-113.
    • (1999) NeuroImage , vol.10 , pp. 107-113
    • Gaser, C.1    Volz, H.-P.2    Kiebel, S.3    Riehemann, S.4    Sauer, H.5
  • 40
    • 0242410408 scopus 로고    scopus 로고
    • Benchmarking Attribute Selection Techniques for Discrete Class Data Mining
    • Hall MA, Holmes G, (2003) Benchmarking Attribute Selection Techniques for Discrete Class Data Mining. IEEE Transactions On Knowledge And Data Engineering 15: 1437-1447.
    • (2003) IEEE Transactions On Knowledge And Data Engineering , vol.15 , pp. 1437-1447
    • Hall, M.A.1    Holmes, G.2
  • 43
    • 22044455069 scopus 로고    scopus 로고
    • Density-Based Clustering in Spatial Databases: The Algorithm GDBSCAN and Its Applications
    • Sander J, Ester M, Kriegel H-P, Xu X, (1998) Density-Based Clustering in Spatial Databases: The Algorithm GDBSCAN and Its Applications. Data Min Knowl Discov 2: 169-194.
    • (1998) Data Min Knowl Discov , vol.2 , pp. 169-194
    • Sander, J.1    Ester, M.2    Kriegel, H.-P.3    Xu, X.4
  • 44
    • 79952056311 scopus 로고    scopus 로고
    • Visualization of nonlinear kernel models in neuroimaging by sensitivity maps
    • Rasmussen PM, Madsen KH, Lund TE, Hansen LK, (2011) Visualization of nonlinear kernel models in neuroimaging by sensitivity maps. NeuroImage 55: 1120-1131.
    • (2011) NeuroImage , vol.55 , pp. 1120-1131
    • Rasmussen, P.M.1    Madsen, K.H.2    Lund, T.E.3    Hansen, L.K.4
  • 50
    • 0037213433 scopus 로고    scopus 로고
    • Efficient principal component analysis for multivariate 3D voxel-based mapping of brain functional imaging data sets as applied to FDG-PET and normal aging
    • Zuendorf G, Kerrouche N, Herholz K, Baron J-C, (2003) Efficient principal component analysis for multivariate 3D voxel-based mapping of brain functional imaging data sets as applied to FDG-PET and normal aging. Human Brain Mapping 18: 13-21.
    • (2003) Human Brain Mapping , vol.18 , pp. 13-21
    • Zuendorf, G.1    Kerrouche, N.2    Herholz, K.3    Baron, J.-C.4
  • 51
    • 84878555203 scopus 로고
    • Statistical power analysis for the behavioral sciences: Lawrence Erlbaum Associates
    • Cohen J (1988) Statistical power analysis for the behavioral sciences: Lawrence Erlbaum Associates.
    • (1988)
    • Cohen, J.1
  • 53
    • 33646072746 scopus 로고    scopus 로고
    • White matter damage of patients with Alzheimer's disease correlated with the decreased cognitive function
    • Duan J-H, Wang H-Q, Xu J, Lin X, Chen S-Q, et al. (2006) White matter damage of patients with Alzheimer's disease correlated with the decreased cognitive function. Surgical and Radiologic Anatomy 28: 150-156.
    • (2006) Surgical and Radiologic Anatomy , vol.28 , pp. 150-156
    • Duan, J.-H.1    Wang, H.-Q.2    Xu, J.3    Lin, X.4    Chen, S.-Q.5
  • 55
    • 0034064139 scopus 로고    scopus 로고
    • Corpus Callosum Measurement as an in Vivo Indicator for Neocortical Neuronal Integrity, but not White Matter Pathology, in Alzheimer's Disease
    • Hampel H, Teipel SJ, Alexander GE, Horwitz B, Pietrini P, et al. (2000) Corpus Callosum Measurement as an in Vivo Indicator for Neocortical Neuronal Integrity, but not White Matter Pathology, in Alzheimer's Disease. Annals of the New York Academy of Sciences 903: 470-476.
    • (2000) Annals of the New York Academy of Sciences , vol.903 , pp. 470-476
    • Hampel, H.1    Teipel, S.J.2    Alexander, G.E.3    Horwitz, B.4    Pietrini, P.5
  • 56
    • 84868304450 scopus 로고    scopus 로고
    • Correlation between cognitive function and the association fibers in patients with Alzheimer's disease using diffusion tensor imaging
    • Meng J-Z, Guo L-W, Cheng H, Chen Y-J, Fang L, et al. (2012) Correlation between cognitive function and the association fibers in patients with Alzheimer's disease using diffusion tensor imaging. Journal of Clinical Neuroscience 19: 1659-1663.
    • (2012) Journal of Clinical Neuroscience , vol.19 , pp. 1659-1663
    • Meng, J.-Z.1    Guo, L.-W.2    Cheng, H.3    Chen, Y.-J.4    Fang, L.5
  • 57
    • 0033798013 scopus 로고    scopus 로고
    • Loss of connectivity in Alzheimer's disease: an evaluation of white matter tract integrity with colour coded MR diffusion tensor imaging
    • Rose SE, Chen F, Chalk JB, Zelaya FO, Strugnell WE, et al. (2000) Loss of connectivity in Alzheimer's disease: an evaluation of white matter tract integrity with colour coded MR diffusion tensor imaging. J Neurol Neurosurg Psychiatry 69: 528-530.
    • (2000) J Neurol Neurosurg Psychiatry , vol.69 , pp. 528-530
    • Rose, S.E.1    Chen, F.2    Chalk, J.B.3    Zelaya, F.O.4    Strugnell, W.E.5
  • 58
    • 0037016165 scopus 로고    scopus 로고
    • Diffusion tensor in posterior cingulate gyrus: correlation with cognitive decline in Alzheimer's disease
    • Yoshiura T, Mihara F, Ogomori K, Tanaka A, Kaneko K, et al. (2002) Diffusion tensor in posterior cingulate gyrus: correlation with cognitive decline in Alzheimer's disease. NeuroReport 13: 2299-2302.
    • (2002) NeuroReport , vol.13 , pp. 2299-2302
    • Yoshiura, T.1    Mihara, F.2    Ogomori, K.3    Tanaka, A.4    Kaneko, K.5
  • 59
    • 77149157505 scopus 로고    scopus 로고
    • Microstructural Diffusion Changes are Independent of Macrostructural Volume Loss in Moderate to Severe Alzheimer's Disease
    • Canu E, McLaren DG, Fitzgerald ME, Bendlin BB, Zoccatelli G, et al. (2010) Microstructural Diffusion Changes are Independent of Macrostructural Volume Loss in Moderate to Severe Alzheimer's Disease. Journal of Alzheimer's Disease 19: 963-976.
    • (2010) Journal of Alzheimer's Disease , vol.19 , pp. 963-976
    • Canu, E.1    McLaren, D.G.2    Fitzgerald, M.E.3    Bendlin, B.B.4    Zoccatelli, G.5
  • 60
    • 61649126837 scopus 로고    scopus 로고
    • Diffusion abnormality in the posterior cingulum and hippocampal volume: correlation with disease progression in Alzheimer's disease
    • Nakata Y, Sato N, Nemoto K, Abe O, Shikakura S, et al. (2009) Diffusion abnormality in the posterior cingulum and hippocampal volume: correlation with disease progression in Alzheimer's disease. Magnetic Resonance Imaging 27: 347-354.
    • (2009) Magnetic Resonance Imaging , vol.27 , pp. 347-354
    • Nakata, Y.1    Sato, N.2    Nemoto, K.3    Abe, O.4    Shikakura, S.5
  • 61
    • 70349959901 scopus 로고    scopus 로고
    • Combining shape and connectivity analysis: An MRI study of thalamic degeneration in Alzheimer's disease
    • Zarei M, Patenaude B, Damoiseaux J, Morgese C, Smith S, et al. (2010) Combining shape and connectivity analysis: An MRI study of thalamic degeneration in Alzheimer's disease. NeuroImage 49: 1-8.
    • (2010) NeuroImage , vol.49 , pp. 1-8
    • Zarei, M.1    Patenaude, B.2    Damoiseaux, J.3    Morgese, C.4    Smith, S.5
  • 62
    • 84859410221 scopus 로고    scopus 로고
    • New MRI Markers for Alzheimer's Disease: A Meta-Analysis of Diffusion Tensor Imaging and a Comparison with Medial Temporal Lobe Measurements
    • Clerx L, Visser PJ, Verhey F, Aalten P, (2012) New MRI Markers for Alzheimer's Disease: A Meta-Analysis of Diffusion Tensor Imaging and a Comparison with Medial Temporal Lobe Measurements. Journal of Alzheimer's Disease 29: 405-429.
    • (2012) Journal of Alzheimer's Disease , vol.29 , pp. 405-429
    • Clerx, L.1    Visser, P.J.2    Verhey, F.3    Aalten, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.