Dietary lipids and sweeteners regulate glucagon-like peptide-2 secretion

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 304, Issue 8, 2013, Pages

  Sato, Shingo ^a   Hokari, Ryota ^a   Kurihara, Chie ^a   Sato, Hirokazu ^a   Narimatsu, Kazuyuki ^a   Hozumi, Hideaki ^a   Ueda, Toshihide ^a   Higashiyama, Masaaki ^a   Okada, Yoshikiyo ^a   Watanabe, Chikako ^a   Komoto, Shunsuke ^a   Tomita, Kengo ^a   Kawaguchi, Atsushi ^a   Nagao, Shigeaki ^a   Miura, Soichiro ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Fatty acids; Glucagon like peptide 2; Sweet taste receptor; Sweeteners

Indexed keywords

CARBOHYDRATE; FATTY ACID; GLUCAGON LIKE PEPTIDE 2; GLUCOSE; LACTISOLE; LINOLENIC ACID; SWEETENING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CARBOHYDRATE DIET; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FAT INTAKE; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; RAT; REGULATORY MECHANISM; TASTE BUD; THORACIC DUCT;

ANIMALS; BENZENE DERIVATIVES; CELL LINE, TUMOR; DIETARY CARBOHYDRATES; DIETARY FATS; ENTEROENDOCRINE CELLS; FATTY ACIDS, MONOUNSATURATED; FATTY ACIDS, UNSATURATED; GLUCAGON-LIKE PEPTIDE 2; GLUCOSE; HUMANS; LYMPHATIC SYSTEM; MALE; RATS; RATS, WISTAR; SWEETENING AGENTS; TASTE; THORACIC DUCT; VENULES;

EID: 84878578595     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00282.2012     Document Type: Article

References (37)

1. Beglinger S, Drewe J, Schirra J, Göke B, D'Amato M, Beglinger C. Role of fat hydrolysis in regulating glucagon-like Peptide-1 secretion. J Clin Endocrinol Metab 95: 879-886, 2010.
2. Belluzzi A, Brignola C, Campieri M, Pera A, Boschi S, Miglioli M. Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease. N Engl J Med 334: 1557-1560, 1996.
3. Bollman JL, Cain JC, Grindlay JH. Techniques for the collection of lymph from the liver, small intestine, or thoracic duct of the rat. J Lab Clin Med 33: 1349-1352, 1948.
4. Brown RJ, Walter M, Rother KI. Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion. Diabetes Care 32: 2184-2186, 2009.
5. Cani PD, Possemiers S, Van de Wiele T, Guiot Y, Everard A, Rottier O, Geurts L, Naslain D, Neyrinck A, Lambert DM, Muccioli GG, Delzenne NM. Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Gut 58: 1091-1103, 2009.
6. D'Alessio D, Lu W, Sun W, Zheng S, Yang Q, Seeley R, Woods SC, Tso P. Fasting and postprandial concentrations of GLP-1 intestinal lymph and portal plasma: evidence for selective release of GLP-1 in the lymph system. Am J Physiol Regul Integr Comp Physiol 293: R2163-R2169, 2007.
7. Dhanvantari S, Seidah NG, Brubaker PL. Role of prohormone convertases in the tissue-specific processing of proglucagon. Mol Endocrinol 10: 342-55, 1996.
8. DiBaise JK, Young RJ, Vanderhoof JA. Intestinal rehabilitation and the short bowel syndrome. Am J Gastroenterol 99: 1386-1395, 2004.
9. Drucker DJ, Erlich P, Asa SL, Brubaker PL. Induction of intestinal epithelial proliferation by glucagon-like peptide 2. Proc Natl Acad Sci USA 93: 7911-7916, 1996.
10. Drucker DJ. Minireview: the glucagon-like peptides. Endocrinology 142: 521-527, 2001.
11. Dube PE, Brubaker PL. Frontiers in glucagon-like peptide-2: multiple actions, multiple mediators. Am J Physiol Endocrinol Metab 293: E460-E465, 2007.
12. Edfalk S, Steneberg P, Edlund H. Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion. Diabetes 57: 2280-2287, 2008.
13. Feltrin KL, Patterson M, Ghatei MA, Bloom SR, Meyer JH, Horowitz M, Feinle-Bisset C. Effect of fatty acid chain length on suppression of ghrelin and stimulation of PYY, GLP-2 and PP secretion in healthy men. Peptides 27: 1638-1643, 2000.
14. Ford HE, Peters V, Martin NM, Ghatei MA, Frost GS, Bloom SR. Effects of oral ingestion of sucralose on gut hormone response and appetite in healthy normal-weight subjects. Eur J Clin Nutr 65: 508-513, 2011.
15. Fujita Y, Wideman RD, Speck M, Asadi A, King DS, Webber TD, Haneda M, Kieffer TJ. Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo. Am J Physiol Endocrinol Metab 296: E473-E479, 2009.
16. Hartmann B, Harr MB, Jeppesen PB, Wojdemann M, Deacon CF, Mortensen PB, Holst JJ. In vivo and in vitro degradation of glucagonlike peptide-2 in humans. J Clin Endocrinol Metab 85: 2884-2888, 2000.
17. Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, Yamada M, Sugimoto Y, Miyazaki S, Tsujimoto G. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med 11: 90-94, 2005.
18. Iakoubov R, Izzo A, Yeung A, Whiteside CI, Brubaker PL. Protein kinase Czeta is required for oleic acid-induced secretion of glucagon-like peptide-1 by intestinal endocrine L cells. Endocrinology 148: 1089-1098, 2007.
19. Itoh Y, Kawamata Y, Harada M, Koboyashi M, Fuihi R, Fukusumi S, Ogi K, Hosoya M, Tanaka Y, Uejima H, Tanaka H, Maruyama M, Satoh R, Okubo S, Kizawa H, Komatsu H, Matsumura F, Noguchi Y, Shinohara T, Himuna S, Fujisawa Y, Fujino M. Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature 422: 173-176, 2003.
20. Izumi H, Ishizuka S, Inafune A, Hira T, Ozawa K, Shimizu T, Takase M, Hara H. alpha-Lactalbumin hydrolysate stimulates glucagon-like peptide-2 secretion and small intestinal growth in suckling rats. J Nutr 139: 1322-1327, 2009.
21. Jang HJ, Kokrashvili Z, Theodorakis MJ, Carlson OD, Kim BJ, Zhou J, Kim HH, Xu X, Chan SL, Juhaszova M, Bernier M, Mosinger B. Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc Natl Acad Sci USA 104: 15069-15074, 2007.
22. Knight I. The development and applications of sucralose, a new highintensity sweetener. Can J Physiol Pharmacol 72: 435-439, 1994.
23. Kouris GJ, Liu Q, Rossi H, Djuricin G, Gattuso P, Nathan C, Weinstein RA, Prinz RA. The effect of glucagon-like peptide 2 on intestinal permeability and bacterial translocation in acute necrotizing pancreatitis. Am J Surg 181: 571-575, 2001.
24. Lauffer LM, Iakoubov R, Brubaker PL. GPR119 is essential for oleoylethanolamide-induced glucagon-like peptide-1 secretion from the intestinal enteroendocrine L-cell. Diabetes 58: 1058-66, 2009.
25. Lu WJ, Yang Q, Sun W, Woods SC, D'Alessio D, Tso P. The regulation of the lymphatic secretion of glucagon-like peptide-1 (GLP-1) by intestinal absorption of fat and carbohydrate. Am J Physiol Gastrointest Liver Physiol 293: G963-G971, 2007.
26. +-glucose cotransporter 1. Proc Natl Acad Sci USA 104: 15075-15080, 2007.
27. Miura S, Tsuzuki Y, Hokari R, Ishii H. Modulation of intestinal immune system by dietary fat intake: relevance to Crohn's disease. J Gastroenterol Hepatol 13: 1183-1190, 1998.
28. Orskov C, Holst JJ. Radio-immunoassays for glucagon-like peptides 1 and 2 (GLP-1 and GLP-2). Scand J Clin Lab Invest 47: 165-74, 1987.
29. Reimer RA, Darimont C, Gremlich S, Nicolas-Metral V, Ruegg UT, Mace K. A human cellular model for studying the regulation of glucagonlike peptide-1 secretion. Endocrinology 142: 4522-4528, 2001.
30. Rocca AS, Brubaker PL. Stereospecific effects of fatty acids on proglucagon-derived peptide secretion in fetal rat intestinal cultures. Endocrinology 136: 5593-5599, 1995.
31. Ruthig DJ, Meckling-Gill KA. Both (n-3) and (n-6) fatty acids stimulate wound healing in the rat intestinal epithelial cell line, IEC-6. J Nutr 129: 1791-1798, 1999.
32. Schiffman SS, Sattely-Miller EA, Graham BG, Bennett JL, Booth BJ, Desai N, Bishay I. Effect of temperature, pH, and ions on sweet taste. Physiol Behav 68: 469-481, 2000.
33. Talukdar S, Olefsky JM, Osborn O. Targeting GPR120 and other fatty acid-sensing GPCRs ameliorate insulin resistance and inflammatory diseases. Trends Pharmacol Sci 32: 543-550, 2011.
34. Tanaka T, Yano T, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G. Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells. Naunyn Schmiedebergs Arch Pharmacol 377: 515-522, 2008.
35. Tappenden A, Albin M, Bartholome AL, Mangian HF. Glucagon-like peptide-2 and acids: a short-chain fatty acids: a new twist to an old story. J Nutr 133: 3717-3720, 2003.
36. Wallis K, Walters JR, Gabe S. Short bowel syndrome: the role of GLP-2 on improving outcome. Curr Opin Clin Nutr Metab Care 12: 526-532, 2009.
37. Xiao Q, Boushey RP, Cino M, Drucker DJ, Brubaker PL. Circulating levels of glucagon-like peptide-2 in human subjects with inflammatory bowel disease. Am J Physiol Regul Integr Comp Physiol 278: R1057-R1063, 2000.