Effect of fatty acid chain length on suppression of ghrelin and stimulation of PYY, GLP-2 and PP secretion in healthy men

Peptides

Volumn 27, Issue 7, 2006, Pages 1638-1643

  Feltrin, Kate L ^a   Patterson, Michael ^b   Ghatei, Mohammad A ^b   Bloom, Stephen R ^b   Meyer, James H ^a   Horowitz, Michael ^a   Feinle Bisset, Christine ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Fatty acid chain length; Ghrelin; Glucagon like peptide 2; Pancreatic polypeptide; Peptide YY

Indexed keywords

DECANOIC ACID; FATTY ACID; GHRELIN; GLUCAGON LIKE PEPTIDE 2; LAURIC ACID; PANCREAS POLYPEPTIDE; PEPTIDE YY;

ADULT; ARTICLE; CONTROLLED STUDY; HORMONE BLOOD LEVEL; HORMONE RELEASE; HUMAN; MALE; MEAL; NORMAL HUMAN; PRIORITY JOURNAL;

ADULT; ANIMALS; DUODENUM; FATTY ACIDS; FEEDING BEHAVIOR; GLUCAGON-LIKE PEPTIDE 2; GLUCAGON-LIKE PEPTIDES; HUMANS; MALE; MIDDLE AGED; PANCREATIC POLYPEPTIDE; PEPTIDE HORMONES; PEPTIDE YY; RATS; TIME FACTORS;

EID: 33745007565     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2006.01.023     Document Type: Article

References (40)

1. Adrian T.E., Bloom S.R., Bryant M.G., Polak J.M., Heitz P.H., and Barnes A.J. Distribution and release of human pancreatic polypeptide. Gut 17 (1976) 940-944
2. Adrian T.E., Ferri G.L., Bacarese-Hamilton A.J., Fuessl H.S., Polak J.M., and Bloom S.R. Human distribution and release of a putative new gut hormone, peptide YY. Gastroenterology 89 (1985) 1070-1077
3. Batterham R.L., Cohen M.A., Ellis S.M., Le Roux C.W., Withers D.J., Frost G.S., et al. Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med 349 (2003) 941-948
4. Batterham R.L., Cowley M.A., Small C.J., Herzog H., Cohen M.A., Dakin C.L., et al. Gut hormone PYY(3-36) physiologically inhibits food intake. Nature 418 (2002) 650-654
5. Batterham R.L., Le Roux C.W., Cohen M.A., Park A.J., Ellis S.M., Patterson M., et al. Pancreatic polypeptide reduces appetite and food intake in humans. J Clin Endocrinol Metab 88 (2003) 3989-3992
6. Chapman I.M., Goble E.A., Wittert G.A., and Horowitz M. Effects of small-intestinal fat and carbohydrate infusions on appetite and food intake in obese and nonobese men. Am J Clin Nutr 69 (1999) 6-12
7. Cummings D.E., Purnell J.Q., Frayo R.S., Schmidova K., Wisse B.E., and Weigle D.S. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 50 (2001) 1714-1719
8. Eissele R., Goke R., Willemer S., Harthus H.P., Vermeer H., Arnold R., et al. Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. Eur J Clin Invest 22 (1992) 283-291
9. Erdmann J., Lippl F., and Schusdziarra V. Differential effect of protein and fat on plasma ghrelin levels in man. Regul Pept 116 (2003) 101-107
10. Erdmann J., Lippl F., Wagenpfeil S., and Schusdziarra V. Differential association of basal and postprandial plasma ghrelin with leptin, insulin, and type 2 diabetes. Diabetes 54 (2005) 1371-1378
11. Feinle C., O'Donovan D.G., Doran S., Andrews J.M., Wishart J., Chapman I., et al. Effects of fat digestion on appetite, APD motility, and gut hormones in response to duodenal fat infusion in humans. Am J Physiol Gastrointest Liver Physiol 284 (2003) G798-G807
12. Feinle-Bisset C., Patterson M., Ghatei M.A., Bloom S.R., and Horowitz M. Fat digestion is required for the suppression of ghrelin and stimulation of peptide YY and pancreatic polypeptide secretion by intraduodenal lipid. Am J Physiol Endocrinol Metab 289 (2005) E948-E953
13. Feltrin K.L., Little T.J., Meyer J.H., Horowitz M., Smout A.J., Wishart J., et al. Effects of intraduodenal fatty acids on appetite, antropyloroduodenal motility, and plasma CCK and GLP-1 in humans vary with their chain length. Am J Physiol Regul Integr Comp Physiol 287 (2004) R524-R533
14. Flint A., Raben A., Astrup A., and Holst J.J. Glucagon-like peptide-1 promotes satiety and suppresses energy intake in humans. J Clin Invest 101 (1998) 515-520
15. Greenman Y., Golani N., Gilad S., Yaron M., Limor R., and Stern N. Ghrelin secretion is modulated in a nutrient- and gender-specific manner. Clin Endocrinol (Oxf) 60 (2004) 382-388
16. Heddle R., Collins P.J., Dent J., Horowitz M., Read N.W., Chatterton B., et al. Motor mechanisms associated with slowing of the gastric emptying of a solid meal by an intraduodenal lipid infusion. J Gastroenterol Hepatol 4 (1989) 437-447
17. Kissileff H.R., Pi-Sunyer F.X., Thornton J., and Smith G.P. C-terminal octapeptide of cholecystokinin decreases food intake in man. Am J Clin Nutr 34 (1981) 154-160
18. Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402 (1999) 656-660
19. Koop I., Ruppert-Seipp G., Koop H., Schafmayer A., and Arnold R. Cholecystokinin release by gastric distension-an atropine-sensitive mechanism. Digestion 46 (1990) 220-227
20. Lavin J.H., Wittert G.A., Andrews J.M., Yeap B., Wishart J.M., Morris H.A., et al. Interaction of insulin, glucagon-like peptide 1, gastric inhibitory polypeptide, and appetite in response to intraduodenal carbohydrate. Am J Clin Nutr 68 (1998) 591-598
21. Lilja P., Wiener I., Inoue K., Fried G.M., Greeley G.H.J., and Thompson J.C. Release of cholecystokinin in response to food and intraduodenal fat in pigs, dogs and man. Surg Gynecol Obstet 159 (1984) 557-561
22. Lin H.C., and Chey W.Y. Cholecystokinin and peptide YY are released by fat in either proximal or distal small intestine in dogs. Regul Pept 114 (2003) 131-135
23. Lin H.C., Chey W.Y., and Zhao X. Release of distal gut peptide YY (PYY) by fat in proximal gut depends on CCK. Peptides 21 (2000) 1561-1563
24. Lippl F., Kircher F., Erdmann J., Allescher H.D., and Schusdziarra V. Effect of GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach. Regul Pept 119 (2004) 93-98
25. Little T.J., Feltrin K.L., Horowitz M., Smout A.J., Rades T., Meyer J.H., et al. Dose-related effects of lauric acid on antropyloroduodenal motility, gastrointestinal hormone release, appetite, and energy intake in healthy men. Am J Physiol Regul Integr Comp Physiol 289 (2005) R1090-R1098
26. McDonald G.B., and Weidman M. Partitioning of polar fatty acids into lymph and portal vein after intestinal absorption in the rat. Q J Exp Physiol 72 (1987) 153-159
27. 2+-dependent mechanism in the enteroendocrine cell line STC-1. J Physiol (Lond) 513 (1998) 11-18
28. Mentlein R., Dahms P., Grandt D., and Kruger R. Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV. Regul Pept 49 (1993) 133-144
29. Miazza B., Palma R., Lachance J.R., Chayvialle J.A., Jonard P.P., and Modigliani R. Jejunal secretory effect of intraduodenal food in humans. A comparison of mixed nutrients, proteins, lipids, and carbohydrates. Gastroenterology 88 (1985) 1215-1222
30. Mohlig M., Spranger J., Otto B., Ristow M., Tschop M., and Pfeiffer A.F. Euglycemic hyperinsulinemia, but not lipid infusion, decreases circulating ghrelin levels in humans. J Endocrinol Invest 25 (2002) RC36-RC38
31. Munroe D.G., Gupta A.K., Kooshesh F., Vyas T.B., Rizkalla G., Wang H., et al. Prototypic G protein-coupled receptor for the intestinotrophic factor glucagon-like peptide 2. Proc Natl Acad Sci USA 96 (1999) 1569-1573
32. Orskov C., Holst J.J., Knuhtsen S., Baldissera F.G., Poulsen S.S., and Nielsen O.V. Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas. Endocrinology 119 (1986) 1467-1475
33. Parker B.A., Doran S., Wishart J., Horowitz M., and Chapman I.M. Effects of small intestinal and gastric glucose administration on the suppression of plasma ghrelin concentrations in healthy older men and women. Clin Endocrinol (Oxf) 62 (2005) 539-546
34. Patterson M., Murphy K.G., le Roux C.W., Ghatei M.A., and Bloom S.R. Characterisation of ghrelin-like immunoreactivity in human plasma. J Clin Endocrinol Metab 90 (2005) 2205-2211
35. Schwartz T.W., Holst J.J., Fahrenkrug J., Jensen S.L., Nielsen O.V., Rehfeld J.F., et al. Cholinergic regulation of pancreatic polypeptide secretion. J Clin Invest 61 (1978) 781-789
36. Scott R.B., Kirk D., MacNaughton W.K., and Meddings J.B. GLP-2 augments the adaptive response to massive intestinal resection in rat. Am J Physiol Gastrointest Liver Physiol 275 (1998) G911-G921
37. Sorensen L.B., Flint A., Raben A., Hartmann B., Holst J.J., and Astrup A. No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects. Int J Obes Relat Metab Disord 27 (2003) 450-456
38. Tang-Christensen M., Larsen P.J., Thulesen J., Romer J., and Vrang N. The proglucagon-derived peptide, glucagon-like peptide-2, is a neurotransmitter involved in the regulation of food intake. Nat Med 6 (2000) 802-807
39. Wren A.M., Seal L.J., Cohen M.A., Brynes A.E., Frost G.S., Murphy K.G., et al. Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab 86 (2001) 5992-5995
40. Yusta B., Huang L., Munroe D., Wolff G., Fantaske R., Sharma S., et al. Enteroendocrine localization of GLP-2 receptor expression in humans and rodents. Gastroenterology 119 (2000) 744-755