Artemin-GFRα3 interactions partially contribute to acute inflammatory hypersensitivity

Neuroscience Letters

Volumn 545, Issue , 2013, Pages 23-28

  Thornton, Peter ^a   Hatcher, Jon P ^a   Robinson, Ian ^a   Sargent, Becky ^a   Franzén, Bo ^b   Martino, Giovanni ^c   Kitching, Lisa ^a   Glover, Colin P ^a   Anderson, Dina ^a   Forsmo Bruce, Heidi ^b   Low, Choon Pei ^a   Cusdin, Fiona ^a   Dosanjh, Bhupinder ^a   Williams, Wendy ^a   Steffen, Ann Charlott ^b   Thompson, Simon ^a   Eklund, Malin ^b   Lloyd, Chris ^a   Chessell, Iain ^a   Hughes, Jane ^a  

^a MEDIMMUNE   (United States)

^b ASTRAZENECA R AND D   (Sweden)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Artemin; DRG; Growth factors; Pain

Indexed keywords

ARTEMIN; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; GDNF FAMILY RECEPTOR ALPHA 3; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 002; MONOCLONAL ANTIBODY 006; MONOCLONAL ANTIBODY 1085; MONOCLONAL ANTIBODY 10851; MONOCLONAL ANTIBODY 2589; NEUTRALIZING ANTIBODY; PROTEIN RET; UNCLASSIFIED DRUG;

ACUTE INFLAMMATORY HYPERSENSITIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY AFFINITY; ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; HYPERSENSITIVITY; IC 50; INFLAMMATORY PAIN; MALE; MOUSE; NERVE LIGATION; NEUROBLASTOMA CELL; NOCICEPTION; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; SCIATIC NERVE; SPINAL GANGLION;

ANIMALS; GANGLIA, SPINAL; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; HOT TEMPERATURE; HYPERALGESIA; MALE; NERVE TISSUE PROTEINS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84878578528     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.04.007     Document Type: Article

References (21)

1. Baloh R.H., Tansey M.G., Lampe P.A., Fahrner T.J., Enomoto H., Simburger K.S., Leitner M.L., Araki T., Johnson E.M., Milbrandt J. Artemin a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. Neuron 1998, 21:1291-1302.
2. Bennett D.L., Boucher T.J., Michael G.J., Popat R.J., Malcangio M., Averill S.A., Poulsen K.T., Priestley J.V., Shelton D.L., McMahon S.B. Artemin has potent neurotrophic actions on injured C-fibres. J. Peripher. Nerv. Syst. 2006, 11:330-345.
3. Bespalov M.M., Sidorova Y.A., Tumova S., Ahonen-Bishopp A., Magalhaes A.C., Kulesskiy E., Paveliev M., Rivera C., Rauvala H., Saarma M. Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin. J. Cell Biol. 2011, 192:153-169.
4. Ceyhan G.O., Schafer K.H., Kerscher A.G., Rauch U., Demir I.E., Kadihasanoglu M., Bohm C., Muller M.W., Buchler M.W., Giese N.A., Erkan M., Friess H. Nerve growth factor and artemin are paracrine mediators of pancreatic neuropathy in pancreatic adenocarcinoma. Ann. Surg. 2010, 251:923-931.
5. Demir I.E., Friess H., Ceyhan G.O. Nerve-cancer interactions in the stromal biology of pancreatic cancer. Front. Physiol. 2012, 3:97.
6. Elitt C.M., McIlwrath S.L., Lawson J.J., Malin S.A., Molliver D.C., Cornuet P.K., Koerber H.R., Davis B.M., Albers K.M. Artemin overexpression in skin enhances expression of TRPV1 and TRPA1 in cutaneous sensory neurons and leads to behavioral sensitivity to heat and cold. J. Neurosci. 2006, 26:8578-8587.
7. Gardell L.R., Wang R., Ehrenfels C., Ossipov M.H., Rossomando A.J., Miller S., Buckley C., Cai A.K., Tse A., Foley S.F., Gong B., Walus L., Carmillo P., Worley D., Huang C., Engber T., Pepinsky B., Cate R.L., Vanderah T.W., Lai J., Sah D.W., Porreca F. Multiple actions of systemic artemin in experimental neuropathy. Nat. Med. 2003, 9:1383-1389.
8. Jankowski M.P., Rau K.K., Soneji D.J., Anderson C.E., Koerber H.R. Enhanced artemin/GFRalpha3 levels regulate mechanically insensitive, heat-sensitive C-fiber recruitment after axotomy and regeneration. J. Neurosci. 2010, 30:16272-16283.
9. Li S., Li Z., Guo F., Qin X., Liu B., Lei Z., Song Z., Sun L., Zhang H.T., You J., Zhou Q. miR-223 regulates migration and invasion by targeting artemin in human esophageal carcinoma. J. Biomed. Sci. 2011, 18:24.
10. Malin S.A., Davis B.M., Molliver D.C. Production of dissociated sensory neuron cultures and considerations for their use in studying neuronal function and plasticity. Nat. Protoc. 2007, 2:152-160.
11. Malin S.A., Molliver D.C., Koerber H.R., Cornuet P., Frye R., Albers K.M., Davis B.M. Glial cell line-derived neurotrophic factor family members sensitize nociceptors in vitro and produce thermal hyperalgesia in vivo. J. Neurosci. 2006, 26:8588-8599.
12. Murota H., Izumi M., Abd El-Latif M.I., Nishioka M., Terao M., Tani M., Matsui S., Sano S., Katayama I. Artemin causes hypersensitivity to warm sensation, mimicking warmth-provoked pruritus in atopic dermatitis. J. Allergy Clin. Immunol. 2012, 130:671-682. e674.
13. Newton P., Harrison P., Clulow S. A novel method for determination of the affinity of protein: protein interactions in homogeneous assays. J. Biomol. Screen. 2008, 13:674-682.
14. Paveliev M., Airaksinen M.S., Saarma M. GDNF family ligands activate multiple events during axonal growth in mature sensory neurons. Mol. Cell. Neurosci. 2004, 25:453-459.
15. Paveliev M., Hienola A., Jokitalo E., Planken A., Bespalov M.M., Rauvala H., Saarma M. Sensory neurons from N-syndecan-deficient mice are defective in survival. Neuroreport 2008, 19:1397-1400.
16. Randall L.O., Selitto J.J. A method for measurement of analgesic activity on inflamed tissue. Arch. Int. Pharmacodyn. Ther. 1957, 111:409-419.
17. Schmutzler B.S., Roy S., Hingtgen C.M. Glial cell line-derived neurotrophic factor family ligands enhance capsaicin-stimulated release of calcitonin gene-related peptide from sensory neurons. Neuroscience 2009, 161:148-156.
18. Schueler-Furman O., Glick E., Segovia J., Linial M. Is GAS1 a co-receptor for the GDNF family of ligands?. Trends Pharmacol. Sci. 2006, 27:72-77.
19. Tanaka T., Shinoda M., Feng B., Albers K.M., Gebhart G.F. Modulation of visceral hypersensitivity by glial cell line-derived neurotrophic factor family receptor α-3 in colorectal afferents. Am. J. Physiol. 2010, 300:G418-G424.
20. Wang X., Baloh R.H., Milbrandt J., Garcia K.C. Structure of artemin complexed with its receptor GFRalpha3: convergent recognition of glial cell line-derived neurotrophic factors. Structure 2006, 14:1083-1092.
21. Weinkauf B., Rukwied R., Quiding H., Dahllund L., Johansson P., Schmelz M. Local gene expression changes after UV-irradiation of human skin. PLoS ONE 2012, 7:e39411.